Bile Acids and Salts

"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.

Descriptor ID	D001647
MeSH Number(s)	D04.210.500.105
Concept/Terms	Bile Acids and Salts Bile Acids and Salts Bile Acids Bile Acids Acids, Bile Bile Salts Bile Salts Salts, Bile

Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Bile Acids and Salts [D04.210.500.105]

Below are MeSH descriptors whose meaning is related to "Bile Acids and Salts".

Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".

Bile Acids and Salts
Cholic Acids

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.

Bar chart showing 30 publications over 17 distinct years, with a maximum of 5 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2001	1	0	1
2006	0	1	1
2008	0	1	1
2009	0	1	1
2013	0	1	1
2014	0	1	1
2015	3	1	4
2016	0	2	2
2017	2	2	4
2018	5	0	5
2019	1	0	1
2020	1	0	1
2021	0	1	1
2022	0	1	1
2023	1	2	3
2025	1	0	1

Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.

Kiaei N, Malik A, Idahosa SO, Lee KK, Endo-Umeda K, Makishima M, Kawamura A, Higuchi S. Python-derived 16a-Hydroxylated Bile Acid, Pythocholic Acid is a ligand for TGR5, not farnesoid X receptors and vitamin D receptors. Biochem Biophys Res Commun. 2025 03 05; 751:151453.

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Higuchi S, Wood C, Nasiri RH, Giddla LJ, Molina V, Diarra R, DiPatrizio NV, Kawamura A, Haeusler RA. The 16a-hydroxylated Bile Acid, Pythocholic Acid Decreases Food Intake and Increases Oleoylethanolamide in Male Mice. Endocrinology. 2023 08 01; 164(9).

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Lynch JB, Gonzalez EL, Choy K, Faull KF, Jewell T, Arellano A, Liang J, Yu KB, Paramo J, Hsiao EY. Gut microbiota Turicibacter strains differentially modify bile acids and host lipids. Nat Commun. 2023 06 20; 14(1):3669.

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Sisk-Hackworth L, Kelley ST, Thackray VG. Sex, puberty, and the gut microbiome. Reproduction. 2023 02 01; 165(2):R61-R74.

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Chowdhury AS, Geetha Bai R, Islam T, Abir M, Narayan M, Khatun Z, Nurunnabi M. Bile acid linked ?-glucan nanoparticles for liver specific oral delivery of biologics. Biomater Sci. 2022 May 31; 10(11):2929-2939.

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Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Sci Rep. 2021 02 16; 11(1):3881.

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Zhao A, Wang S, Chen W, Zheng X, Huang F, Han X, Ge K, Rajani C, Huang Y, Yu H, Zhu J, Jia W. Increased levels of conjugated bile acids are associated with human bile reflux gastritis. Sci Rep. 2020 07 14; 10(1):11601.

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Huang F, Zheng X, Ma X, Jiang R, Zhou W, Zhou S, Zhang Y, Lei S, Wang S, Kuang J, Han X, Wei M, You Y, Li M, Li Y, Liang D, Liu J, Chen T, Yan C, Wei R, Rajani C, Shen C, Xie G, Bian Z, Li H, Zhao A, Jia W. Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism. Nat Commun. 2019 10 31; 10(1):4971.

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Xie G, Wang X, Jiang R, Zhao A, Yan J, Zheng X, Huang F, Liu X, Panee J, Rajani C, Yao C, Yu H, Jia W, Sun B, Liu P, Jia W. Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure. EBioMedicine. 2018 Nov; 37:294-306.

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Rajani C, Jia W. Bile acids and their effects on diabetes. Front Med. 2018 Dec; 12(6):608-623.

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