Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.

Yu M, Ye H, De-Paula RB, Mangleburg CG, Wu T, Lee TV, Li Y, Duong D, Phillips B, Cruchaga C, Allen GI, Seyfried NT, Al-Ramahi I, Botas J, Shulman JM. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genet. 2023 05; 19(5):e1010760.

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subject areas

Aging
alpha-Synuclein
Animals
Animals, Genetically Modified
Drosophila
Glucosylceramidase
Humans
Lysosomes
Parkinson Disease
Transferases (Other Substituted Phosphate Groups)

authors with profiles

Joshua M. Shulman

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