Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats.

Xu N, Zhang Y, Doycheva DM, Ding Y, Zhang Y, Tang J, Guo H, Zhang JH. Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats. Neuropharmacology. 2018 05 01; 133:415-428.

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subject areas

Adaptor Proteins, Signal Transducing
Adiponectin
Animals
Animals, Newborn
Apoptosis
Body Weight
Brain Infarction
Caspase 3
Disease Models, Animal
Dose-Response Relationship, Drug
Escape Reaction
Female
Fluoresceins
Gene Expression Regulation
Hypoxia-Ischemia, Brain
In Situ Nick-End Labeling
Male
Nerve Tissue Proteins
Neurologic Examination
Neurons
Protein Kinases
Rats
Rats, Sprague-Dawley
Receptors, Adiponectin
Reflex
RNA, Small Interfering
Signal Transduction
Statistics, Nonparametric
Swimming
Time Factors

authors with profiles

John Zhang

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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