LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1.

Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012 May 01; 21(9):1931-44.

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subject areas

Amino Acid Substitution
Animals
Cell Line
Dynamins
GTP Phosphohydrolases
Humans
Microscopy, Electron, Transmission
Microtubule-Associated Proteins
Mitochondria
Mitochondrial Proteins
Mutant Proteins
Mutation, Missense
Neurons
Parkinson Disease
Rats
Recombinant Proteins
Stress, Physiological
Transfection

authors with profiles

George Perry

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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