Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide.

Villamil A, Chrysant SG, Calhoun D, Schober B, Hsu H, Matrisciano-Dimichino L, Zhang J. Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. J Hypertens. 2007 Jan; 25(1):217-26.

View in: PubMed

subject areas

Amides
Antihypertensive Agents
Blood Pressure
Dose-Response Relationship, Drug
Double-Blind Method
Drug Synergism
Drug Therapy, Combination
Female
Fumarates
Humans
Hydrochlorothiazide
Hypertension
Least-Squares Analysis
Male
Middle Aged
Renin
Time Factors
Treatment Outcome

authors with profiles

David Calhoun

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support