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Jia Wei, PhD

TitleDirector
Faculty RankProfessor
InstitutionUniversity of Hawaii at Manoa
DepartmentCancer Biology
AddressUniversity of Hawaii Cancer Center
701 Ilalo St
Honolulu HI 96813
Phone8085645823
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    Collapse Research 
    Collapse research activities and funding
    R01AA020212     (ZHOU, ZHANXIANG)Sep 30, 2010 - Feb 29, 2028
    NIH
    Aldehydes in Alcohol-Induced Organ Injury
    Role: Co-Principal Investigator
    U01CA188387     (JIA, WEI)Aug 1, 2015 - Jul 31, 2020
    NIH
    Gut microbiota mediated bile acid alterations in hepatic carcinogenesis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dai W, Xu Y, Mo S, Li Q, Yu J, Wang R, Ma Y, Ni Y, Xiang W, Han L, Zhang L, Cai S, Qin J, Chen WL, Jia W, Cai G. GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies. Signal Transduct Target Ther. 2020 09 02; 5(1):177. PMID: 32873793.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    2. Wang J, Wei R, Xie G, Arnold M, Kueider-Paisley A, Louie G, Mahmoudian Dehkordi S, Blach C, Baillie R, Han X, De Jager PL, Bennett DA, Kaddurah-Daouk R, Jia W. Peripheral serum metabolomic profiles inform central cognitive impairment. Sci Rep. 2020 08 20; 10(1):14059. PMID: 32820198.
      Citations: 23     Fields:    Translation:Humans
    3. Zhao A, Wang S, Chen W, Zheng X, Huang F, Han X, Ge K, Rajani C, Huang Y, Yu H, Zhu J, Jia W. Increased levels of conjugated bile acids are associated with human bile reflux gastritis. Sci Rep. 2020 07 14; 10(1):11601. PMID: 32665615.
      Citations: 14     Fields:    Translation:HumansAnimals
    4. Xie G, Wang X, Wei R, Wang J, Zhao A, Chen T, Wang Y, Zhang H, Xiao Z, Liu X, Deng Y, Wong L, Rajani C, Kwee S, Bian H, Gao X, Liu P, Jia W. Serum metabolite profiles are associated with the presence of advanced liver fibrosis in Chinese patients with chronic hepatitis B viral infection. BMC Med. 2020 06 05; 18(1):144. PMID: 32498677.
      Citations: 20     Fields:    Translation:Humans
    5. Wei M, Huang F, Zhao L, Zhang Y, Yang W, Wang S, Li M, Han X, Ge K, Qu C, Rajani C, Xie G, Zheng X, Zhao A, Bian Z, Jia W. A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility. EBioMedicine. 2020 May; 55:102766. PMID: 32408110.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    6. Huang F, Zheng X, Ma X, Jiang R, Zhou W, Zhou S, Zhang Y, Lei S, Wang S, Kuang J, Han X, Wei M, You Y, Li M, Li Y, Liang D, Liu J, Chen T, Yan C, Wei R, Rajani C, Shen C, Xie G, Bian Z, Li H, Zhao A, Jia W. Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism. Nat Commun. 2019 10 31; 10(1):4971. PMID: 31672964.
      Citations: 257     Fields:    Translation:HumansAnimalsCells
    7. Evangelista EB, Kwee SA, Sato MM, Wang L, Rettenmeier C, Xie G, Jia W, Wong LL. Phospholipids are A Potentially Important Source of Tissue Biomarkers for Hepatocellular Carcinoma: Results of a Pilot Study Involving Targeted Metabolomics. Diagnostics (Basel). 2019 Oct 29; 9(4). PMID: 31671805.
      Citations:    
    8. Li Y, Zheng X, Liang D, Zhao A, Jia W, Chen T. MCEE 2.0: more options and enhanced performance. Anal Bioanal Chem. 2019 Aug; 411(20):5089-5098. PMID: 31278548.
      Citations: 2     Fields:    Translation:Humans
    9. Zhang J, Gao LZ, Chen YJ, Zhu PP, Yin SS, Su MM, Ni Y, Miao J, Wu WL, Chen H, Brouwer KLR, Liu CX, Xu L, Jia W, Lan K. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species. Drug Metab Dispos. 2019 03; 47(3):283-294. PMID: 30606729.
      Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
    10. Fang C, Du H, Jia W, Xu Y. Compositional Differences and Similarities between Typical Chinese Baijiu and Western Liquor as Revealed by Mass Spectrometry-Based Metabolomics. Metabolites. 2018 Dec 21; 9(1). PMID: 30577624.
      Citations:    
    11. Zheng X, Wang S, Jia W. Calorie restriction and its impact on gut microbial composition and global metabolism. Front Med. 2018 Dec; 12(6):634-644. PMID: 30446879.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    12. Xie G, Wang X, Jiang R, Zhao A, Yan J, Zheng X, Huang F, Liu X, Panee J, Rajani C, Yao C, Yu H, Jia W, Sun B, Liu P, Jia W. Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure. EBioMedicine. 2018 Nov; 37:294-306. PMID: 30344125.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    13. Rajani C, Jia W. Bile acids and their effects on diabetes. Front Med. 2018 Dec; 12(6):608-623. PMID: 30306382.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    14. Wei R, Wang J, Wang X, Xie G, Wang Y, Zhang H, Peng CY, Rajani C, Kwee S, Liu P, Jia W. Clinical prediction of HBV and HCV related hepatic fibrosis using machine learning. EBioMedicine. 2018 Sep; 35:124-132. PMID: 30100397.
      Citations: 26     Fields:    Translation:HumansCells
    15. Zhu P, Zhang J, Chen Y, Yin S, Su M, Xie G, Brouwer KLR, Liu C, Lan K, Jia W. Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids. Anal Bioanal Chem. 2018 Aug; 410(21):5287-5300. PMID: 29907951.
      Citations: 14     Fields:    Translation:HumansCells
    16. Rajani C, Jia W. Disruptions in gut microbial-host co-metabolism and the development of metabolic disorders. Clin Sci (Lond). 2018 04 16; 132(7):791-811. PMID: 29661926.
      Citations: 16     Fields:    Translation:Humans
    17. Jia W, Rajani C. The Influence of Gut Microbial Metabolism on the Development and Progression of Non-alcoholic Fatty Liver Disease. Adv Exp Med Biol. 2018; 1061:95-110. PMID: 29956209.
      Citations: 15     Fields:    Translation:HumansAnimals
    18. Zheng X, Huang F, Zhao A, Lei S, Zhang Y, Xie G, Chen T, Qu C, Rajani C, Dong B, Li D, Jia W. Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice. BMC Biol. 2017 Dec 14; 15(1):120. PMID: 29241453.
      Citations: 135     Fields:    Translation:AnimalsCells
    19. Li B, He X, Jia W, Li H. Novel Applications of Metabolomics in Personalized Medicine: A Mini-Review. Molecules. 2017 Jul 13; 22(7). PMID: 28703775.
      Citations: 45     Fields:    Translation:Humans
    20. Yin S, Su M, Xie G, Li X, Wei R, Liu C, Lan K, Jia W. Factors affecting separation and detection of bile acids by liquid chromatography coupled with mass spectrometry in negative mode. Anal Bioanal Chem. 2017 Sep; 409(23):5533-5545. PMID: 28689325.
      Citations: 12     Fields:    Translation:HumansAnimals
    21. Yan J, Xie G, Liang C, Hu Y, Zhao A, Huang F, Hu P, Liu P, Jia W, Wang X. Herbal medicine Yinchenhaotang protects against a-naphthylisothiocyanate-induced cholestasis in rats. Sci Rep. 2017 06 23; 7(1):4211. PMID: 28646179.
      Citations: 24     Fields:    Translation:Animals
    22. Lei S, Huang F, Zhao A, Chen T, Chen W, Xie G, Zheng X, Zhang Y, Yu H, Zhang P, Rajani C, Bao Y, Jia W, Jia W. The ratio of dihomo-?-linolenic acid to deoxycholic acid species is a potential biomarker for the metabolic abnormalities in obesity. FASEB J. 2017 09; 31(9):3904-3912. PMID: 28490483.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    23. Zhao L, Ni Y, Yu H, Zhang P, Zhao A, Bao Y, Liu J, Chen T, Xie G, Panee J, Chen W, Rajani C, Wei R, Su M, Jia W, Jia W. Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity. FASEB J. 2017 04; 31(4):1449-1460. PMID: 28007782.
      Citations: 21     Fields:    Translation:Humans
    24. Qian L, Zhao A, Zhang Y, Chen T, Zeisel SH, Jia W, Cai W. Metabolomic Approaches to Explore Chemical Diversity of Human Breast-Milk, Formula Milk and Bovine Milk. Int J Mol Sci. 2016 Dec 17; 17(12). PMID: 27999311.
      Citations: 17     Fields:    Translation:Humans
    25. Chen WL, Wang YY, Zhao A, Xia L, Xie G, Su M, Zhao L, Liu J, Qu C, Wei R, Rajani C, Ni Y, Cheng Z, Chen Z, Chen SJ, Jia W. Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential. Cancer Cell. 2016 Nov 14; 30(5):779-791. PMID: 27746145.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    26. Fu Y, Biglia N, Wang Z, Shen Y, Risch HA, Lu L, Canuto EM, Jia W, Katsaros D, Yu H. Long non-coding RNAs, ASAP1-IT1, FAM215A, and LINC00472, in epithelial ovarian cancer. Gynecol Oncol. 2016 Dec; 143(3):642-649. PMID: 27667152.
      Citations: 38     Fields:    Translation:Humans
    27. Zhou K, Xie G, Wen J, Wang J, Pan W, Zhou Y, Xiao Y, Wang Y, Jia W, Cai W. Histamine is correlated with liver fibrosis in biliary atresia. Dig Liver Dis. 2016 Aug; 48(8):921-6. PMID: 27257052.
      Citations: 11     Fields:    Translation:Humans
    28. Huang S, Chong N, Lewis NE, Jia W, Xie G, Garmire LX. Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis. Genome Med. 2016 Mar 31; 8(1):34. PMID: 27036109.
      Citations: 86     Fields:    Translation:Humans
    29. He X, Ji G, Jia W, Li H. Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanism and Application of Metabolomics. Int J Mol Sci. 2016 Mar 15; 17(3):300. PMID: 26999104.
      Citations: 38     Fields:    Translation:Humans
    30. Ferslew BC, Xie G, Johnston CK, Su M, Stewart PW, Jia W, Brouwer KL, Barritt AS. Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis. Dig Dis Sci. 2015 Nov; 60(11):3318-28. PMID: 26138654.
      Citations: 173     Fields:    Translation:Humans
    31. Zheng X, Xie G, Jia W. Metabolomic profiling in colorectal cancer: opportunities for personalized medicine. Per Med. 2013 Sep; 10(7):741-755. PMID: 29768755.
      Citations: 5     Fields:    
    32. Qiu Y, Zhou B, Su M, Baxter S, Zheng X, Zhao X, Yen Y, Jia W. Mass spectrometry-based quantitative metabolomics revealed a distinct lipid profile in breast cancer patients. Int J Mol Sci. 2013 Apr 12; 14(4):8047-61. PMID: 23584023.
      Citations: 69     Fields:    Translation:Humans
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