Glutathione Peroxidase

"Glutathione Peroxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water. EC 1.11.1.9.

Descriptor ID	D005979
MeSH Number(s)	D08.811.682.732.500
Concept/Terms	Glutathione Peroxidase Glutathione Peroxidase Peroxidase, Glutathione Selenoglutathione Peroxidase Selenoglutathione Peroxidase Peroxidase, Selenoglutathione Glutathione Lipoperoxidase Glutathione Lipoperoxidase Lipoperoxidase, Glutathione

Below are MeSH descriptors whose meaning is more general than "Glutathione Peroxidase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Peroxidases [D08.811.682.732]
Glutathione Peroxidase [D08.811.682.732.500]

Below are MeSH descriptors whose meaning is related to "Glutathione Peroxidase".

Below are MeSH descriptors whose meaning is more specific than "Glutathione Peroxidase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glutathione Peroxidase" by people in this website by year, and whether "Glutathione Peroxidase" was a major or minor topic of these publications.

Bar chart showing 52 publications over 23 distinct years, with a maximum of 6 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	0	1	1
2001	2	3	5
2003	0	1	1
2004	0	2	2
2005	0	4	4
2006	0	3	3
2007	1	1	2
2008	1	2	3
2009	0	1	1
2010	1	5	6
2011	0	3	3
2012	0	3	3
2013	1	0	1
2014	0	2	2
2016	0	1	1
2017	0	1	1
2018	1	3	4
2019	0	2	2
2020	1	1	2
2021	0	1	1
2022	1	1	2
2024	1	0	1

Below are the most recent publications written about "Glutathione Peroxidase" by people in Profiles.

Shimada BK, Ogawa-Wong AN, Soares AG, Hallam KA, Santiago PJD, Saelua K, Nakahara-Akita KK, Torres DJ, Brockman JD, Kurokawa S, Ewell KL, Bellinger MT, Toh P, Lagatta Pamplona Remedios G, Alfulaij N, Swanson SM, Seyedali A, Zavacki AM, Berry MJ, Seale LA. Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes. Am J Physiol Endocrinol Metab. 2026 02 01; 330(2):E000.

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Santiago PJD, Shimada BK, Alfulaij N, Hallam KA, Soares AG, Young V, Swanson SM, Remedios GL, Toh P, Seale LA. Targeted Disruption of Selenocysteine Lyase in Brown Adipocytes Controls Glutathione Peroxidase 1 and 4 Expression in Males. Biol Trace Elem Res. 2026 May; 204(5):3437-3450.

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Shimada BK, Watanabe M, Apo Takayama NK, Soares AG, Hallam KA, Rivers OS, Ewell K, Santiago PJD, Swanson SM, Toh P, Alfulaij N, Berry MJ, Seale LA. Cardiac redox imbalance upon disruption of selenocysteine decomposition in mice. Am J Physiol Heart Circ Physiol. 2025 Dec 01; 329(6):H1480-H1496.

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Yang H, Wang Z, Li L, Wang X, Wei X, Gou S, Ding Z, Cai Z, Ling Q, Hoffmann PR, He J, Liu F, Huang Z. Mannose coated selenium nanoparticles normalize intestinal homeostasis in mice and mitigate colitis by inhibiting NF-?B activation and enhancing glutathione peroxidase expression. J Nanobiotechnology. 2024 Oct 10; 22(1):613.

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Baba K, Suen TC, Goyal V, Stowie A, Davidson A, DeBruyne J, Tosini G. The circadian clock mediates the response to oxidative stress in a cone photoreceptor?like (661W) cell line via regulation of glutathione peroxidase activity. F1000Res. 2022; 11:1072.

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Nicholson JL, Toh P, Alfulaij N, Berry MJ, Torres DJ. New insights on selenoproteins and neuronal function. Free Radic Biol Med. 2022 09; 190:55-61.

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Watanabe LM, Hashimoto AC, Torres DJ, Alfulaij N, Peres R, Sultana R, Maunakea AK, Berry MJ, Seale LA. Effect of statin treatment in obese selenium-supplemented mice lacking selenocysteine lyase. Mol Cell Endocrinol. 2021 08 01; 533:111335.

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Seale LA, Torres DJ, Berry MJ, Pitts MW. A role for selenium-dependent GPX1 in SARS-CoV-2 virulence. Am J Clin Nutr. 2020 08 01; 112(2):447-448.

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Watanabe LM, Hashimoto AC, Torres DJ, Berry MJ, Seale LA. Effects of selenium supplementation on diet-induced obesity in mice with a disruption of the selenocysteine lyase gene. J Trace Elem Med Biol. 2020 Dec; 62:126596.

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Goodla L, Manubolu M, Pathakoti K, Jayakumar T, Sheu JR, Fraker M, Tchounwou PB, Poondamalli PR. Protective Effects of Ammannia baccifera Against CCl4-Induced Oxidative Stress in Rats. Int J Environ Res Public Health. 2019 04 23; 16(8).

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