Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters.

Kroczynska B, Cutrone R, Bocchetta M, Yang H, Elmishad AG, Vacek P, Ramos-Nino M, Mossman BT, Pass HI, Carbone M. Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14128-33.

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subject areas

Animals
Asbestos, Crocidolite
Carcinogens
Cells, Cultured
Cricetinae
Enzyme Activation
Epithelial Cells
Epithelium
Female
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Humans
Matrix Metalloproteinase 1
Matrix Metalloproteinase 9
Mesocricetus
Mesothelioma
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Proto-Oncogene Proteins c-fos
Repressor Proteins
RNA, Small Interfering
Simian virus 40
Transcription Factor AP-1
Transcriptional Activation

authors with profiles

Michele Carbone, MD, PhD.

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