Antigen-Presenting Cells

"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.

Descriptor ID	D000938
MeSH Number(s)	A11.066 A15.382.066
Concept/Terms	Antigen-Presenting Cells Antigen-Presenting Cells Antigen Presenting Cells Antigen-Presenting Cell Cell, Antigen-Presenting Cells, Antigen-Presenting Accessory Cells, Immunologic Immunologic Accessory Cells Cells, Immunologic Accessory Immunologic Accessory Cell Accessory Cell, Immunologic Cell, Immunologic Accessory

Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".

Anatomy [A]
Cells [A11]
Antigen-Presenting Cells [A11.066]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Antigen-Presenting Cells [A15.382.066]

Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.

Bar chart showing 23 publications over 13 distinct years, with a maximum of 3 publications in 2003 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	1	2
2001	0	1	1
2002	0	1	1
2003	1	2	3
2004	0	2	2
2005	1	1	2
2006	0	2	2
2009	1	0	1
2011	1	0	1
2012	0	2	2
2013	2	1	3
2014	2	0	2
2015	0	1	1

Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.

Sharma P, Levy O, Dowling DJ. The TLR5 Agonist Flagellin Shapes Phenotypical and Functional Activation of Lung Mucosal Antigen Presenting Cells in Neonatal Mice. Front Immunol. 2020; 11:171.

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Lindsay KE, Bhosle SM, Zurla C, Beyersdorf J, Rogers KA, Vanover D, Xiao P, Ara?nga M, Shirreff LM, Pitard B, Baumhof P, Villinger F, Santangelo PJ. Visualization of early events in mRNA vaccine delivery in non-human primates via PET-CT and near-infrared imaging. Nat Biomed Eng. 2019 05; 3(5):371-380.

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Sosa RA, Murphey C, Robinson RR, Forsthuber TG. IFN-? ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation. Proc Natl Acad Sci U S A. 2015 Sep 08; 112(36):E5038-47.

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Li XL, Sluijter M, Doorduijn EM, Kale SP, McFerrin H, Liu YY, Li Y, Mottamal M, Yao X, Du F, Gu B, Hoang K, Nguyen YH, Taylor N, Stephens CR, van Hall T, Zhang QJ. Limited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phase. PLoS One. 2014; 9(11):e108192.

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Sharma G, Holt RA. T-cell epitope discovery technologies. Hum Immunol. 2014 Jun; 75(6):514-9.

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Chittasupho C, Sestak J, Shannon L, Siahaan TJ, Vines CM, Berkland C. Hyaluronic acid graft polymers displaying peptide antigen modulate dendritic cell response in vitro. Mol Pharm. 2014 Jan 06; 11(1):367-73.

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Bridenbaugh EA, Wang W, Srimushnam M, Cromer WE, Zawieja SD, Schmidt SE, Jupiter DC, Huang HC, Van Buren V, Zawieja DC. An immunological fingerprint differentiates muscular lymphatics from arteries and veins. Lymphat Res Biol. 2013 Sep; 11(3):155-71.

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Spencer CT, Dragovic SM, Conant SB, Gray JJ, Zheng M, Samir P, Niu X, Moutaftsi M, Van Kaer L, Sette A, Link AJ, Joyce S. Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses. Eur J Immunol. 2013 May; 43(5):1162-72.

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Hung CY, Hurtgen BJ, Bellecourt M, Sanderson SD, Morgan EL, Cole GT. An agonist of human complement fragment C5a enhances vaccine immunity against Coccidioides infection. Vaccine. 2012 Jun 29; 30(31):4681-90.

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Woodrow KA, Bennett KM, Lo DD. Mucosal vaccine design and delivery. Annu Rev Biomed Eng. 2012; 14:17-46.

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