TNF Receptor-Associated Factor 6

"TNF Receptor-Associated Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signalling and activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES.

Descriptor ID	D048029
MeSH Number(s)	D12.644.360.024.500.968 D12.776.157.057.500.968 D12.776.476.024.500.968
Concept/Terms	TNF Receptor-Associated Factor 6 TNF Receptor-Associated Factor 6 TNF Receptor Associated Factor 6 TRAF-6 Protein TRAF 6 Protein TRAF6

Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 6".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.644.360.024.500]
TNF Receptor-Associated Factor 6 [D12.644.360.024.500.968]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.157.057.500]
TNF Receptor-Associated Factor 6 [D12.776.157.057.500.968]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.476.024.500]
TNF Receptor-Associated Factor 6 [D12.776.476.024.500.968]

Below are MeSH descriptors whose meaning is related to "TNF Receptor-Associated Factor 6".

Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 6".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "TNF Receptor-Associated Factor 6" by people in this website by year, and whether "TNF Receptor-Associated Factor 6" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2003 and 2012 and 2013 and 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2012	1	0	1
2013	1	0	1
2016	1	0	1
2020	1	0	1

Below are the most recent publications written about "TNF Receptor-Associated Factor 6" by people in Profiles.

Luo Y, Fang Y, Kang R, Lenahan C, Gamdzyk M, Zhang Z, Okada T, Tang J, Chen S, Zhang JH. Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-?B (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-?B) in a Rat Model of Subarachnoid Hemorrhage. Stroke. 2020 11; 51(11):3320-3331.

View in: PubMed
Lu W, Liu S, Li B, Xie Y, Izban MG, Ballard BR, Sathyanarayana SA, Adunyah SE, Matusik RJ, Chen Z. SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer. Oncogene. 2017 03; 36(10):1364-1373.

View in: PubMed
Ma C, Muranyi M, Chu CH, Zhang J, Chu WM. Involvement of DNA-PKcs in the IL-6 and IL-12 response to CpG-ODN is mediated by its interaction with TRAF6 in dendritic cells. PLoS One. 2013; 8(3):e58072.

View in: PubMed
Namjou B, Choi CB, Harley IT, Alarc?n-Riquelme ME, Kelly JA, Glenn SB, Ojwang JO, Adler A, Kim K, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown EE, Edberg J, Alarc?n GS, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Kim EM, Park SY, Sung YK, Guthridge JM, Merrill JT, Petri M, Ramsey-Goldman R, Vil? LM, Niewold TB, Martin J, Pons-Estel BA, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams AH, Comeau ME, Reveille JD, Kang C, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Bae SC. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9.

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Bharti AC, Takada Y, Shishodia S, Aggarwal BB. Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism. J Biol Chem. 2004 Feb 13; 279(7):6065-76.

View in: PubMed

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