TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation.

Lau AW, Pringle LM, Quick L, Riquelme DN, Ye Y, Oliveira AM, Chou MM. TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation. J Biol Chem. 2010 Nov 19; 285(47):37111-20.

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subject areas

ADP-Ribosylation Factors
Alkaline Phosphatase
Animals
Autocrine Communication
Blotting, Western
Bone Cysts, Aneurysmal
Bone Morphogenetic Proteins
Cell Differentiation
Cell Proliferation
Cell Transformation, Neoplastic
Culture Media, Conditioned
Electrophoretic Mobility Shift Assay
Endopeptidases
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Hela Cells
Humans
Mice
Mutagenesis, Site-Directed
Oligonucleotide Array Sequence Analysis
Oncogenes
Osteoblasts
Protein Transport
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Signal Transduction
Ubiquitin Thiolesterase

authors with profiles

Alan F. Lau, PhD

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