"Synaptotagmins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of vesicular transport proteins characterized by an N-terminal transmembrane region and two C-terminal calcium-binding domains.
| Descriptor ID |
D050857
|
| MeSH Number(s) |
D12.776.157.125.825 D12.776.543.990.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synaptotagmins".
Below are MeSH descriptors whose meaning is more specific than "Synaptotagmins".
This graph shows the total number of publications written about "Synaptotagmins" by people in this website by year, and whether "Synaptotagmins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptotagmins" by people in Profiles.
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Zhang P, Rumschitzki D, Edwards RH. High-speed imaging reveals the bimodal nature of dense core vesicle exocytosis. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2214897120.
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Guan Z, Bykhovskaia M, Jorquera RA, Sutton RB, Akbergenova Y, Littleton JT. A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion. Elife. 2017 09 12; 6.
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Amaya MJ, Oliveira AG, Schroeder LK, Allgeyer ES, Bewersdorf J, Nathanson MH. Apical localization of inositol 1,4,5-trisphosphate receptors is independent of extended synaptotagmins in hepatocytes. PLoS One. 2014; 9(12):e114043.
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Jorquera RA, Huntwork-Rodriguez S, Akbergenova Y, Cho RW, Littleton JT. Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity. J Neurosci. 2012 Dec 12; 32(50):18234-45.
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Barber CF, Jorquera RA, Melom JE, Littleton JT. Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains. J Cell Biol. 2009 Oct 19; 187(2):295-310.
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Akbergenova Y, Bykhovskaia M. Stimulation-induced formation of the reserve pool of vesicles in Drosophila motor boutons. J Neurophysiol. 2009 May; 101(5):2423-33.