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Kazuma Nakagawa, MD

TitleNeurointensivist
Faculty RankAssistant Professor
InstitutionUniversity of Hawaii
DepartmentMedicine
AddressThe Queen's Medical Center
1301 Punchbowl Street
Honolulu HI 96813
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    Other Positions
    TitleNeurointensivist
    InstitutionThe Queen''s Medical Center
    DepartmentNeuroscience Institute


    Collapse Biography 
    Collapse awards and honors
    2004Alpha Omega Alpha, University of Florida
    2008Young Investigator Award, Neurocritical Care Society
    2009Founders Award, American Academy of Neurology
    2012 - 2014Loan Repayment Program, NIH/NIMHD

    Collapse Overview 
    Collapse overview
    My clinical experience is caring for patients who are critically ill as a result of cerebrovascular diseases, including ischemic and hemorrhagic stroke. After starting a new academic career as a clinician investigator at the University of Hawaii and The Queen’s Medical Center, I have identified a new area of research interest: investigating racial disparities in risk factors and outcomes among stroke patients. By directly experiencing health disparities while practicing in Hawaii, I am now motivated to reduce the burden of ischemic and hemorrhagic strokes in Hawaii where many minority patients may be underserved. I am currently conducting a longitudinal cohort study of intracerebral hemorrhage patients who are hospitalized at the Queen’s Medical Center, to assess the disparities in risk factors and long-term outcomes among the Native Hawaiians and other Pacific Islanders. My long-term goal is to conduct a culturally sensitive, community-based intervention study that can improve stroke-related outcomes and reduce health disparities among Native Hawaiians/Pacific Islanders and other underserved minorities living in Hawaii.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bruno MK, Matsunaga M, Krening E, Nakagawa K, Chen JJ, Seto T, Gao F, Tanner C, Ross GW. Racial disparities in hospitalization characteristics among Native Hawaiians, Pacific Islanders and Asian American subgroups with Parkinson's disease. Parkinsonism Relat Disord. 2024 Apr; 121:106018. PMID: 38359475.
      Citations: 1     Fields:    Translation:Humans
    2. Chen R, Morris BJ, Donlon TA, Ross GW, Kallianpur KJ, Allsopp RC, Nakagawa K, Willcox BJ, Masaki KH. Incidence of Alzheimer's Disease in Men with Late-Life Hypertension Is Ameliorated by FOXO3 Longevity Genotype. J Alzheimers Dis. 2023; 95(1):79-91. PMID: 37483002.
      Citations: 2     Fields:    Translation:Humans
    3. Donlon TA, Morris BJ, Masaki KH, Chen R, Davy PMC, Kallianpur KJ, Nakagawa K, Owens JB, Willcox DC, Allsopp RC, Willcox BJ. FOXO3, a Resilience Gene: Impact on Lifespan, Healthspan, and Deathspan. J Gerontol A Biol Sci Med Sci. 2022 08 12; 77(8):1479-1484. PMID: 35960854.
      Citations:    Fields:    Translation:Animals
    4. Nakagawa K, Chen R, Greenberg SM, Ross GW, Willcox BJ, Donlon TA, Allsopp RC, Willcox DC, Morris BJ, Masaki KH. Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage. J Hypertens. 2022 11 01; 40(11):2230-2235. PMID: 35943066.
      Citations: 2     Fields:    Translation:Humans
    5. Bruno MK, Watanabe G, Gao F, Seto T, Nakagawa K, Trinacty C, Brown S, Taira DA. Difference in rural and urban Medicare prescription pattern for Parkinson's disease in Hawai'i. Clin Park Relat Disord. 2022; 6:100144. PMID: 35521293.
      Citations:    
    6. Bruno MK, Watanabe G, Ishikawa K, Chen JJ, Gao F, Nakagawa K, Taira D. Geographic Variation in Prescription Patterns of Parkinson's Disease Medications. Mov Disord. 2022 03; 37(3):646-648. PMID: 34859504.
      Citations: 2     Fields:    Translation:Humans
    7. Martin CS, Lu N, Inouye DS, Nakagawa K, Ng K, Yu M, Hayashi MS. Delayed Respiratory Failure After Blunt Chest Trauma. Am Surg. 2021 Sep; 87(9):1468-1473. PMID: 33356435.
      Citations:    Fields:    Translation:Humans
    8. Hamahata NT, Nakagawa K. Regional Cerebral Hypoperfusion from Acute Subdural Hematoma. Neurocrit Care. 2020 04; 32(2):633-635. PMID: 31676926.
      Citations: 4     Fields:    Translation:Humans
    9. Chaffin HM, Nakagawa K, Koenig MA. Impact of Statewide Telestroke Network on Acute Stroke Treatment in Hawai'i. Hawaii J Health Soc Welf. 2019 09; 78(9):280-286. PMID: 31501825.
      Citations: 3     Fields:    Translation:Humans
    10. Lee JH, Zhang G, Harvey S, Nakagawa K. Temporal Trends of Hospitalization, Mortality, and Financial Impact Related to Preeclampsia with Severe Features in Hawai'i and the United States. Hawaii J Health Soc Welf. 2019 08; 78(8):252-257. PMID: 31463474.
      Citations: 4     Fields:    Translation:Humans
    11. Nakagawa K, Seto TB. Thrombus "Squeezing" Through Patent Foramen Ovale After Traumatic Brain Injury. Neurocrit Care. 2019 04; 30(2):490-491. PMID: 30446933.
      Citations:    Fields:    Translation:Humans
    12. Sempokuya T, Zhang G, Nakagawa K. Temporal trends of cirrhosis associated conditions. World J Hepatol. 2019 Jan 27; 11(1):74-85. PMID: 30705720.
      Citations:    
    13. Lam L, Ahn HJ, Okajima K, Schoenman K, Seto TB, Shohet RV, Miyamura J, Sentell TL, Nakagawa K. Gender Differences in the Rate of 30-Day Readmissions after Percutaneous Coronary Intervention for Acute Coronary Syndrome. Womens Health Issues. 2019 Jan - Feb; 29(1):17-22. PMID: 30482594.
      Citations: 7     Fields:    Translation:Humans
    14. Norisue Y, Fujimoto Y, Nakagawa K. Preliminary guideline- and pathophysiology-based protocols for neurocritical care. J Intensive Care. 2018; 6:45. PMID: 30094030.
      Citations:    
    15. Nakagawa K, King SL, Seto TB. Optimal Hematoma Volume Cut Points to Predict Functional Outcome After Basal Ganglia and Thalamic Hemorrhages. Front Neurol. 2018; 9:291. PMID: 29765352.
      Citations:    
    16. Nakagawa K, King SL, Seto TB, Mau MKLM. Disparities in Functional Outcome After Intracerebral Hemorrhage Among Asians and Pacific Islanders. Front Neurol. 2018; 9:186. PMID: 29651270.
      Citations:    
    17. Ideta TR, Lim E, Nakagawa K, Koenig MA. Racial and Ethnic Disparities in Hospital Mortality among Ischemic Stroke Patients in Hawaii. J Stroke Cerebrovasc Dis. 2018 Jun; 27(6):1458-1465. PMID: 29433932.
      Citations: 8     Fields:    Translation:Humans
    18. Taira D, Sentell T, Albright C, Lansidell D, Nakagawa K, Seto T, Stevens JM. Insights in Public Health: Ambulatory Blood Pressure Monitoring: Underuse in Clinical Practice in Hawai'i. Hawaii J Med Public Health. 2017 11; 76(11):314-317. PMID: 29164016.
      Citations: 2     Fields:    Translation:Humans
    19. Harvey SA, Lim E, Gandhi KR, Miyamura J, Nakagawa K. Racial-ethnic Disparities in Postpartum Hemorrhage in Native Hawaiians, Pacific Islanders, and Asians. Hawaii J Med Public Health. 2017 05; 76(5):128-132. PMID: 28484667.
      Citations: 6     Fields:    Translation:Humans
    20. Lum CJ, Nakagawa K, Shohet RV, Seto TB, Taira DA. The Cost-Benefit Balance of Statins in Hawai'i: A Moving Target. Hawaii J Med Public Health. 2017 04; 76(4):99-102. PMID: 28428922.
      Citations: 2     Fields:    Translation:Humans
    21. Allison RZ, Nakagawa K, Hayashi M, Donovan DJ, Koenig MA. Derivation of a Predictive Score for Hemorrhagic Progression of Cerebral Contusions in Moderate and Severe Traumatic Brain Injury. Neurocrit Care. 2017 02; 26(1):80-86. PMID: 27473209.
      Citations: 16     Fields:    Translation:Humans
    22. Nakagawa K, Ito CS, King SL. Ethnic Comparison of Clinical Characteristics and Ischemic Stroke Subtypes Among Young Adult Patients With Stroke in Hawaii. Stroke. 2017 01; 48(1):24-29. PMID: 27879449.
      Citations: 1     Fields:    Translation:Humans
    23. Nakagawa K, Galati AN. Ultra-early onset of ossification of the posterior longitudinal ligament with congenital rickets. Neurology. 2016 10 18; 87(16):1738-1740. PMID: 27629093.
      Citations: 2     Fields:    Translation:Humans
    24. Nakagawa K, Ahn HJ, Taira DA, Miyamura J, Sentell TL. Ethnic Comparison of 30-Day Potentially Preventable Readmissions After Stroke in Hawaii. Stroke. 2016 10; 47(10):2611-7. PMID: 27608816.
      Citations: 8     Fields:    Translation:Humans
    25. Nakagawa K, Lim E, Harvey S, Miyamura J, Juarez DT. Racial/Ethnic Disparities in the Association Between Preeclampsia Risk Factors and Preeclampsia Among Women Residing in Hawaii. Matern Child Health J. 2016 09; 20(9):1814-24. PMID: 27000850.
      Citations: 14     Fields:    Translation:Humans
    26. Moran JL, Nakagawa K, Asai SM, Koenig MA. 24/7 Neurocritical Care Nurse Practitioner Coverage Reduced Door-to-Needle Time in Stroke Patients Treated with Tissue Plasminogen Activator. J Stroke Cerebrovasc Dis. 2016 May; 25(5):1148-1152. PMID: 26907680.
      Citations: 9     Fields:    Translation:Humans
    27. Galati A, King SL, Nakagawa K. Gender Disparities among Intracerebral Hemorrhage Patients from a Multi-ethnic Population. Hawaii J Med Public Health. 2015 Sep; 74(9 Suppl 2):12-5. PMID: 26793409.
      Citations: 4     Fields:    Translation:Humans
    28. Linton KF, Ing MM, Vento MA, Nakagawa K. From discharge planner to "concierge": recommendations for hospital social work by clients with intracerebral hemorrhage. Soc Work Public Health. 2015; 30(6):486-95. PMID: 26252181.
      Citations: 2     Fields:    Translation:Humans
    29. Shaw KM, Gallek MJ, Sheppard KG, Ritter L, Vento MA, Asai SM, Nakagawa K. Ethnic Differences in Withdrawal of Life Support After Intracerebral Hemorrhage. Hawaii J Med Public Health. 2015 Jun; 74(6):203-9. PMID: 26114075.
      Citations: 2     Fields:    Translation:Humans
    30. Ing MM, Linton KF, Vento MA, Nakagawa K. Investigation of Stroke Needs (INVISION) Study: Stroke Awareness and Education. Hawaii J Med Public Health. 2015 Apr; 74(4):141-5. PMID: 25954601.
      Citations: 1     Fields:    Translation:Humans
    31. Nakagawa K, Vento MA, Ing MM, Seto TB. Racial disparities in methamphetamine-associated intracerebral hemorrhage. Neurology. 2015 Mar 10; 84(10):995-1001. PMID: 25663228.
      Citations: 7     Fields:    Translation:Humans
    32. Nakagawa K, Galati A, Juarez DT. The excess cost of interisland transfer of intracerebral hemorrhage patients. Am J Emerg Med. 2015 Apr; 33(4):512-5. PMID: 25624077.
      Citations: 3     Fields:    Translation:Humans
    33. Nakagawa K, MacDonald PR, Asai SM. Stroke Disparities: Disaggregating Native Hawaiians from other Pacific Islanders. Ethn Dis. 2015; 25(2):157-61. PMID: 26118142.
      Citations: 4     Fields:    Translation:Humans
    34. Chu C, Tokumaru S, Izumi K, Nakagawa K. Obesity increases risk of anticoagulation reversal failure with prothrombin complex concentrate in those with intracranial hemorrhage. Int J Neurosci. 2016; 126(1):62-6. PMID: 25430740.
      Citations: 3     Fields:    Translation:Humans
    35. Nakagawa K, Vento MA, Ing MM, Asai SM. Impact of diabetes on prolonged hospital stay among Native Hawaiians and other Pacific Islanders with ischemic stroke. Hawaii J Med Public Health. 2014 Dec; 73(12 Suppl 3):4-7. PMID: 25535594.
      Citations: 1     Fields:    Translation:Humans
    36. Ing MM, Vento MA, Nakagawa K, Linton KF. A qualitative study of transportation challenges among intracerebral hemorrhage survivors and their caregivers. Hawaii J Med Public Health. 2014 Nov; 73(11):353-7. PMID: 25414805.
      Citations: 3     Fields:    Translation:Humans
    37. Nakagawa K, Lee SB. Predominant intraventricular hemorrhage from a ruptured posterior communicating artery aneurysm. Neurohospitalist. 2014 Jul; 4(3):164. PMID: 24982722.
      Citations:    
    38. Nakagawa K, Obana KK. Willingness to favor aggressive care and live with disability following severe traumatic brain injury: a survey of healthy young adults in Hawai'i. Hawaii J Med Public Health. 2014 Jul; 73(7):212-6. PMID: 25089232.
      Citations:    Fields:    Translation:Humans
    39. Koenig MA, Holt JL, Ernst T, Buchthal SD, Nakagawa K, Stenger VA, Chang L. MRI default mode network connectivity is associated with functional outcome after cardiopulmonary arrest. Neurocrit Care. 2014 Jun; 20(3):348-57. PMID: 24464830.
      Citations: 35     Fields:    Translation:Humans
    40. Nakagawa K, Vento MA, Seto TB, Koenig MA, Asai SM, Chang CW, Hemphill JC. Sex differences in the use of early do-not-resuscitate orders after intracerebral hemorrhage. Stroke. 2013 Nov; 44(11):3229-31. PMID: 23982712.
      Citations: 17     Fields:    Translation:Humans
    41. Nakagawa K, Hoshide RR, Asai SM, Johnson KG, Beniga JG, Albano MC, del Castillo JL, Donovan DJ, Chang CW, Koenig MA. Favorable outcomes for Native Hawaiians and other Pacific Islanders with severe traumatic brain injury. Hawaii J Med Public Health. 2013 Apr; 72(4):129-35. PMID: 23795313.
      Citations: 2     Fields:    Translation:Humans
    42. Nakagawa K, Koenig MA, Asai SM, Chang CW, Seto TB. Disparities among Asians and native Hawaiians and Pacific Islanders with ischemic stroke. Neurology. 2013 Feb 26; 80(9):839-43. PMID: 23365055.
      Citations: 16     Fields:    Translation:Humans
    43. Nakagawa K, Koenig MA, Seto TB, Asai SM, Chang CW. Racial disparities among Native Hawaiians and Pacific Islanders with intracerebral hemorrhage. Neurology. 2012 Aug 14; 79(7):675-80. PMID: 22815551.
      Citations: 20     Fields:    Translation:Humans
    44. Nakagawa K, Chang CW, Koenig MA, Yu M, Tokumaru S. Treatment of refractory intracranial hypertension with 23.4% saline in children with severe traumatic brain injury. J Clin Anesth. 2012 Jun; 24(4):318-23. PMID: 22608588.
      Citations: 4     Fields:    Translation:Humans
    45. Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC, Smith WS. Accuracy of neurovascular fellows' prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012 Mar; 43(3):702-7. PMID: 22223238.
      Citations: 12     Fields:    Translation:Humans
    46. Nakagawa K, Smith WS. Evaluation and management of increased intracranial pressure. Continuum (Minneap Minn). 2011 Oct; 17(5 Neurologic Consultation in the Hospital):1077-93. PMID: 22809983.
      Citations: 2     Fields:    
    47. Nakagawa K, Serrador JM, LaRose SL, Sorond FA. Dynamic cerebral autoregulation after intracerebral hemorrhage: A case-control study. BMC Neurol. 2011 Aug 31; 11:108. PMID: 21884574.
      Citations: 24     Fields:    Translation:Humans
    48. Nakagawa K, Hills NK, Kamel H, Patel PV, Manley GT, Hemphill JC. The effect of decompressive hemicraniectomy on brain temperature after severe brain injury. Neurocrit Care. 2011 Aug; 15(1):101-6. PMID: 21061187.
      Citations: 4     Fields:    Translation:Humans
    49. Nakagawa K, Smith WS. Paradoxical vasoconstrictive effect in the contralateral hemisphere after carotid stenting. Neurology. 2011 Jul 19; 77(3):300. PMID: 21768600.
      Citations:    Fields:    Translation:Humans
    50. Nakagawa K, Tang JF. Physiologic response of human brain death and the use of vasopressin for successful organ transplantation. J Clin Anesth. 2011 Mar; 23(2):145-8. PMID: 21377081.
      Citations: 2     Fields:    Translation:Humans
    51. Kamel H, Navi BB, Nakagawa K, Hemphill JC, Ko NU. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials. Crit Care Med. 2011 Mar; 39(3):554-9. PMID: 21242790.
      Citations: 91     Fields:    Translation:Humans
    52. Deegan BM, Serrador JM, Nakagawa K, Jones E, Sorond FA, Olaighin G. The effect of blood pressure calibrations and transcranial Doppler signal loss on transfer function estimates of cerebral autoregulation. Med Eng Phys. 2011 Jun; 33(5):553-62. PMID: 21239208.
      Citations: 11     Fields:    Translation:Humans
    53. Dhand A, Nakagawa K, Nagpal S, Gelfand JM, Kim AS, Smith WS, Tihan T. Cardiac rupture after intravenous t-PA administration in acute ischemic stroke. Neurocrit Care. 2010 Oct; 13(2):261-2. PMID: 20697837.
      Citations: 10     Fields:    Translation:Humans
    54. Nakagawa K, Bianchi MT, Nakagawa SS, Sorond FA. Aggressive care after a massive stroke in young patients: is that what they want? Neurocrit Care. 2010 Aug; 13(1):118-22. PMID: 20182921.
      Citations: 13     Fields:    Translation:Humans
    55. Nakagawa K, Serrador JM, Larose SL, Moslehi F, Lipsitz LA, Sorond FA. Autoregulation in the posterior circulation is altered by the metabolic state of the visual cortex. Stroke. 2009 Jun; 40(6):2062-7. PMID: 19359628.
      Citations: 22     Fields:    Translation:HumansCells
    56. Nakagawa K, Sorond FA, Ropper AH. Ultra-early magnetic resonance imaging findings of eclampsia. Arch Neurol. 2008 Jul; 65(7):974-6. PMID: 18625869.
      Citations: 2     Fields:    Translation:Humans
    57. Nakagawa K, Sheikh SI, Snuderl M, Frosch MP, Greenberg SM. A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. J Neurol Sci. 2008 Sep 15; 272(1-2):186-90. PMID: 18579156.
      Citations: 13     Fields:    Translation:Humans
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