Protein-Arginine N-Methyltransferases

"Protein-Arginine N-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.

Descriptor ID	D011484
MeSH Number(s)	D08.811.913.555.500.800.750
Concept/Terms	Protein-Arginine N-Methyltransferases Protein-Arginine N-Methyltransferases N-Methyltransferases, Protein-Arginine Protein Arginine N Methyltransferases Protein Arginine Methyltransferase Arginine Methyltransferase, Protein Methyltransferase, Protein Arginine Protein Methyltransferase I Protein-Arginine N-Methyltransferase N-Methyltransferase, Protein-Arginine Protein Arginine N Methyltransferase Arginine Methylase Protein Methylase I Histone-Arginine N-Methyltransferase Histone-Arginine N-Methyltransferase Histone Arginine N Methyltransferase N-Methyltransferase, Histone-Arginine Myelin Basic Protein (Arginine) Methyltransferase Myelin Basic Protein (Arginine) Methyltransferase (Myelin Basic Protein)-Arginine N-Methyltransferase

Below are MeSH descriptors whose meaning is more general than "Protein-Arginine N-Methyltransferases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
One-Carbon Group Transferases [D08.811.913.555]
Methyltransferases [D08.811.913.555.500]
Protein Methyltransferases [D08.811.913.555.500.800]
Protein-Arginine N-Methyltransferases [D08.811.913.555.500.800.750]

Below are MeSH descriptors whose meaning is related to "Protein-Arginine N-Methyltransferases".

Below are MeSH descriptors whose meaning is more specific than "Protein-Arginine N-Methyltransferases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein-Arginine N-Methyltransferases" by people in this website by year, and whether "Protein-Arginine N-Methyltransferases" was a major or minor topic of these publications.

Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2009 and 2015 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2009	1	1
2015	1	1
2019	1	1

Below are the most recent publications written about "Protein-Arginine N-Methyltransferases" by people in Profiles.

Qin M, Fan W, Li L, Xu T, Zhang H, Chen F, Man J, Kombe AJK, Zhang J, Shi Y, Yao X, Yang Z, Hou Z, Ruan K, Liu D. PRMT1 and TDRD3 promote stress granule assembly by rebuilding the protein-RNA interaction network. Int J Biol Macromol. 2024 Oct; 277(Pt 3):134411.

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Fedoriw A, Rajapurkar SR, O'Brien S, Gerhart SV, Mitchell LH, Adams ND, Rioux N, Lingaraj T, Ribich SA, Pappalardi MB, Shah N, Laraio J, Liu Y, Butticello M, Carpenter CL, Creasy C, Korenchuk S, McCabe MT, McHugh CF, Nagarajan R, Wagner C, Zappacosta F, Annan R, Concha NO, Thomas RA, Hart TK, Smith JJ, Copeland RA, Moyer MP, Campbell J, Stickland K, Mills J, Jacques-O'Hagan S, Allain C, Johnston D, Raimondi A, Porter Scott M, Waters N, Swinger K, Boriack-Sjodin A, Riera T, Shapiro G, Chesworth R, Prinjha RK, Kruger RG, Barbash O, Mohammad HP. Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss. Cancer Cell. 2019 07 08; 36(1):100-114.e25.

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Chan-Penebre E, Kuplast KG, Majer CR, Boriack-Sjodin PA, Wigle TJ, Johnston LD, Rioux N, Munchhof MJ, Jin L, Jacques SL, West KA, Lingaraj T, Stickland K, Ribich SA, Raimondi A, Scott MP, Waters NJ, Pollock RM, Smith JJ, Barbash O, Pappalardi M, Ho TF, Nurse K, Oza KP, Gallagher KT, Kruger R, Moyer MP, Copeland RA, Chesworth R, Duncan KW. A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat Chem Biol. 2015 Jun; 11(6):432-7.

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Selvi BR, Batta K, Kishore AH, Mantelingu K, Varier RA, Balasubramanyam K, Pradhan SK, Dasgupta D, Sriram S, Agrawal S, Kundu TK. Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17. J Biol Chem. 2010 Mar 05; 285(10):7143-52.

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Estrella LA, Wilkinson MF, Gonz?lez CI. The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae. J Mol Biol. 2009 Dec 04; 394(3):410-22.

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