Amyloid Precursor Protein Secretases
"Amyloid Precursor Protein Secretases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.
| Descriptor ID |
D053829
|
| MeSH Number(s) |
D08.811.277.656.300.032
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amyloid Precursor Protein Secretases".
Below are MeSH descriptors whose meaning is more specific than "Amyloid Precursor Protein Secretases".
This graph shows the total number of publications written about "Amyloid Precursor Protein Secretases" by people in this website by year, and whether "Amyloid Precursor Protein Secretases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 3 | 1 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amyloid Precursor Protein Secretases" by people in Profiles.
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Neupane RP, Parrish SM, Neupane JB, Yoshida WY, Yip MLR, Turkson J, Harper MK, Head JD, Williams PG. Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge Dactylospongia elegans. Mar Drugs. 2019 Jul 19; 17(7).
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Kapur N, Mir H, Sonpavde GP, Jain S, Bae S, Lillard JW, Singh S. Prostate cancer cells hyper-activate CXCR6 signaling by cleaving CXCL16 to overcome effect of docetaxel. Cancer Lett. 2019 07 10; 454:1-13.
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Jean-Louis T, Rockwell P, Figueiredo-Pereira ME. Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by a- and ?-secretases: relevance to Alzheimer's disease. Neurobiol Aging. 2018 02; 62:130-145.
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Wang W, Moerman-Herzog AM, Slaton A, Barger SW. Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2. Neurobiol Aging. 2017 01; 49:145-153.
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Zhang ZH, Chen C, Wu QY, Zheng R, Liu Q, Ni JZ, Hoffmann PR, Song GL. Selenomethionine reduces the deposition of beta-amyloid plaques by modulating ?-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease. Metallomics. 2016 08 01; 8(8):782-9.
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Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71.
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Dai J, Parrish SM, Yoshida WY, Yip MLR, Turkson J, Kelly M, Williams P. Bromotyrosine-derived metabolites from an Indonesian marine sponge in the family Aplysinellidae (Order Verongiida). Bioorg Med Chem Lett. 2016 Jan 15; 26(2):499-504.
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Mir H, Singh R, Kloecker GH, Lillard JW, Singh S. CXCR6 expression in non-small cell lung carcinoma supports metastatic process via modulating metalloproteinases. Oncotarget. 2015 Apr 30; 6(12):9985-98.
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Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA. Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression. J Virol. 2015 Apr; 89(7):3723-36.
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Yan X, Lin J, Talabattula VA, Mu?mann C, Yang F, Wree A, Rolfs A, Luo J. ADAM10 negatively regulates neuronal differentiation during spinal cord development. PLoS One. 2014; 9(1):e84617.