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Tiffany W. Ardley

TitleDirector and Assistant Professor
Faculty RankAssistant Professor
InstitutionFlorida A&M University
DepartmentCoPPS, IPH Pharmaceutical Sciences
Address1415 S Martin Luther King Jr Blvd
Tallahassee FL 32307
Phone8505993774
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    Collapse Biography 
    Collapse awards and honors
    2009Junior Faculty Fellow, Florida A&M University
    2009 - 2010Most Outstanding Community Service, Florida A&M University
    2010Faculty Scholar in Cancer Research, American Association for Cancer Research
    2011Teacher of the Year in Basic Pharmaceutical Sciences, Florida A&M University
    2012Collaborative Enhancement Award, RCMI/RTRN
    2012Minority Serving Institution Faculty Scholar in Cancer Research , American Association for Cancer Research

    Collapse Overview 
    Collapse overview
    I began my research interests as an undergraduate and was drawn to medicinal chemistry because of the opportunity to design and develop compounds to target diseases.

    My graduate work focused on the design and development of novel compounds for inflammatory disorders. Because some of the mediators in inflammation are also found in breast cancer, the compounds that I designed and developed were tested for their effect in some breast cancer cells and some were found to be inhibitory. As I continue to synthesize more compounds in this area, I am also interested in the possibility of these compounds having inhibitory activities in prostate cancer cells and other cancer cells as well because of the presence of some of the same mediators. To this day, I continue to design and develop compounds in an effort to explore these effects as well as the possible mechanism by which they are inhibitory. In addition to cancer research, I am also interested in trying to develop agents that would inhibit the growth and formation of uterine fibroids. Prostate cancer and uterine fibroid research are especially interesting to me because African American men and women are disproportionately affected, respectively.

    As a graduate student, post doctoral research fellow and now as an assistant professor, I have mentored graduate, undergraduate and high school students in research. Many of these students are on the path to research careers. I enjoy mentoring and am always looking for mentoring opportunities because a great mentor is what led me to research.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nkrumah-Elie YM, Reuben JS, Hudson AM, Taka E, Badisa R, Ardley T, Israel B, Sadrud-Din SY, Oriaku ET, Darling-Reed SF. The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells. Nutr Cancer. 2012; 64(7):1112-21. PMID: 23006051.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    2. Nkrumah-Elie YM, Reuben JS, Hudson A, Taka E, Badisa R, Ardley T, Israel B, Sadrud-Din SY, Oriaku E, Darling-Reed SF. Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells. Food Chem Toxicol. 2012 Jul; 50(7):2524-30. PMID: 22525868.
      Citations: 17     Fields:    Translation:HumansCells
    3. Ghaffari MA, Ardley TW, Gangapuram M, Redda KK. SYNTHESIS OF N-SUBSTITUTED CARBONYLAMINO-1,2,3,6-TETRAHYDROPYRIDINES AS POTENTIAL ANTI-INFLAMMATORY AGENTS. Synth Commun. 2011; 41(7):2615-2623. PMID: 22654150.
      Citations:    
    4. Mochona B, Le L, Gangapuram M, Mateeva N, Ardley T, Redda KK. Synthesis of 2-(N-Benzylpyrrolyl)-benzimidazoles Using Polyphosphoric Acid Prompted Cyclocondensation. J Heterocycl Chem. 2010 11 01; 47(6):1367-1371. PMID: 21423826.
      Citations:    
    5. Okoroa CO, Wilsonb TL, Redda KK. Conformational analysis and molecular properties of N-(substituted phenyl-carbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyridines. Curr Med Chem. 2003 Feb; 10(4):313-20. PMID: 12570704.
      Citations: 2     Fields:    Translation:Cells
    6. Mochona B, Wilson T, Redda K. Synthesis and anti-inflammatory activities of N-benzoylamino-1,2,3,6-tetrahydropyridine analogs. Drugs Exp Clin Res. 2003; 29(4):131-40. PMID: 15018303.
      Citations: 3     Fields:    Translation:Animals
    7. Yoon K, Wilson T, Williams S, Redda K. Synthesis and pharmacological evaluations of N-(substituted benzoylamino)-5-carbethoxymethyl-1,2,3,6-tetrahydropyridines as potential antiinflammatory agents. Drugs Exp Clin Res. 2000; 26(3):73-82. PMID: 10941599.
      Citations: 3     Fields:    Translation:AnimalsCells
    8. Wilson T, Onubogu U, Kode R, Redda K. The pharmacological evaluations of some N-[pyridyl-(phenyl)carbonylamino]hydroxypropyl-1,2,3,6-tetrahy dropyridi nes as potential antiinflammatory agents. Drugs Exp Clin Res. 1998; 24(4):165-72. PMID: 10051962.
      Citations: 3     Fields:    Translation:Animals
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