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Jonathan Yap

Title
Faculty RankPostdoctoral
InstitutionUniversity of Hawaii at Manoa
DepartmentMedicine
AddressJohn A. Burns School of Medicine
University of Hawaii at Manoa
663 Ilalo Street
Honolulu HI 96813
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    Collapse Research 
    Collapse research activities and funding
    F31HL139082     (YAP, JONATHAN)Sep 1, 2017 - May 10, 2019
    NIH
    Over-expression of Chitotriosidase Modulates Macrophage Function and Progression of Atherosclerosis in Hyperlipidemic, LDLr-/- Mice
    Role: Principal Investigator
    K99HL168433     (YAP, JONATHAN)Jun 1, 2023 - May 31, 2025
    NIH
    Anti-inflammatory Signaling of RNA-binding Protein, Tristetraprolin, During Myocardial Infarction
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bhatty A, Wilkinson C, Batra G, Aktaa S, Smith AB, Wahab A, Chappell S, Alfredsson J, Erlinge D, Ferreira J, Gu?mundsd?ttir IJ, Hrafnkelsd?ttir ?J, Ingimarsd?ttir IJ, Irs A, J?nosi A, J?rai Z, Oliveira-Santos M, Popescu BA, Vasko P, Vinereanu D, Yap J, Bugiardini R, Cenko E, Nadarajah R, Sydes MR, James S, Maggioni AP, Wallentin L, Casadei B, Gale CP. Standardized and hierarchically classified heart failure and complementary disease monitoring outcome measures: European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart). Eur Heart J Qual Care Clin Outcomes. 2025 Nov 04; 11(7):900-909. PMID: 39384575.
      Citations: 1     Fields:    
    2. Cabrera-Fuentes HA, Ruiz-Meana M, Barreto G, Serebruany VL, S?nchez-Vega JT, P?rez-Campos E, Kostin S, B?ning A, Jarqu?n Gonz?lez EE, Al-Suhaimi EA, Rodriguez-Montesinos J, Inserte J, Pedretti S, Yap J, Irei J, Sedding DG, Lecour S, Liehn EA, Garcia-Dorado D, Hausenloy DJ, Boisvert WA, Preissner KT. Extracellular RNA drives TNF-a/TNF-receptor-1 mediated cardiac ischemia/reperfusion injury: Mechanistic insights and therapeutic potential of RNase1. Pharmacol Res. 2025 Nov; 221:107944. PMID: 40946941.
      Citations:    Fields:    
    3. Raja Shariff RE, Putri VKP, Gan G, Loh JK, Lee DPH, Sari NY, Evangelista LKM, Cruz RR, Yap J. How Does Heart Failure Fellowship Training Influence Future Clinical Practice? An Asia-Pacific Survey. Int J Heart Fail. 2025 Jul; 7(3):196-200. PMID: 40766190.
      Citations:    
    4. Cuenza L, Honda S, Fong KY, Sawano M, Cader FA, Surunchupakorn P, Widodo WA, Dalakoti M, Kang J, Chimura M, Al-Omary M, Lee ZV, Sari NY, Suesat T, Ahmad T, Magno JD, Tan CT, Tiksnadi BB, Hewarathna U, Habib F, Lee DPH, Yap J. Variations in management strategies for stable coronary artery disease in the Asia-Pacific region: Insights from a multinational survey. Ann Acad Med Singap. 2025 May 22; 54(5):283-295. PMID: 40471110.
      Citations:    Fields:    Translation:Humans
    5. Ji H, Wang X, Sia CH, Yap J, Lim ST, Djohan AH, Chang Y, Zhang N, Guo M, Li F, Lim ZW, Wang YX, Sheng B, Wong TY, Cheng S, Yeo KK, Tham YC. Large language model comparisons between English and Chinese query performance for cardiovascular prevention. Commun Med (Lond). 2025 May 16; 5(1):177. PMID: 40379850.
      Citations:    
    6. So KC, Yap J, Song GY, Poon K, Sung SH, Chandavimol M, Hayashida K, Park DW, Ewe SH, Chen M, Hei-Tung Chan V, Iwata J, Tangcharoen T, Tern P, Park HS, Alasnag M, Ohno Y, Hon JKF, Bhagwandeen R, Tabata M, Lee AP, Jilaihawi H, Wang DD, Tang GHL, Lim DS, Modine T, Lam YY. Epidemiology of Valvular Heart Disease in Asia Pacific Region. JACC Asia. 2025 May 03. PMID: 40396937.
      Citations:    
    7. Wee LE, Loy EX, Lim JT, Chia YW, Lim SL, Yap J, Yeo KK, Hausenloy DJ, Chan MYY, Lye DCB, Tan KB. Omicron SARS-CoV-2 outcomes in vaccinated individuals with heart failure and ischaemic heart disease. Ann Acad Med Singap. 2025 Apr 30; 54(5):270-282. PMID: 40471109.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    8. Dalakoti M, Lin NHY, Yap J, Cader A, Dipanker P, Lee D, Raja Shariff RE, Cuenza L, Honda S, Malis V, Jiang H, Hirachan A, Chimura M, Yeo TJ, Yeo KK, Jack Wei Chieh T, Tromp J, Loh PH, Chew NWS, Wong S, Sia CH, Tan BYQ, Johar S, Lip GYH, Yang E, Virani SS, Hageman S, Liu H, Di Angelantonio E, Dorairaj P, Koh AS, Chin C, Al Mahmeed W, Chan MY, Foo R. Primary Prevention of Cardiovascular?Disease in Asia: Opportunities and?Solutions: A Narrative Review. JACC Adv. 2025 Apr; 4(4):101676. PMID: 40120215.
      Citations:    
    9. Dalakoti M, Lin NHY, Yap J, Cader A, Dipanker P, Lee D, Raja Shariff RE, Cuenza L, Honda S, Malis V, Jiang H, Hirachan A, Chimura M, Yeo TJ, Yeo KK, Tan JWC, Tromp J, Loh PH, Chew NWS, Wong S, Sia CH, Tan BYQ, Johar S, Lip GYH, Yang E, Virani SS, Hageman S, Liu H, Di Angelantonio E, Dorairaj P, Koh AS, Chin C, Al Mahmeed W, Chan MY, Foo R. Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review. JACC Adv. 2025 Apr; 4(4):101670. PMID: 40117691.
      Citations:    
    10. Loh EW, Huang W, Sultana R, Kong SC, Ng CJ, Tan SY, Chin C, Yap JJL, Yeo KK. Association of blood pressure and left ventricular mass with subclinical coronary atherosclerosis. Open Heart. 2025 Feb 11; 12(1). PMID: 39933828.
      Citations:    Fields:    Translation:Humans
    11. Wilkinson C, Bhatty A, Batra G, Aktaa S, Smith AB, Dwight J, Rucinski M, Chappell S, Alfredsson J, Erlinge D, Ferreira J, Gu?mundsd?ttir IJ, Hrafnkelsd?ttir ?J, Ingimarsd?ttir IJ, Irs A, J?nosi A, J?rai Z, Oliveira-Santos M, Popescu BA, Vasko P, Vinereanu D, Yap J, Bugiardini R, Cenko E, Nadarajah R, Sydes MR, James S, Maggioni AP, Wallentin L, Casadei B, Gale CP. Definitions of clinical study outcome measures for cardiovascular diseases: the European Unified Registries for Heart Care Evaluation and Randomized Trials (EuroHeart). Eur Heart J. 2025 Jan 07; 46(2):190-214. PMID: 39545867.
      Citations: 4     Fields:    Translation:Humans
    12. Fong KY, Koh JMY, Saw LW, Anggreni D, Ng EZX, Chan YH, Poon K, Stub D, Sung SH, Chandavimol M, Lee MK, Chui ASF, Gopalamurugan AB, Nair R, Guo Y, Amanullah MR, Chao VTT, Ewe SH, Ho KW, Yap J. Clinical Outcomes of Transcatheter Mitral Valve-In-Valve and Valve-In-Ring Implantation: A Systematic Review and Meta-Analysis. Catheter Cardiovasc Interv. 2025 01; 105(1):219-238. PMID: 39568133.
      Citations: 1     Fields:    Translation:Humans
    13. Yap J, Hayashida K, Lee MKY, Stub D, Hon JKF, Ho KW, Lo S, Seth A, Kim HS, Wongpraparut N, Nguyen QN, Dy TC, Chandavimol M, Ewe SH, Yin WH, Lee YT, Tay EL, Poon K, Chen M, Chui A, Lam SC, Rao RS, Izumo M, Nair R, Tang GH, Tabata M, Yahaya SA, Sin KY, Park DW, Wang J, Chieh JTW. Asian Pacific Society of Cardiology Position Statement on the Use of Transcatheter Aortic Valve Implantation in the Management of Aortic Stenosis. JACC Asia. 2024 Dec; 4(12):885-897. PMID: 39802986.
      Citations:    
    14. Bhatty A, Wilkinson C, Batra G, Alfredsson J, Erlinge D, Ferreira J, Gu?mundsd?ttir IJ, Hrafnkelsd?ttir ?J, Ingimarsd?ttir IJ, Irs A, J?rai Z, J?nosi A, Popescu BA, Santos M, Vasko P, Vinereanu D, Yap J, Maggioni AP, Wallentin L, Casadei B, Gale CP. Cohort profile: the European Unified Registries On Heart Care Evaluation and Randomized Trials (EuroHeart)-acute coronary syndrome and percutaneous coronary intervention. Eur Heart J Qual Care Clin Outcomes. 2024 Aug 08; 10(5):386-390. PMID: 38609345.
      Citations: 1     Fields:    Translation:Humans
    15. Gorny AW, Prakaash S, Neo JW, Chow W, Yeo KK, Yap J, M?ller-Riemenschneider F. Longitudinal change in cardiorespiratory fitness and the association with cardiovascular disease and all-cause mortality in young Asian men: a cohort study. BMJ Open Sport Exerc Med. 2024; 10(3):e001986. PMID: 39286322.
      Citations:    
    16. Goh RSJ, Chong B, Jayabaskaran J, Jauhari SM, Chan SP, Kueh MTW, Shankar K, Li H, Chin YH, Kong G, Anand VV, Chan KA, Sukmawati I, Toh SA, Muthiah M, Wang JW, Tse G, Mehta A, Fong A, Baskaran L, Zhong L, Yap J, Yeo KK, Hausenloy DJ, Tan JWC, Chao TF, Li YH, Lim SL, Chan KH, Loh PH, Chai P, Yeo TC, Low AF, Lee CH, Foo R, Tan HC, Yip J, Rao S, Honda S, Yasuda S, Kajiya T, Goto S, Yan BP, Zhou X, Figtree GA, Mamas MA, Kim Y, Jeong YH, Kim MH, Park DW, Park SJ, Richards AM, Chan MY, Lip GYH, Chew NWS. The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions. Lancet Reg Health West Pac. 2024 Aug; 49:101138. PMID: 39100533.
      Citations:    
    17. Wee LE, Lim JT, Tay AT, Pang D, Chiew CJ, Chia YW, Lim SL, Yap J, Ong B, Lye DCB, Tan KB. Long-term cardiovascular, cerebrovascular, and thrombotic complications after SARS-CoV-2-Omicron infection: a retrospective cohort study. Clin Microbiol Infect. 2024 Oct; 30(10):1319-1326. PMID: 38908748.
      Citations: 5     Fields:    Translation:HumansCells
    18. Tham MY, Chan CL, Toh D, Poh J, Lim A, Soh S, Peck LF, Foo B, Ng A, Ng P, Ang PS, Dorajoo S, Teo D, Lim TW, Lim YT, Choo J, Ding ZP, Yeo KK, Yap J, Tan HX. An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore. Singapore Med J. 2024 Feb 16. PMID: 38363732.
      Citations:    Fields:    
    19. Fong KY, Low CHX, Chan YH, Ho KW, Keh YS, Chin CT, Chin CY, Fam JM, Wong N, Idu M, Wong ASL, Lim ST, Koh TH, Tan JWC, Yeo KK, Yap J. Role of Invasive Strategy for Non-ST-Elevation Myocardial Infarction in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Am J Cardiol. 2023 10 15; 205:369-378. PMID: 37639763.
      Citations: 1     Fields:    Translation:Humans
    20. Fong KY, Ong JHW, Chan YH, Yap J, Ho KW, Aslim EJ, Ng LG, Gan VHL, Lim EJ. A Systematic Review and Meta-Analysis of Transcatheter Versus Surgical Aortic Valve Replacement in Kidney Transplant Patients. Am J Cardiol. 2023 10 01; 204:22-25. PMID: 37536199.
      Citations:    Fields:    Translation:Humans
    21. Sahl?n AO, Jiang H, Lau YH, Cuenza L, Cader FA, Al-Omary M, Surunchupakorn P, Ho KH, Sung J, Lee D, Honda S, Tan Wei Chieh J, Yap J. Direct Oral Anticoagulation Versus Warfarin in Left Ventricular Thrombus: Pooled Analysis of Randomized Controlled Trials. J Clin Pharmacol. 2023 10; 63(10):1101-1107. PMID: 37139934.
      Citations: 1     Fields:    Translation:Humans
    22. Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert WA, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy SV, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. PLoS Pathog. 2023 05; 19(5):e1011409. PMID: 37200377.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    23. Fong KY, Yap JJL, Chan YH, Ewe SH, Chao VTT, Amanullah MR, Govindasamy SP, Aziz ZA, Tan VH, Ho KW. Network Meta-Analysis Comparing Transcatheter, Minimally Invasive, and Conventional Surgical Aortic Valve Replacement. Am J Cardiol. 2023 05 15; 195:45-56. PMID: 37011554.
      Citations: 1     Fields:    Translation:Humans
    24. Gorny AW, Yap J, Neo JW, Chow WE, Yeo KK, Tan CS, M?ller-Riemenschneider F. Cardiorespiratory fitness, body mass index, cardiovascular disease, and mortality in young men: A cohort study. Front Public Health. 2023; 11:1076065. PMID: 36875358.
      Citations: 3     Fields:    Translation:Humans
    25. Yap J, Irei J, Lozano-Gerona J, Vanapruks S, Bishop T, Boisvert WA. Macrophages in cardiac remodelling after myocardial infarction. Nat Rev Cardiol. 2023 06; 20(6):373-385. PMID: 36627513.
      Citations: 97     Fields:    Translation:HumansCells
    26. Wong MYZ, Yap JJL, Chih HJ, Yan BPY, Fong AYY, Beltrame JF, Wijaya IP, Nguyen HTT, Brennan AL, Reid CM, Yeo KK. Regional differences in percutaneous coronary intervention outcomes in STEMI patients with diabetes: The Asia-Pacific evaluation of cardiovascular therapies (ASPECT) collaboration. Int J Cardiol. 2023 Jan 15; 371:84-91. PMID: 36220505.
      Citations: 2     Fields:    Translation:Humans
    27. Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert W, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy S, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. bioRxiv. 2022 Sep 22. PMID: 36172118.
      Citations:    
    28. Zhou W, Chan YE, Foo CS, Zhang J, Teo JX, Davila S, Huang W, Yap J, Cook S, Tan P, Chin CW, Yeo KK, Lim WK, Krishnaswamy P. High-Resolution Digital Phenotypes From Consumer Wearables and Their Applications in Machine Learning of Cardiometabolic Risk Markers: Cohort Study. J Med Internet Res. 2022 07 29; 24(7):e34669. PMID: 35904853.
      Citations: 9     Fields:    Translation:Humans
    29. Chiou A, Yap J, Russo S, Stripe BR, Wong GB, Southard JA. Understanding repeat hospitalizations in intermediate-to-high risk aortic stenosis patients following transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2022 03; 99(4):1188-1196. PMID: 35019207.
      Citations: 1     Fields:    Translation:Humans
    30. Yap J, Anbalakan K, Tay WT, Ting D, Cheung CY, Sabanayagam C, Cheng CY, Wong TY, Yeo KK. Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population. BMJ Open Diabetes Res Care. 2021 07; 9(1). PMID: 34244217.
      Citations:    
    31. Tay E, Khaing T, Yin WH, Posas EF, Kao PH, Buddhari W, Hayashida K, Ho KW, Lin MS, Yap J, Zhang JJ, Chiam PTL, Rosli MA, Park SJ, Udayacherm W, Yanagisawa R, Tan HC, Lee MKY. Asia Pacific TAVI registry (an APSIC initiative): initial report of early outcomes: Asia Pacific TAVI registry. AsiaIntervention. 2021 Jul; 7(1):54-59. PMID: 34913003.
      Citations:    
    32. Ding C, Egli L, Bosco N, Sun L, Goh HJ, Yeo KK, Yap JJL, Actis-Goretta L, Leow MK, Magkos F. Plasma Branched-Chain Amino Acids Are Associated With Greater Fasting and Postprandial Insulin Secretion in Non-diabetic Chinese Adults. Front Nutr. 2021; 8:664939. PMID: 33996878.
      Citations:    
    33. Lim Y, Gochuico CFS, D'Ascenzo F, Ho KW, Lin MS, Gil IJN, Ielasi A, Tespili M, Mej?a AC, DePaoli A, Yap J, Kao HL, Lee MK, Tay E. Assessing the Impact of Transcatheter Aortic Valve Implantation on Cardiac Catheterisation: A Multicentric Study. Heart Lung Circ. 2021 Sep; 30(9):1397-1405. PMID: 33812787.
      Citations: 1     Fields:    Translation:Humans
    34. Teng TK, Tay WT, Richards AM, Chew TSM, Anand I, Ouwerkerk W, Chandramouli C, Huang W, Lawson CA, Kadam UT, Yap J, Lim S, Hung CL, MacDonald MR, Loh SY, Shimizu W, Tromp J, Lam CSP. Socioeconomic Status and Outcomes in Heart Failure With Reduced Ejection Fraction From Asia. Circ Cardiovasc Qual Outcomes. 2021 04; 14(4):e006962. PMID: 33757307.
      Citations: 17     Fields:    Translation:Humans
    35. Chyou JY, Tay WT, Anand IS, Teng TK, Yap JJL, MacDonald MR, Chopra V, Loh SY, Shimizu W, Abidin IZ, Richards AM, Butler J, Lam CSP. Electroanatomic Ratios and Mortality in Patients With Heart Failure: Insights from the ASIAN-HF Registry. J Am Heart Assoc. 2021 03 16; 10(6):e017932. PMID: 33719492.
      Citations: 3     Fields:    Translation:Humans
    36. Yap J, Chew DP, Stone GW, Tan JWC. Pharmacotherapy in Stable Coronary Artery Disease: Historical Perspectives and New Insights from the ISCHEMIA Trial. Eur Cardiol. 2021 Feb; 16:e04. PMID: 33737958.
      Citations:    
    37. Yap J, Rogers JH, Aman E, Smith TWR, Singh GD. MitraClip Implantation Guided by Volumetric Intracardiac Echocardiography: Technique and Feasibility in Patients Intolerant to Transesophageal Echocardiography. Cardiovasc Revasc Med. 2021 07; 28S:85-88. PMID: 33541810.
      Citations: 5     Fields:    Translation:Humans
    38. Tan ESJ, Chan SP, Liew OW, Chong JPC, Leong GKT, Yeo DPS, Ong HY, Jaufeerally F, Yap J, Sim D, Ng TP, Ling LH, Lam CSP, Richards AM. Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure. Clin Chem. 2021 01 08; 67(1):216-226. PMID: 33279970.
      Citations: 12     Fields:    Translation:Humans
    39. Jin GR, Zhang YL, Yap J, Boisvert WA, Lee BH. Hair growth potential of Salvia plebeia extract and its associated mechanisms. Pharm Biol. 2020 Dec; 58(1):400-409. PMID: 32420784.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    40. Yap J, McCurdy S, Alcala M, Irei J, Garo J, Regan W, Lee BH, Kitamoto S, Boisvert WA. Expression of Chitotriosidase in Macrophages Modulates Atherosclerotic Plaque Formation in Hyperlipidemic Mice. Front Physiol. 2020; 11:714. PMID: 32655419.
      Citations:    
    41. Tan ESJ, Goh V, Santema BT, Tay WT, Teng TK, Yap J, Tromp J, Hung CL, Chopra V, Anand I, MacDonald MR, Ling LH, Van Gelder IC, Rienstra M, Voors AA, Richards AM, Lam CSP. Ethnic differences in atrial fibrillation among patients with heart failure in Asia. ESC Heart Fail. 2020 08; 7(4):1419-1429. PMID: 32383559.
      Citations: 5     Fields:    Translation:Humans
    42. Cong S, Ramachandra CJA, Mai Ja KM, Yap J, Shim W, Wei L, Hausenloy DJ. Mechanisms underlying diabetic cardiomyopathy: From pathophysiology to novel therapeutic targets. Cond Med. 2020 Apr; 3(2):82-97. PMID: 34169234.
      Citations:    
    43. Yap J, Chen S, Smith TWR, Rogers JH, Singh GD. Transjugular mitral valve repair with the MitraClip: A step-by-step guide. Catheter Cardiovasc Interv. 2020 09 01; 96(3):699-705. PMID: 32259371.
      Citations: 3     Fields:    Translation:Humans
    44. Yap J, Keh YS, Shen T, Lam CSP, Chia SY, Jaufeerally FR, Ong W, Sim D, Ching CK. QRS duration and cardiovascular mortality in Asian patients with heart failure and preserved and reduced ejection fraction. Cardiol J. 2021; 28(1):166-169. PMID: 32207835.
      Citations: 2     Fields:    Translation:Humans
    45. MacDonald MR, Tay WT, Teng TK, Anand I, Ling LH, Yap J, Tromp J, Wander GS, Naik A, Ngarmukos T, Siswanto BB, Hung CL, Richards AM, Lam CSP. Regional Variation of Mortality in Heart Failure With Reduced and Preserved Ejection Fraction Across Asia: Outcomes in the ASIAN-HF Registry. J Am Heart Assoc. 2020 01 07; 9(1):e012199. PMID: 31852421.
      Citations: 61     Fields:    Translation:Humans
    46. Yeo KK, Ong HY, Chua T, Lim ZJ, Yap J, Ho HH, Jaufeerally F, Tong KL, Kojodjojo P, Wong HB, Heng D, Tan KB, Richards AM, Teoh KL, Sin K, Tan NC, Lee SBM, Lim T, Ta A, Liok E, Lau YH, Gao F, Liman C, Sarkar J, Sahl?n A, Koh TH, Chan MY. Building a Longitudinal National Integrated Cardiovascular Database - Lessons Learnt From SingCLOUD. Circ Rep. 2019 Dec 07; 2(1):33-43. PMID: 33693172.
      Citations:    
    47. Yap J, Lim WK, Sahl?n A, Chin CW, Chew KMY, Davila S, Allen J, Goh V, Tan SY, Tan P, Lam CSP, Cook SA, Yeo KK. Harnessing technology and molecular analysis to understand the development of cardiovascular diseases in Asia: a prospective cohort study (SingHEART). BMC Cardiovasc Disord. 2019 11 21; 19(1):259. PMID: 31752689.
      Citations: 8     Fields:    Translation:Humans
    48. Noviani M, Saffari SE, Tan JL, Yip JWL, Teng GG, Law WG, Chan GYL, Santosa A, Lim AYN, Hong C, Ng SA, Tay ELW, Ruan W, Yap J, Low AHL. Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort. Semin Arthritis Rheum. 2020 06; 50(3):473-479. PMID: 31810742.
      Citations: 12     Fields:    Translation:Humans
    49. Teo JX, Davila S, Yang C, Hii AA, Pua CJ, Yap J, Tan SY, Sahl?n A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK, Tan P, Lim WK. Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging. Commun Biol. 2019; 2:361. PMID: 31602410.
      Citations:    
    50. Chong J, Ho AF, Yap J, Bulluck H, Hausenloy DJ. Is there a role for remote ischemic conditioning in preventing 5-fluorouracil-induced coronary vasospasm? Cond Med. 2019 Oct; 2(5):204-212. PMID: 32133437.
      Citations:    
    51. Lin YH, Yap J, Ramachandra CJA, Hausenloy DJ. New insights provided by myofibril mechanics in inherited cardiomyopathies. Cond Med. 2019 Oct; 2(5):213-224. PMID: 32133438.
      Citations:    
    52. Chandramouli C, Tay WT, Bamadhaj NS, Tromp J, Teng TK, Yap JJL, MacDonald MR, Hung CL, Streng K, Naik A, Wander GS, Sawhney J, Ling LH, Richards AM, Anand I, Voors AA, Lam CSP. Association of obesity with heart failure outcomes in 11 Asian regions: A cohort study. PLoS Med. 2019 09; 16(9):e1002916. PMID: 31550265.
      Citations: 63     Fields:    Translation:Humans
    53. Yap J, Ewe SH, Chao V, Ho KW. Can Lightning Strike Twice? Tackling Complications From Transcatheter Aortic Valve Implantation. J Invasive Cardiol. 2019 Sep; 31(9):E277. PMID: 31478897.
      Citations:    Fields:    Translation:Humans
    54. Yap J, Tay WT, Teng TK, Anand I, Richards AM, Ling LH, MacDonald MR, Chandramouli C, Tromp J, Siswanto BB, Zile M, McMurray J, Lam CSP. Association of Diabetes Mellitus on Cardiac Remodeling, Quality of Life, and Clinical Outcomes in Heart Failure With Reduced and Preserved Ejection Fraction. J Am Heart Assoc. 2019 09 03; 8(17):e013114. PMID: 31431116.
      Citations: 55     Fields:    Translation:Humans
    55. Tromp J, Lim SL, Tay WT, Teng TK, Chandramouli C, Ouwerkerk W, Wander GS, Sawhney JPS, Yap J, MacDonald MR, Ling LH, Sattar N, McMurray JJV, Richards AM, Anand I, Lam CSP. Microvascular Disease in Patients With Diabetes With Heart Failure and Reduced Ejection Versus Preserved Ejection Fraction. Diabetes Care. 2019 09; 42(9):1792-1799. PMID: 31292141.
      Citations: 45     Fields:    Translation:Humans
    56. Tan ES, Chan SP, Xu CF, Yap J, Richards AM, Ling LH, Sim D, Jaufeerally F, Yeo D, Loh SY, Ong HY, Leong KTG, Ng TP, Nyunt SZ, Feng L, Okin P, Lam CS, Lim TW. Cornell product is an ECG marker of heart failure with preserved ejection fraction. Heart Asia. 2019; 11(1):e011108. PMID: 31244913.
      Citations:    
    57. Yap J, Cabrera-Fuentes HA, Irei J, Hausenloy DJ, Boisvert WA. Role of Macrophages in Cardioprotection. Int J Mol Sci. 2019 May 19; 20(10). PMID: 31109146.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    58. Chia YMF, Teng TK, Tay WT, Anand I, MacDonald MR, Yap J, Chandramouli C, Richards AM, Tromp J, Ouwerkerk W, Ling LH, Lam CSP. Prescription patterns of anti-diabetic medications and clinical outcomes in Asian patients with heart failure and diabetes mellitus. Eur J Heart Fail. 2019 05; 21(5):685-688. PMID: 31033098.
      Citations: 5     Fields:    Translation:Humans
    59. Yap J, Ng Y, Yeo KK, Sahl?n A, Lam CSP, Lee V, Ma S. Particulate air pollution on cardiovascular mortality in the tropics: impact on the elderly. Environ Health. 2019 04 18; 18(1):34. PMID: 30999903.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    60. Go YY, Sellmair R, Allen JC, Sahl?n A, Bulluck H, Sim D, Jaufeerally FR, MacDonald MR, Lim ZY, Chai P, Loh SY, Yap J, Lam CSP. Defining a 'frequent admitter' phenotype among patients with repeat heart failure admissions. Eur J Heart Fail. 2019 03; 21(3):311-318. PMID: 30549171.
      Citations: 4     Fields:    Translation:Humans
    61. Tromp J, MacDonald MR, Tay WT, Teng TK, Hung CL, Narasimhan C, Shimizu W, Ling LH, Ng TP, Yap J, McMurray JJV, Zile MR, Richards AM, Anand IS, Lam CSP. Heart Failure With Preserved Ejection Fraction in the Young. Circulation. 2018 12 11; 138(24):2763-2773. PMID: 30565987.
      Citations: 43     Fields:    Translation:Humans
    62. Chandramouli C, Teng TK, Tay WT, Yap J, MacDonald MR, Tromp J, Yan L, Siswanto B, Reyes EB, Ngarmukos T, Yu CM, Hung CL, Anand I, Richards AM, Ling LH, Regensteiner JG, Lam CSP. Impact of diabetes and sex in heart failure with reduced ejection fraction patients from the ASIAN-HF registry. Eur J Heart Fail. 2019 03; 21(3):297-307. PMID: 30548089.
      Citations: 19     Fields:    Translation:Humans
    63. Sahl?n A, Ljungman P, Erlinge D, Chan MY, Yap J, Hausenloy DJ, Yeo KK, Jernberg T. Air pollution in relation to very short-term risk of ST-segment elevation myocardial infarction: Case-crossover analysis of SWEDEHEART. Int J Cardiol. 2019 Jan 15; 275:26-30. PMID: 30509372.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    64. Alpuche J, Qu?rino L, S?nchez-Vega JT, Yap J, P?rez-Campos E, Cabrera-Fuentes HA. The Role of Platelets in Ischemic Conditioning. Cond Med. 2018 Oct; 1(6):313-318. PMID: 30556056.
      Citations:    
    65. Arnold SV, Yap J, Lam CSP, Tang F, Tay WT, Teng THK, McGuire DK, Januzzi JL, Fonarow GC, Masoudi FA, Kosiborod M. Management of patients with diabetes and heart failure with reduced ejection fraction: An international comparison. Diabetes Obes Metab. 2019 02; 21(2):261-266. PMID: 30136348.
      Citations: 5     Fields:    Translation:Humans
    66. Teng TK, Tromp J, Tay WT, Anand I, Ouwerkerk W, Chopra V, Wander GS, Yap JJ, MacDonald MR, Xu CF, Chia YM, Shimizu W, Richards AM, Voors A, Lam CS. Prescribing patterns of evidence-based heart failure pharmacotherapy and outcomes in the ASIAN-HF registry: a cohort study. Lancet Glob Health. 2018 09; 6(9):e1008-e1018. PMID: 30103979.
      Citations: 80     Fields:    Translation:Humans
    67. Tromp J, Teng TH, Tay WT, Hung CL, Narasimhan C, Shimizu W, Park SW, Liew HB, Ngarmukos T, Reyes EB, Siswanto BB, Yu CM, Zhang S, Yap J, MacDonald M, Ling LH, Leineweber K, Richards AM, Zile MR, Anand IS, Lam CSP. Heart failure with preserved ejection fraction in Asia. Eur J Heart Fail. 2019 01; 21(1):23-36. PMID: 30113120.
      Citations: 69     Fields:    Translation:HumansPHPublic Health
    68. Chia YMF, Teng TK, Chandramouli C, Yap J, MacDonald M, Lam CSP. Clinical correlates and pharmacological management of Asian patients with concomitant diabetes mellitus and heart failure. Heart Fail Rev. 2018 05; 23(3):461-468. PMID: 29383639.
      Citations: 5     Fields:    Translation:Humans
    69. Zhang JM, Shuang D, Baskaran L, Wu W, Teo SK, Huang W, Gobeawan L, Allen JC, Tan RS, Su X, Ismail NB, Wan M, Su B, Zou H, Low R, Zhao X, Chi Y, Zhou J, Su Y, Lomarda AM, Chin CY, Fam JM, Keng FYJ, Wong ASL, Tan JWC, Yeo KK, Wong PEH, Chin CT, Ho KW, Yap J, Kassab GS, Chua T, Koh TH, Tan SY, Lim ST, Zhong L. Advanced analyses of computed tomography coronary angiography can help discriminate ischemic lesions. Int J Cardiol. 2018 Sep 15; 267:208-214. PMID: 29685695.
      Citations: 8     Fields:    Translation:Humans
    70. Lim FY, Yap J, Gao F, Teo LL, Lam CSP, Yeo KK. Correlation of the New York Heart Association classification and the cardiopulmonary exercise test: A systematic review. Int J Cardiol. 2018 07 15; 263:88-93. PMID: 29678511.
      Citations: 15     Fields:    Translation:Humans
    71. Goh VJ, Tromp J, Teng TK, Tay WT, Van Der Meer P, Ling LH, Siswanto BB, Hung CL, Shimizu W, Zhang S, Narasimhan C, Yu CM, Park SW, Ngarmukos T, Liew HB, Reyes E, Yap J, MacDonald M, Richards MA, Anand I, Lam CSP. Prevalence, clinical correlates, and outcomes of anaemia in multi-ethnic Asian patients with heart failure with reduced ejection fraction. ESC Heart Fail. 2018 08; 5(4):570-578. PMID: 29604185.
      Citations: 20     Fields:    Translation:Humans
    72. Tromp J, Tay WT, Ouwerkerk W, Teng TK, Yap J, MacDonald MR, Leineweber K, McMurray JJV, Zile MR, Anand IS, Richards AMR, Lam CSP. Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry. PLoS Med. 2018 03; 15(3):e1002541. PMID: 29584721.
      Citations: 88     Fields:    Translation:Humans
    73. Lim WK, Davila S, Teo JX, Yang C, Pua CJ, Bl?cker C, Lim JQ, Ching J, Yap JJL, Tan SY, Sahl?n A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK, Tan P. Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research. PLoS Biol. 2018 02; 16(2):e2004285. PMID: 29485983.
      Citations: 33     Fields:    Translation:Humans
    74. Yap J, Singh GD, Kim JS, Soni K, Chua K, Neo A, Koh CH, Armstrong EJ, Waldo SW, Shunk KA, Low RI, Hong MK, Jang Y, Yeo KK. Outcomes of primary percutaneous coronary intervention in acute myocardial infarction due to unprotected left main thrombosis: The Asia-Pacific Left Main ST-Elevation Registry (ASTER). J Interv Cardiol. 2018 Apr; 31(2):129-135. PMID: 29148142.
      Citations: 9     Fields:    Translation:Humans
    75. Chia YMF, Teng TK, Tan ESJ, Tay WT, Richards AM, Chin CWL, Shimizu W, Park SW, Hung CL, Ling LH, Ngarmukos T, Omar R, Siswanto BB, Narasimhan C, Reyes EB, Yu CM, Anand I, MacDonald MR, Yap J, Zhang S, Finkelstein EA, Lam CSP. Disparity Between Indications for and Utilization of Implantable Cardioverter Defibrillators in Asian Patients With Heart Failure. Circ Cardiovasc Qual Outcomes. 2017 Nov; 10(11). PMID: 29150533.
      Citations: 33     Fields:    Translation:HumansPHPublic Health
    76. McCurdy S, Liu CA, Yap J, Boisvert WA. Potential role of IL-37 in atherosclerosis. Cytokine. 2019 10; 122:154169. PMID: 28988706.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    77. Luo N, Teng TK, Tay WT, Anand IS, Kraus WE, Liew HB, Ling LH, O'Connor CM, Pi?a IL, Richards AM, Shimizu W, Whellan DJ, Yap J, Lam CSP, Mentz RJ. Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure. Am Heart J. 2017 Sep; 191:75-81. PMID: 28888273.
      Citations: 19     Fields:    Translation:Humans
    78. Shen T, Teo TY, Yap JJ, Yeo KK. Gender Differences in Knowledge, Attitudes and Practices towards Cardiovascular Disease and its Treatment among Asian Patients. Ann Acad Med Singap. 2017 Jan; 46(1):20-28. PMID: 28182814.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    79. Teo TY, Yap J, Shen T, Yeo KK. Complementary and alternative medicine use amongst patients with cardiovascular disease in Singapore. BMC Complement Altern Med. 2016 Nov 08; 16(1):446. PMID: 27825376.
      Citations: 7     Fields:    Translation:Humans
    80. Yap J, Earnest A, Lee V, Sng G, Lam C, Yeo KK. Impact of stock market volatility on mortality and cardiovascular events. Int J Cardiol. 2016 Nov 15; 223:318-319. PMID: 27543701.
      Citations: 3     Fields:    Translation:Humans
    81. Lam CS, Teng TK, Tay WT, Anand I, Zhang S, Shimizu W, Narasimhan C, Park SW, Yu CM, Ngarmukos T, Omar R, Reyes EB, Siswanto BB, Hung CL, Ling LH, Yap J, MacDonald M, Richards AM. Regional and ethnic differences among patients with heart failure in Asia: the Asian sudden cardiac death in heart failure registry. Eur Heart J. 2016 Nov 01; 37(41):3141-3153. PMID: 27502121.
      Citations: 85     Fields:    Translation:Humans
    82. Zhang JM, Zhong L, Luo T, Lomarda AM, Huo Y, Yap J, Lim ST, Tan RS, Wong AS, Tan JW, Yeo KK, Fam JM, Keng FY, Wan M, Su B, Zhao X, Allen JC, Kassab GS, Chua TS, Tan SY. Simplified Models of Non-Invasive Fractional Flow Reserve Based on CT Images. PLoS One. 2016; 11(5):e0153070. PMID: 27187726.
      Citations: 23     Fields:    Translation:Humans
    83. Yap J, Jin AZ, Nyunt SZ, Ng TP, Richards AM, Lam CS. Longitudinal Community-Based Study of QT Interval and Mortality in Southeast Asians. PLoS One. 2016; 11(5):e0154901. PMID: 27148971.
      Citations: 3     Fields:    Translation:Humans
    84. Santhanakrishnan R, Wang N, Larson MG, Magnani JW, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 03 25; 5(3):e002956. PMID: 27016575.
      Citations: 21     Fields:    Translation:Humans
    85. Tan ES, Yap J, Xu CF, Feng L, Nyunt SZ, Santhanakrishnan R, Chan MM, Seow SC, Ching CK, Yeo KK, Richards AM, Ng TP, Lim TW, Lam CS. Association of Age, Sex, Body Size and Ethnicity with Electrocardiographic Values in Community-based Older Asian Adults. Heart Lung Circ. 2016 Jul; 25(7):705-11. PMID: 26935158.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    86. Tay E, Muda N, Yap J, Muller DW, Santoso T, Walters DL, Liu X, Yamen E, Jansz P, Yip J, Zambahari R, Passage J, Ding ZP, Wang J, Scalia G, Soesanto AM, Yeo KK. The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation. Catheter Cardiovasc Interv. 2016 Jun; 87(7):E275-81. PMID: 26508564.
      Citations: 12     Fields:    Translation:Humans
    87. Yap J, Lim FY, Gao F, Teo LL, Lam CS, Yeo KK. Correlation of the New York Heart Association Classification and the 6-Minute Walk Distance: A Systematic Review. Clin Cardiol. 2015 Oct; 38(10):621-8. PMID: 26442458.
      Citations: 47     Fields:    Translation:Humans
    88. Yap J, Tan JL, Le TT, Gao F, Zhong L, Liew R, Tan SY, Tan RS. Assessment of left ventricular preload by cardiac magnetic resonance imaging predicts exercise capacity in adult operated tetralogy of Fallot: a retrospective study. BMC Cardiovasc Disord. 2014 Sep 23; 14:122. PMID: 25245139.
      Citations: 6     Fields:    Translation:Humans
    89. Lee VJ, Chen MI, Yap J, Ong J, Lim WY, Lin RT, Barr I, Ong JB, Mak TM, Goh LG, Leo YS, Kelly PM, Cook AR. Comparability of different methods for estimating influenza infection rates over a single epidemic wave. Am J Epidemiol. 2011 Aug 15; 174(4):468-78. PMID: 21719743.
      Citations: 28     Fields:    Translation:HumansCellsPHPublic Health
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