Insulin Resistance

"Insulin Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Descriptor ID	D007333
MeSH Number(s)	C18.452.394.968.500 G07.690.773.984.617
Concept/Terms	Insulin Resistance Insulin Resistance Resistance, Insulin Insulin Sensitivity Insulin Sensitivity Sensitivity, Insulin

Below are MeSH descriptors whose meaning is more general than "Insulin Resistance".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Hyperinsulinism [C18.452.394.968]
Insulin Resistance [C18.452.394.968.500]
Biological Sciences [G]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Drug Resistance [G07.690.773.984]
Insulin Resistance [G07.690.773.984.617]

Below are MeSH descriptors whose meaning is related to "Insulin Resistance".

Below are MeSH descriptors whose meaning is more specific than "Insulin Resistance".

Insulin Resistance
Metabolic Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin Resistance" by people in this website by year, and whether "Insulin Resistance" was a major or minor topic of these publications.

Bar chart showing 141 publications over 23 distinct years, with a maximum of 11 publications in 2013 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	2	2	4
2005	3	0	3
2006	6	2	8
2007	3	3	6
2008	1	2	3
2009	2	2	4
2010	2	0	2
2011	6	3	9
2012	1	5	6
2013	4	7	11
2014	3	3	6
2015	4	4	8
2016	4	4	8
2017	6	4	10
2018	5	2	7
2019	5	5	10
2020	6	1	7
2021	4	3	7
2022	3	0	3
2023	5	0	5
2024	8	3	11
2025	2	0	2

Below are the most recent publications written about "Insulin Resistance" by people in Profiles.

Madlala HP, Jao J, Roussos G, Mendham AE, Myer L, Abrams E, Geffen H, Mukonda E, Modibedi R, Odayar J, Matyesini S, Dugas LR, Goedecke JH, Catalano P, McComsey GA, Gerschenson M. Gluteal Adipose Tissue Mitochondrial Respiration and Insulin Sensitivity in Pregnant South African Women Living With HIV on Tenofovir-Lamivudine-Dolutegravir. J Acquir Immune Defic Syndr. 2025 Dec 15; 100(5):462-470.

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Karadeniz Y, Caliskan Burgucu H, Ozturk Y, Yarar Z, Kaynak H, Can M, Karakose M. Comparison of triglyceride-glucose index and HOMA-IR in assessing insulin resistance in acromegaly: a case-control study. Endokrynol Pol. 2025; 76(4):442-449.

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Wang Z, Veerareddy V, Tang X, Thompson KJ, Krishnan S, Kalari KR, Kandimalla KK. QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid-Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium. CPT Pharmacometrics Syst Pharmacol. 2025 Mar; 14(3):561-571.

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Debarba LK, Jayarathne HSM, Stilgenbauer L, Dos Santos ALT, Koshko L, Scofield S, Sullivan R, Mandal A, Klueh U, Sadagurski M. Microglia Mediate Metabolic Dysfunction From Common Air Pollutants Through NF-?B Signaling. Diabetes. 2024 Dec 01; 73(12):2065-2077.

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Jao J, Bonner LB, Dobinda K, Powis KM, Sun S, Legbedze J, Mmasa KN, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Abrams EJ, Kurland IJ, Geffner ME. Lower Insulin Sensitivity Through 36 Months of Life With in Utero HIV and Antiretroviral Exposure in Botswana: Results From the Tshilo Dikotla Study. Clin Infect Dis. 2024 09 26; 79(3):727-733.

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Abrams EJ, Jao J, Madlala HP, Zerbe A, Catalano P, Gerschenson M, Goedecke JH, Gomba Y, Josefson J, Kurland IJ, Legbedze J, McComsey GA, Matyesini S, Mukonda E, Robinson D, Myer L. An observational cohort study to investigate the impact of dolutegravir in pregnancy and its obesogenic effects on the metabolic health of women living with HIV and their children: Study protocol. PLoS One. 2024; 19(8):e0307296.

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Ishihara T, Kato K, Matsumoto K, Tanaka M, Hara A, Shiraki Y, Morisaki H, Urano Y, Ando R, Ito K, Mii S, Esaki N, Furuhashi K, Takefuji M, Suganami T, Murohara T, Enomoto A. Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis. Genes Cells. 2024 Oct; 29(10):902-920.

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Ganguly A, Ghosh S, Jin P, Wadehra M, Devaskar SU. Omega-3 reverses the metabolic and epigenetically regulated placental phenotype acquired from preconceptional and peri-conceptional exposure to air pollutants. J Nutr Biochem. 2024 12; 134:109735.

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Gojanovich GS, Yu W, Zhang ZJ, Jacobson DL, Yao TJ, Jao J, Libutti DE, Geffner ME, Gerschenson M. Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S. Mitochondrion. 2024 Sep; 78:101936.

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Hajri T, Gharib M, Fungwe T, M'Koma A. Very low-density lipoprotein receptor mediates triglyceride-rich lipoprotein-induced oxidative stress and insulin resistance. Am J Physiol Heart Circ Physiol. 2024 10 01; 327(4):H733-H748.

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