"Apolipoprotein B-100" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 513-kDa protein synthesized in the LIVER. It serves as the major structural protein of low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). It is the ligand for the LDL receptor (RECEPTORS, LDL) that promotes cellular binding and internalization of LDL particles.
| Descriptor ID |
D053299
|
| MeSH Number(s) |
D10.532.091.300.249 D12.776.070.400.300.249 D12.776.521.120.300.249
|
| Concept/Terms |
Apolipoprotein B-100- Apolipoprotein B-100
- Apolipoprotein B 100
- ApoB-100
- ApoB 100
- Apo B-100
- Apo B 100
- Apo-B-100
|
Below are MeSH descriptors whose meaning is more general than "Apolipoprotein B-100".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein B-100".
This graph shows the total number of publications written about "Apolipoprotein B-100" by people in this website by year, and whether "Apolipoprotein B-100" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Apolipoprotein B-100" by people in Profiles.
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Khera AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X, van Leeuwen EM, Natarajan P, Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N, Nomura A, Kessler T, Duga S, Bis JC, van Duijn CM, Cupples LA, Psaty B, Rader DJ, Danesh J, Schunkert H, McPherson R, Farrall M, Watkins H, Lander E, Wilson JG, Correa A, Boerwinkle E, Merlini PA, Ardissino D, Saleheen D, Gabriel S, Kathiresan S. Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. J Am Coll Cardiol. 2016 06 07; 67(22):2578-89.
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Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease. Hum Genet. 2015 Aug; 134(8):895-904.
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Vaiopoulou A, Gazouli M, Papadopoulou A, Anagnostopoulos AK, Karamanolis G, Theodoropoulos GE, M'Koma A, Tsangaris GT. Serum protein profiling of adults and children with Crohn disease. J Pediatr Gastroenterol Nutr. 2015 Jan; 60(1):42-7.
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Nerurkar PV, Lee YK, Motosue M, Adeli K, Nerurkar VR. Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. Br J Nutr. 2008 Oct; 100(4):751-9.
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Yee WL, Wang Q, Agdinaoay T, Dang K, Chang H, Grandinetti A, Franke AA, Theriault A. Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells. Mol Cell Biochem. 2002 Jan; 229(1-2):85-92.