Wiskott-Aldrich Syndrome Protein Family
"Wiskott-Aldrich Syndrome Protein Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
| Descriptor ID |
D051300
|
| MeSH Number(s) |
D05.750.078.730.912 D12.776.220.525.912
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome Protein Family".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome Protein Family".
This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in this website by year, and whether "Wiskott-Aldrich Syndrome Protein Family" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in Profiles.
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Rawe VY, Payne C, Navara C, Schatten G. WAVE1 intranuclear trafficking is essential for genomic and cytoskeletal dynamics during fertilization: cell-cycle-dependent shuttling between M-phase and interphase nuclei. Dev Biol. 2004 Dec 15; 276(2):253-67.
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Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52.