"Drug Antagonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
| Descriptor ID |
D004336
|
| MeSH Number(s) |
G07.690.773.968.310
|
| Concept/Terms |
Drug Antagonism- Drug Antagonism
- Antagonism, Drug
- Antagonisms, Drug
- Drug Antagonisms
|
Below are MeSH descriptors whose meaning is more general than "Drug Antagonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Antagonism".
This graph shows the total number of publications written about "Drug Antagonism" by people in this website by year, and whether "Drug Antagonism" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Drug Antagonism" by people in Profiles.
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Carneiro AB, Iaciura BM, Nohara LL, Lopes CD, Veas EM, Mariano VS, Bozza PT, Lopes UG, Atella GC, Almeida IC, Silva-Neto MA. Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-?B translocation and MAPK/ERK phosphorylation. PLoS One. 2013; 8(9):e76233.
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Aliev G, Obrenovich ME, Seyidova D, Rzayev NM, Aliyev AS, Raina AK, Lamanna JC, Smith MA, Perry G. X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment. J Submicrosc Cytol Pathol. 2003 Jul; 35(3):253-66.
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De Soto JA, Bowen D, Davis JH, Southerland WM, Hawkins M. Sequence- and time-dependent antagonism between raloxifene and methotrexate in human breast cancer cells. Anticancer Res. 2002 Mar-Apr; 22(2A):1007-9.
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Wayner MJ, Armstrong DL, Phelix CF. Nicotine blocks angiotensin II inhibition of LTP in the dentate gyrus. Peptides. 1996; 17(7):1127-33.