"Troponin C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Descriptor ID |
D019209
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MeSH Number(s) |
D05.500.945.900 D05.750.078.730.825.900 D12.776.157.125.900 D12.776.210.500.910.900 D12.776.220.525.825.900
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Troponin C".
Below are MeSH descriptors whose meaning is more specific than "Troponin C".
This graph shows the total number of publications written about "Troponin C" by people in this website by year, and whether "Troponin C" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Troponin C" by people in Profiles.
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Badr MA, Pinto JR, Davidson MW, Chase PB. Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C. PLoS One. 2016; 11(10):e0164222.
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Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014 Oct 03; 5:5092.
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Massom L, Lee H, Jarrett HW. Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C. Biochemistry. 1990 Jan 23; 29(3):671-81.