"Apomorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.
| Descriptor ID |
D001058
|
| MeSH Number(s) |
D03.132.098.038.290 D03.633.100.531.085.030.290 D03.633.400.095.290
|
| Concept/Terms |
Apomorphine Hydrochloride, Anhydrous- Apomorphine Hydrochloride, Anhydrous
- Anhydrous Apomorphine Hydrochloride
- Hydrochloride, Anhydrous Apomorphine
- Apomorphine Hydrochloride Anhydrous
- Anhydrous, Apomorphine Hydrochloride
- Hydrochloride Anhydrous, Apomorphine
Apomorphine Hydrochloride- Apomorphine Hydrochloride
- Hydrochloride, Apomorphine
- Apomorphine Hydrochloride, Hemihydrate
- Hemihydrate Apomorphine Hydrochloride
- Hydrochloride, Hemihydrate Apomorphine
|
Below are MeSH descriptors whose meaning is more general than "Apomorphine".
Below are MeSH descriptors whose meaning is more specific than "Apomorphine".
This graph shows the total number of publications written about "Apomorphine" by people in this website by year, and whether "Apomorphine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Apomorphine" by people in Profiles.
-
Onyameh EK, Bricker BA, Eyunni SVK, Voshavar C, Gonela UM, Ofori E, Jenkins A, Ablordeppey SY. A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice? Bioorg Med Chem. 2021 01 15; 30:115943.
-
Sampson D, Bricker B, Zhu XY, Peprah K, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Further evaluation of the tropane analogs of haloperidol. Bioorg Med Chem Lett. 2014 Sep 01; 24(17):4294-7.
-
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, Khan A, Roth BL. Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one. Bioorg Med Chem. 2008 Aug 01; 16(15):7291-301.
-
Sikazwe DM, Li S, Lyles-Eggleston M, Ablordeppey SY. The acute EPS of haloperidol may be unrelated to its metabolic transformation to BCPP+. Bioorg Med Chem Lett. 2003 Nov 03; 13(21):3779-82.
-
Lutfy K, Do T, Maidment NT. Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. Psychopharmacology (Berl). 2001 Feb; 154(1):1-7.
-
Merchant KM, Gill GS, Harris DW, Huff RM, Eaton MJ, Lookingland K, Lutzke BS, Mccall RB, Piercey MF, Schreur PJ, Sethy VH, Smith MW, Svensson KA, Tang AH, Vonvoigtlander PF, Tenbrink RE. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J Pharmacol Exp Ther. 1996 Dec; 279(3):1392-403.
-
al-Zadjali KH, Imler MP, Ohia SE. Inhibitory effect of prostaglandins on dopamine release from the retina. Gen Pharmacol. 1994 Mar; 25(2):289-96.
-
Eaton MJ, Gopalan C, Kim E, Lookingland KJ, Moore KE. Comparison of the effects of the dopamine D2 agonist quinelorane on tuberoinfundibular dopaminergic neuronal activity in male and female rats. Brain Res. 1993 Nov 26; 629(1):53-8.
-
Oriaku ET, Soliman KF. Brain cholinergic involvement in the diurnal variations of the rapid development of tolerance to the hypothermic effect of apomorphine. Pharmacology. 1988; 37(1):8-15.
-
Khorram O, Depalatis LR, McCann SM. Hypothalamic control of prolactin secretion during the perinatal period in the rat. Endocrinology. 1984 Nov; 115(5):1698-704.