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Nazarius S. Lamango

TitleProfessor of Medicinal Chemistry
Faculty RankProfessor
InstitutionFlorida A&M University
DepartmentCoPPS, IPH Pharmaceutical Sciences
Address1415 S Martin Luther King Jr Blvd
Tallahassee FL 32307
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Asong GM, Amissah F, Voshavar C, Nkembo AT, Ntantie E, Lamango NS, Ablordeppey SY. A Mechanistic Investigation on the Anticancer Properties of SYA013, a Homopiperazine Analogue of Haloperidol with Activity against Triple Negative Breast Cancer Cells. ACS Omega. 2020 Dec 29; 5(51):32907-32918. PMID: 33403252.
    2. Lamango NS, Nkembo AT, Ntantie E, Tawfeeq N. Polyisoprenylated Cysteinyl Amide Inhibitors: A Novel Approach to Controlling Cancers with Hyperactive Growth Signaling. Curr Med Chem. 2020 Nov 11. PMID: 33176634.
      Citations:    Fields:    
    3. Asong G, Zhu XY, Bricker B, Andey T, Amissah F, Lamango N, Ablordeppey SY. New analogs of SYA013 as sigma-2 ligands with anticancer activity. Bioorg Med Chem. 2019 06 15; 27(12):2629-2636. PMID: 30987780.
      Citations: 1     Fields:    Translation:HumansCells
    4. Nkembo AT, Amissah F, Ntantie E, Poku RA, Salako OO, Ikpatt OF, Lamango NS. Polyisoprenylated Cysteinyl Amide Inhibitors Deplete K-Ras and Induce Caspase-dependent Apoptosis in Lung Cancer Cells. Curr Cancer Drug Targets. 2019; 19(10):838-851. PMID: 30914025.
      Citations: 1     Fields:    Translation:HumansCells
    5. Ntantie E, Allen MJ, Fletcher J, Nkembo AT, Lamango NS, Ikpatt OF. Suppression of focal adhesion formation may account for the suppression of cell migration, invasion and growth of non-small cell lung cancer cells following treatment with polyisoprenylated cysteinyl amide inhibitors. Oncotarget. 2018 May 25; 9(40):25781-25795. PMID: 29899821.
      Citations: 2     Fields:    
    6. Poku RA, Salako OO, Amissah F, Nkembo AT, Ntantie E, Lamango NS. Polyisoprenylated cysteinyl amide inhibitors induce caspase 3/7- and 8-mediated apoptosis and inhibit migration and invasion of metastatic prostate cancer cells. Am J Cancer Res. 2017; 7(7):1515-1527. PMID: 28744401.
    7. Ntantie E, Fletcher J, Amissah F, Salako OO, Nkembo AT, Poku RA, Ikpatt FO, Lamango NS. Polyisoprenylated cysteinyl amide inhibitors disrupt actin cytoskeleton organization, induce cell rounding and block migration of non-small cell lung cancer. Oncotarget. 2017 May 09; 8(19):31726-31744. PMID: 28423648.
      Citations: 7     Fields:    Translation:HumansCells
    8. Nkembo AT, Salako O, Poku RA, Amissah F, Ntantie E, Flores-Rozas H, Lamango NS. Disruption of actin filaments and suppression of pancreatic cancer cell viability and migration following treatment with polyisoprenylated cysteinyl amides. Am J Cancer Res. 2016; 6(11):2532-2546. PMID: 27904769.
    9. Nkembo AT, Ntantie E, Salako OO, Amissah F, Poku RA, Latinwo LM, Lamango NS. The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety. Oncotarget. 2016 Oct 18; 7(42):68194-68205. PMID: 27626690.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    10. Sierra-Fonseca JA, Najera O, Martinez-Jurado J, Walker EM, Varela-Ramirez A, Khan AM, Miranda M, Lamango NS, Roychowdhury S. Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gß?-microtubule interaction. BMC Neurosci. 2014 Dec 31; 15:132. PMID: 25552352.
      Citations: 11     Fields:    Translation:AnimalsCells
    11. Poku RA, Amissah F, Duverna R, Aguilar BJ, Kiros GE, Lamango NS. Polyisoprenylated methylated protein methyl esterase as a putative drug target for androgen-insensitive prostate cancer. Ecancermedicalscience. 2014; 8:459. PMID: 25228915.
    12. Sampson D, Bricker B, Zhu XY, Peprah K, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Further evaluation of the tropane analogs of haloperidol. Bioorg Med Chem Lett. 2014 Sep 01; 24(17):4294-7. PMID: 25070422.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Aguilar BJ, Nkembo AT, Duverna R, Poku RA, Amissah F, Ablordeppey SY, Lamango NS. Polyisoprenylated methylated protein methyl esterase: a putative biomarker and therapeutic target for pancreatic cancer. Eur J Med Chem. 2014 Jun 23; 81:323-33. PMID: 24852279.
      Citations: 5     Fields:    Translation:HumansCells
    14. Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem. 2014 Jun 15; 22(12):3105-14. PMID: 24800940.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    15. Amissah F, Duverna R, Aguilar BJ, Poku RA, Kiros GE, Lamango NS. Polyisoprenylated methylated protein methyl esterase overexpression and hyperactivity promotes lung cancer progression. Am J Cancer Res. 2014; 4(2):116-34. PMID: 24660102.
    16. Amissah F, Duverna R, Aguilar BJ, Poku RA, Lamango NS. Polyisoprenylated methylated protein methyl esterase is both sensitive to curcumin and overexpressed in colorectal cancer: implications for chemoprevention and treatment. Biomed Res Int. 2013; 2013:416534. PMID: 23936796.
      Citations: 7     Fields:    Translation:HumansCells
    17. Ayuk-Takem L, Amissah F, Aguilar BJ, Lamango NS. Inhibition of polyisoprenylated methylated protein methyl esterase by synthetic musks induces cell degeneration. Environ Toxicol. 2014 Apr; 29(4):466-77. PMID: 22489002.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    18. Amissah F, Taylor S, Duverna R, Ayuk-Takem LT, Lamango NS. Regulation of polyisoprenylated methylated protein methyl esterase by polyunsaturated fatty acids and prostaglandins. Eur J Lipid Sci Technol. 2011 Nov; 113(11):1321-1331. PMID: 22468134.
    19. Aguilar B, Amissah F, Duverna R, Lamango NS. Polyisoprenylation potentiates the inhibition of polyisoprenylated methylated protein methyl esterase and the cell degenerative effects of sulfonyl fluorides. Curr Cancer Drug Targets. 2011 Jul; 11(6):752-62. PMID: 21599633.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    20. Lamango NS, Duverna R, Zhang W, Ablordeppey SY. Porcine Liver Carboxylesterase Requires Polyisoprenylation for High Affinity Binding to Cysteinyl Substrates. Open Enzym Inhib J. 2009 Jan 01; 2:12-27. PMID: 20664805.
    21. Oboh OT, Lamango NS. Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase. J Biochem Mol Toxicol. 2008 Feb; 22(1):51-62. PMID: 18273909.
      Citations: 16     Fields:    Translation:AnimalsCells
    22. Lee DC, Womble TA, Mason CW, Jackson IM, Lamango NS, Severs WB, Palm DE. 6-Hydroxydopamine induces cystatin C-mediated cysteine protease suppression and cathepsin D activation. Neurochem Int. 2007 Mar; 50(4):607-18. PMID: 17241700.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Isaac RE, Lamango NS, Ekbote U, Taylor CA, Hurst D, Weaver RJ, Carhan A, Burnham S, Shirras AD. Angiotensin-converting enzyme as a target for the development of novel insect growth regulators. Peptides. 2007 Jan; 28(1):153-62. PMID: 17157962.
      Citations: 11     Fields:    Translation:Animals
    24. Shepherd KR, Lee ES, Schmued L, Jiao Y, Ali SF, Oriaku ET, Lamango NS, Soliman KF, Charlton CG. The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice. Pharmacol Biochem Behav. 2006 Mar; 83(3):349-59. PMID: 16580056.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    25. Lamango NS. Liver prenylated methylated protein methyl esterase is an organophosphate-sensitive enzyme. J Biochem Mol Toxicol. 2005; 19(5):347-57. PMID: 16292756.
      Citations: 12     Fields:    Translation:AnimalsCells
    26. Lee ES, Chen H, Shepherd KR, Lamango NS, Soliman KF, Charlton CG. Inhibitory effects of lysophosphatidylcholine on the dopaminergic system. Neurochem Res. 2004 Jul; 29(7):1333-42. PMID: 15202762.
      Citations: 2     Fields:    Translation:AnimalsCells
    27. Lee ES, Chen H, Shepherd KR, Lamango NS, Soliman KF, Charlton CG. The inhibitory role of methylation on the binding characteristics of dopamine receptors and transporter. Neurosci Res. 2004 Mar; 48(3):335-44. PMID: 15154679.
      Citations: 5     Fields:    Translation:AnimalsCells
    28. Lamango NS, Ayuk-Takem LT, Nesby R, Zhao WQ, Charlton CG. Inhibition mechanism of S-adenosylmethionine-induced movement deficits by prenylcysteine analogs. Pharmacol Biochem Behav. 2003 Dec; 76(3-4):433-42. PMID: 14643842.
      Citations: 5     Fields:    Translation:AnimalsCells
    29. Zhao WQ, Williams Z, Shepherd KR, Reuben JS, Lee ES, Darling-Reed S, Lamango N, Soliman KF, Charlton CG. S-adenosyl-methionine-induced apoptosis in PC12 cells. J Neurosci Res. 2002 Aug 15; 69(4):519-29. PMID: 12210845.
      Citations: 6     Fields:    Translation:AnimalsCells
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