Intermediate Filaments

"Intermediate Filaments" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cytoplasmic filaments intermediate in diameter (about 10 nanometers) between the microfilaments and the microtubules. They may be composed of any of a number of different proteins and form a ring around the cell nucleus.

Descriptor ID	D007382
MeSH Number(s)	A11.284.430.214.190.750.410
Concept/Terms	Intermediate Filaments Intermediate Filaments Filament, Intermediate Filaments, Intermediate Intermediate Filament Neurofilaments Neurofilaments Neurofilament Tonofilaments Tonofilaments Tonofilament

Below are MeSH descriptors whose meaning is more general than "Intermediate Filaments".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Intracellular Space [A11.284.430]
Cytoplasm [A11.284.430.214]
Cytoplasmic Structures [A11.284.430.214.190]
Cytoskeleton [A11.284.430.214.190.750]
Intermediate Filaments [A11.284.430.214.190.750.410]

Below are MeSH descriptors whose meaning is related to "Intermediate Filaments".

Below are MeSH descriptors whose meaning is more specific than "Intermediate Filaments".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Intermediate Filaments" by people in this website by year, and whether "Intermediate Filaments" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2016 and 2017 and 2019 and 2022 and 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	1	0	1
2017	1	0	1
2019	0	1	1
2022	0	1	1
2025	0	1	1

Below are the most recent publications written about "Intermediate Filaments" by people in Profiles.

Hou C, Yu F, Cao C, Wang T, Pan Z, Zhong M, Liu X, Yao X, Zhang K, Yang Z, Guo J. Aurora B maintains spherical shape of mitotic cells via simultaneously stabilizing myosin II and vimentin. J Mol Cell Biol. 2025 Dec 29; 17(5).

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Yang Z, Arja RD, Zhu T, Sarkis GA, Patterson RL, Romo P, Rathore DS, Moghieb A, Abbatiello S, Robertson CS, Haskins WE, Kobeissy F, Wang KKW. Characterization of Calpain and Caspase-6-Generated Glial Fibrillary Acidic Protein Breakdown Products Following Traumatic Brain Injury and Astroglial Cell Injury. Int J Mol Sci. 2022 Aug 11; 23(16).

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Zueva L, Golubeva T, Korneeva E, Resto O, Inyushin M, Khmelinskii I, Makarov V. Quantum mechanism of light energy propagation through an avian retina. J Photochem Photobiol B. 2019 Aug; 197:111543.

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Khmelinskii I, Golubeva T, Korneeva E, Inyushin M, Zueva L, Makarov V. Spectral selectivity model for light transmission by the intermediate filaments in M?ller cells. J Photochem Photobiol B. 2017 Aug; 173:282-290.

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Zueva L, Golubeva T, Korneeva E, Makarov V, Khmelinskii I, Inyushin M. Foveolar M?ller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency. Microsc Microanal. 2016 Apr; 22(2):379-86.

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Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7552-6.

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Gheuens J, Cras P, Perry G, Boons J, Ceuterick-de Groote C, L?bke U, Mercken M, Tabaton M, Gambetti PL, Vandermeeren M, et al. Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases. Brain Res. 1991 Aug 30; 558(1):43-52.

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Perry G, Kawai M, Tabaton M, Onorato M, Mulvihill P, Richey P, Morandi A, Connolly JA, Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J Neurosci. 1991 Jun; 11(6):1748-55.

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Kawahara H, Cadrin M, Perry G, Autilio-Gambetti L, Swierenga SH, Metuzals J, Marceau N, French SW. Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion. Hepatology. 1990 Mar; 11(3):435-48.

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Kasper M, Terpe HJ, Perry G. Age-dependent pattern of intermediate filament protein expression in the human pineal gland. J Hirnforsch. 1990; 31(2):215-21.

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