A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice?

Onyameh EK, Bricker BA, Eyunni SVK, Voshavar C, Gonela UM, Ofori E, Jenkins A, Ablordeppey SY. A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice? Bioorg Med Chem. 2021 01 15; 30:115943.

View in: PubMed

subject areas

Animals
Antipsychotic Agents
Apomorphine
Behavior, Animal
Dose-Response Relationship, Drug
Male
Mice
Molecular Structure
Piperazines
Pyridines
Receptors, Dopamine D2
Structure-Activity Relationship

authors with profiles

Seth Y. Ablordeppey
Suresh Eyunni

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support