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Pedro Ferchmin

TitleCoordinator, Neuronal Glia Facility
Faculty RankProfessor
InstitutionUniversidad Central Del Caribe
DepartmentDepartment of Biochemistry
AddressUniversidad Central del Caribe
Call Box 60-237
Bayamon PR 00960
Phone787-798-3001 X2033
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    Collapse Biography 
    Collapse awards and honors
    1965 - 1967Fellow of the National University of Cordoba , National University of Buenos Aires
    1965Premio Universidad (University Honor Award), National University of Cordoba, Argentina
    1967 - 1968Research Fellow of the National Council for Science and Technology
    1993Scholarly Productivity Award (EPSCOR, NSF)

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hu J, Ferchmin PA, Hemmerle AM, Seroogy KB, Eterovic VA, Hao J. 4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease. Front Neurosci. 2017; 11:272. PMID: 28611572.
    2. Ferchmin PA, Pérez D, Cuadrado BL, Carrasco M, Martins AH, Eterovic VA. Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices. Neurochem Res. 2015 Oct; 40(10):2143-51. PMID: 26438150.
      Citations:    Fields:    Translation:AnimalsCells
    3. Ferchmin PA, Eterovic VA. Preface for the Special Issue Prof. Lynn Wecker. Neurochem Res. 2015 Oct; 40(10):2007-8. PMID: 26526302.
      Citations:    Fields:    Translation:Humans
    4. Vélez-Carrasco W, Green CE, Catz P, Furimsky A, O'Loughlin K, Eterovic VA, Ferchmin PA. Pharmacokinetics and Metabolism of 4R-Cembranoid. PLoS One. 2015; 10(3):e0121540. PMID: 25811857.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    5. Berríos VO, Boukli NM, Rodriguez JW, Negraes PD, Schwindt TT, Trujillo CA, Oliveira SL, Cubano LA, Ferchmin PA, Eterovic VA, Ulrich H, Martins AH. Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation. Neurochem Res. 2015 Oct; 40(10):2091-101. PMID: 25758980.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Martins AH, Hu J, Xu Z, Mu C, Alvarez P, Ford BD, El Sayed K, Eterovic VA, Ferchmin PA, Hao J. Neuroprotective activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) in vitro and in vivo in rodent models of brain ischemia. Neuroscience. 2015 Apr 16; 291:250-259. PMID: 25677097.
      Citations: 9     Fields:    Translation:AnimalsCells
    7. Ferchmin PA, Andino M, Reyes Salaman R, Alves J, Velez-Roman J, Cuadrado B, Carrasco M, Torres-Rivera W, Segarra A, Martins AH, Lee JE, Eterovic VA. 4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration. Neurotoxicology. 2014 Sep; 44:80-90. PMID: 24928201.
      Citations: 17     Fields:    Translation:Animals
    8. Torres-Rivera W, Pérez D, Park KY, Carrasco M, Platt MO, Eterovic VA, Ferchmin PA, Ulrich H, Martins AH. Kinin-B2 receptor exerted neuroprotection after diisopropylfluorophosphate-induced neuronal damage. Neuroscience. 2013 Sep 05; 247:273-9. PMID: 23735753.
      Citations: 5     Fields:    Translation:AnimalsCells
    9. Eterovic VA, Del Valle-Rodriguez A, Pérez D, Carrasco M, Khanfar MA, El Sayed KA, Ferchmin PA. Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: preliminary structure-activity relationship and pharmacophore modeling. Bioorg Med Chem. 2013 Aug 01; 21(15):4678-86. PMID: 23769165.
      Citations: 5     Fields:    Translation:Animals
    10. Ferchmin PA, Pérez D, Castro Alvarez W, Penzo MA, Maldonado HM, Eterovic VA. ?-Aminobutyric acid type A receptor inhibition triggers a nicotinic neuroprotective mechanism. J Neurosci Res. 2013 Mar; 91(3):416-25. PMID: 23280428.
      Citations: 5     Fields:    Translation:HumansAnimals
    11. Rodriguez-Mercado R, Ford GD, Xu Z, Kraiselburd EN, Martinez MI, Eterovic VA, Colon E, Rodriguez IV, Portilla P, Ferchmin PA, Gierbolini L, Rodriguez-Carrasquillo M, Powell MD, Pulliam JV, McCraw CO, Gates A, Ford BD. Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke. Comp Med. 2012 Oct; 62(5):427-38. PMID: 23114047.
      Citations: 10     Fields:    Translation:AnimalsCells
    12. Martins AH, Alves JM, Perez D, Carrasco M, Torres-Rivera W, Eterovic VA, Ferchmin PA, Ulrich H. Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists. PLoS One. 2012; 7(2):e30755. PMID: 22348022.
      Citations: 15     Fields:    Translation:Animals
    13. Eterovic VA, Pérez D, Martins AH, Cuadrado BL, Carrasco M, Ferchmin PA. A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity. Toxicol In Vitro. 2011 Oct; 25(7):1468-74. PMID: 21569834.
      Citations: 7     Fields:    Translation:Animals
    14. Ferchmin PA, Pagán OR, Ulrich H, Szeto AC, Hann RM, Eterovic VA. Actions of octocoral and tobacco cembranoids on nicotinic receptors. Toxicon. 2009 Dec 15; 54(8):1174-82. PMID: 19281835.
      Citations: 13     Fields:    Translation:Animals
    15. Ghiani CA, Beltran-Parrazal L, Sforza DM, Malvar JS, Seksenyan A, Cole R, Smith DJ, Charles A, Ferchmin PA, de Vellis J. Genetic program of neuronal differentiation and growth induced by specific activation of NMDA receptors. Neurochem Res. 2007 Feb; 32(2):363-76. PMID: 17191130.
      Citations: 7     Fields:    Translation:AnimalsCells
    16. Ghiani CA, Lelievre V, Beltran-Parrazal L, Sforza DM, Malvar J, Smith DJ, Charles AC, Ferchmin PA, de Vellis J. Gene expression is differentially regulated by neurotransmitters in embryonic neuronal cortical culture. J Neurochem. 2006 Apr; 97 Suppl 1:35-43. PMID: 16635248.
      Citations: 5     Fields:    Translation:AnimalsCells
    17. Ferchmin PA, Hao J, Perez D, Penzo M, Maldonado HM, Gonzalez MT, Rodriguez AD, de Vellis J. Tobacco cembranoids protect the function of acute hippocampal slices against NMDA by a mechanism mediated by alpha4beta2 nicotinic receptors. J Neurosci Res. 2005 Dec 01; 82(5):631-41. PMID: 16247800.
      Citations: 17     Fields:    Translation:AnimalsCells
    18. Ferchmin PA, Perez D, Eterovic VA, de Vellis J. Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices. J Pharmacol Exp Ther. 2003 Jun; 305(3):1071-8. PMID: 12649299.
      Citations: 15     Fields:    Translation:Animals
    19. Ferchmin PA, Lukas RJ, Hann RM, Fryer JD, Eaton JB, Pagán OR, Rodríguez AD, Nicolau Y, Rosado M, Cortés S, Eterovic VA. Tobacco cembranoids block behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptor function. J Neurosci Res. 2001 Apr 01; 64(1):18-25. PMID: 11276047.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Ferchmin PA, Pérez D, Biello M. Spermine is neuroprotective against anoxia and N-methyl-D-aspartate in hippocampal slices. Brain Res. 2000 Mar 24; 859(2):273-9. PMID: 10719074.
      Citations: 14     Fields:    Translation:Animals
    21. Claudio OI, Ferchmin P, Velísek L, Sperber EF, Moshé SL, Ortiz JG. Plasticity of excitatory amino acid transporters in experimental epilepsy. Epilepsia. 2000; 41 Suppl 6:S104-10. PMID: 10999530.
      Citations:    Fields:    Translation:AnimalsCells
    22. Eterovic VA, Lu R, Eakin AE, Rodríguez AD, Ferchmin PA. Determinants of phencyclidine potency on the nicotinic acetylcholine receptors from muscle and electric organ. Cell Mol Neurobiol. 1999 Dec; 19(6):745-57. PMID: 10456235.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Hann RM, Pagán OR, Gregory L, Jácome T, Rodríguez AD, Ferchmin PA, Lu R, Eterovic VA. Characterization of cembranoid interaction with the nicotinic acetylcholine receptor. J Pharmacol Exp Ther. 1998 Oct; 287(1):253-60. PMID: 9765345.
      Citations: 9     Fields:    Translation:AnimalsCells
    24. Eterovic VA, Torres E, Ferchmin PA. Spermine does not compete with omega-conotoxin GVIA in the striatum radiatum of the hippocampal slice. Brain Res. 1997 Oct 24; 772(1-2):191-202. PMID: 9406972.
      Citations: 1     Fields:    Translation:Animals
    25. Ferchmin PA, Eterovic VA, Rivera EM, Teyler TJ. Spermine increases paired-pulse facilitation in area CA1 of hippocampus in a calcium-dependent manner. Brain Res. 1995 Aug 21; 689(2):189-96. PMID: 7583322.
      Citations: 7     Fields:    Translation:AnimalsCells
    26. Lipton P, Aitken PG, Dudek FE, Eskessen K, Espanol MT, Ferchmin PA, Kelly JB, Kreisman NR, Landfield PW, Larkman PM, et al. Making the best of brain slices: comparing preparative methods. J Neurosci Methods. 1995 Jun; 59(1):151-6. PMID: 7475245.
      Citations: 17     Fields:    Translation:AnimalsCells
    27. Gonzalez-Lima F, Ferchmin PA, Eterovic VA, Gonzalez-Lima EM. Metabolic activation of the brain of young rats after exposure to environmental complexity. Dev Psychobiol. 1994 Sep; 27(6):343-51. PMID: 8001724.
      Citations: 6     Fields:    Translation:Animals
    28. DiScenna PG, Ferchmin PA, Eterovic VA, Teyler TJ. Spermine depresses NMDA, K/AMPA and GABAA-mediated synaptic transmission in the rat hippocampal slice preparation. Brain Res. 1994 Jun 06; 647(2):353-6. PMID: 7922511.
      Citations: 7     Fields:    Translation:AnimalsCells
    29. Ferchmin PA, Rivera E, Eterovic VA. alpha-Difluoromethylornithine does not antagonize the behavioral effects of putrescine. Pharmacol Biochem Behav. 1993 Aug; 45(4):967-71. PMID: 8415838.
      Citations: 3     Fields:    Translation:Animals
    30. Eterovic VA, Hann RM, Ferchmin PA, Rodriguez AD, Li L, Lee YH, McNamee MG. Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor. Cell Mol Neurobiol. 1993 Apr; 13(2):99-110. PMID: 8102324.
      Citations: 8     Fields:    Translation:AnimalsCells
    31. Eterovic VA, Li L, Ferchmin PA, Lee YH, Hann RM, Rodriguez AD, McNamee MG. The ion channel of muscle and electric organ acetylcholine receptors: differing affinities for noncompetitive inhibitors. Cell Mol Neurobiol. 1993 Apr; 13(2):111-21. PMID: 8394213.
      Citations: 3     Fields:    Translation:AnimalsCells
    32. Ferchmin PA, DiScenna P, Borroni AM, Morales Velez M, Rivera EM, Teyler TJ. alpha-Difluoromethylornithine decreases inhibitory transmission in hippocampal slices independently of its inhibitory effect on ornithine decarboxylase. Brain Res. 1993 Jan 22; 601(1-2):95-102. PMID: 8094315.
      Citations:    Fields:    Translation:AnimalsCells
    33. Szczawinska K, Ferchmin PA, Hann RM, Eterovic VA. Electric organ polyamines and their effects on the acetylcholine receptor. Cell Mol Neurobiol. 1992 Apr; 12(2):95-106. PMID: 1600557.
      Citations: 6     Fields:    Translation:AnimalsCells
    34. Ferchmin PA. Are polyamines modulators of the CNS? Ann N Y Acad Sci. 1991; 627:354-8. PMID: 1679312.
      Citations:    Fields:    Translation:AnimalsCells
    35. Ferchmin PA, Eterovic VA. Putrescine decreases exploration of a black and white maze. Pharmacol Biochem Behav. 1990 Nov; 37(3):445-9. PMID: 2087486.
      Citations: 2     Fields:    Translation:Animals
    36. Ferchmin PA, Eterovic VA. Experience affects cortical but not subcortical polyamines. Pharmacol Biochem Behav. 1990 Jan; 35(1):255-8. PMID: 2107554.
      Citations: 1     Fields:    Translation:Animals
    37. Eterovic VA, Escalona de Motta G, Hann RM, Lasalde JA, Prieto JA, Ferchmin PA. Positive modulators of muscle acetylcholine receptor. J Recept Res. 1989; 9(2):107-25. PMID: 2787401.
      Citations: 2     Fields:    Translation:Animals
    38. Ferchmin PA, Eterovic VA. Role of polyamines in experience-dependent brain plasticity. Pharmacol Biochem Behav. 1987 Feb; 26(2):341-9. PMID: 2437595.
      Citations: 4     Fields:    Translation:Animals
    39. Ferchmin PA, Eterovic VA. Forty minutes of experience increase the weight and RNA content of cerebral cortex in periadolescent rats. Dev Psychobiol. 1986 Nov; 19(6):511-9. PMID: 2433174.
      Citations: 3     Fields:    Translation:Animals
    40. Eterovic VA, Ferchmin PA. Interaction with objects by group-living Saimiri sciureus. P R Health Sci J. 1985 Dec; 4(3):121-5. PMID: 3837910.
      Citations:    Fields:    Translation:Animals
    41. del Castillo J, Escalona de Motta G, Eterovic VA, Ferchmin PA. Succinyl derivatives of N-tris (hydroxymethyl) methyl-2-aminoethane sulphonic acid: their effects on the frog neuromuscular junction. Br J Pharmacol. 1985 Feb; 84(2):275-88. PMID: 3872147.
      Citations: 1     Fields:    Translation:AnimalsCells
    42. Ferchmin PA, Eterovic VA, Levin LE. Genetic learning deficiency does not hinder environment-dependent brain growth. Physiol Behav. 1980 Jan; 24(1):45-50. PMID: 7384250.
      Citations: 2     Fields:    Translation:Animals
    43. Ferchmin PA, Eterovic VA. Mechanism of brain growth by environmental stimulation. Science. 1979 Aug 03; 205(4405):522. PMID: 451619.
      Citations:    Fields:    Translation:Animals
    44. Eterovic VA, Ferchmin PA. Predicted secondary structure of snake venom toxins from their primary structures. Int J Pept Protein Res. 1977; 10(3):245-51. PMID: 914428.
      Citations:    Fields:    Translation:Cells
    45. Ferchmin PA, Morimoto H, Bennett EL. Effect of GTP and other nucleoside triphosphates on GMP incorporation by isolated cortical nuclei. J Neurochem. 1975 Oct; 25(4):437-43. PMID: 1151378.
      Citations: 3     Fields:    Translation:AnimalsCells
    46. Ferchmin PA, Bennett EL. Direct contact with enriched environment is required to alter cerebral weights in rats. J Comp Physiol Psychol. 1975 Jan; 88(1):360-7. PMID: 1120811.
      Citations: 10     Fields:    Translation:Animals
    47. Morimoto H, Ferchmin PA, Bennett EL. Spectrophotometric analysis of RNA and DNA using cetyltrimethylammonium bromide. Anal Biochem. 1974 Dec; 62(2):436-48. PMID: 4441742.
      Citations: 12     Fields:    Translation:AnimalsCells
    48. Eterovic VA, Ferchmin PA. Interaction of environment and injections on brain weight in rats. Dev Psychobiol. 1974 Nov; 7(6):515-7. PMID: 4448305.
      Citations: 1     Fields:    Translation:Animals
    49. Eterovic VA, Ferchmin PA, Caputto R. Influence of rat exploratory activity on brain oxygen uptake in vitro. Int J Neurosci. 1973 Mar; 5(3):133-7. PMID: 4696816.
      Citations:    Fields:    Translation:Animals
    50. Ferchmin PA, Eterovic VA, Caputto R. Studies of brain weight and RNA content after short periods of exposure to environmental complexity. Brain Res. 1970 May 20; 20(1):49-57. PMID: 5444768.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
      Citations: 1     Fields:    Translation:AnimalsCells
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