Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients.

McCarthy MJ, Wei H, Landgraf D, Le Roux MJ, Welsh DK. Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients. Eur Neuropsychopharmacol. 2016 08; 26(8):1310-9.

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subject areas

Animals
Antimanic Agents
Bipolar Disorder
Cells, Cultured
Circadian Rhythm
Cyclic AMP Response Element-Binding Protein
Dual Specificity Phosphatase 6
Early Growth Response Protein 1
ets-Domain Protein Elk-1
Genes, Reporter
Humans
Lithium
MAP Kinase Signaling System
Mice
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
NIH 3T3 Cells
Period Circadian Proteins
Phosphorylation
Protein Kinase Inhibitors
Protein Processing, Post-Translational
RNA Interference

authors with profiles

Michael McCarthy

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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