"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
| Descriptor ID |
D020121
|
| MeSH Number(s) |
D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
|
| Concept/Terms |
5' Untranslated Regions- 5' Untranslated Regions
- 5' Untranslated Region
- Region, 5' Untranslated
- Regions, 5' Untranslated
- Untranslated Region, 5'
- Untranslated Regions, 5'
- 5'UTR
- 5'UTRs
- Leader Sequences, mRNA
- Leader Sequence, mRNA
- Sequence, mRNA Leader
- Sequences, mRNA Leader
- mRNA Leader Sequence
- mRNA Leader Sequences
- 5' UTR
- 5' UTRs
- UTR, 5'
- UTRs, 5'
- Leader mRNA Sequences
- Leader mRNA Sequence
- Sequence, Leader mRNA
- Sequences, Leader mRNA
- mRNA Sequence, Leader
- mRNA Sequences, Leader
|
Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".
This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.
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Saha B, Bhardwaj U, Goss DJ. Thermodynamically Favorable Interactions between eIF4E Binding Domain of eIF4GI with Structured 5'-Untranslated Regions Drive Cap-Independent Translation of Selected mRNAs. Biochemistry. 2023 06 06; 62(11):1767-1775.
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Powell P, Bhardwaj U, Goss D. Eukaryotic initiation factor 4F promotes a reorientation of eukaryotic initiation factor 3 binding on the 5' and the 3' UTRs of barley yellow dwarf virus mRNA. Nucleic Acids Res. 2022 05 20; 50(9):4988-4999.
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Haizel SA, Bhardwaj U, Gonzalez RL, Mitra S, Goss DJ. 5'-UTR recruitment of the translation initiation factor eIF4GI or DAP5 drives cap-independent translation of a subset of human mRNAs. J Biol Chem. 2020 08 14; 295(33):11693-11706.
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Bhardwaj U, Powell P, Goss DJ. Eukaryotic initiation factor (eIF) 3 mediates Barley Yellow Dwarf Viral mRNA 3'-5' UTR interactions and 40S ribosomal subunit binding to facilitate cap-independent translation. Nucleic Acids Res. 2019 07 09; 47(12):6225-6235.
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Popik W, Khatua A, Hildreth JEK, Lee B, Alcendor DJ. Phosphorodiamidate morpholino targeting the 5' untranslated region of the ZIKV RNA inhibits virus replication. Virology. 2018 06; 519:77-85.
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Weber GG, Kortmann J, Narberhaus F, Klose KE. RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae. Proc Natl Acad Sci U S A. 2014 Sep 30; 111(39):14241-6.
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Nandety RS, Fofanov VY, Koshinsky H, Stenger DC, Falk BW. Small RNA populations for two unrelated viruses exhibit different biases in strand polarity and proximity to terminal sequences in the insect host Homalodisca vitripennis. Virology. 2013 Jul 20; 442(1):12-9.
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Chandra PK, Kundu AK, Hazari S, Chandra S, Bao L, Ooms T, Morris GF, Wu T, Mandal TK, Dash S. Inhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes. Mol Ther. 2012 Sep; 20(9):1724-36.
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Misra S, Sharma S, Agarwal A, Khedkar SV, Tripathi MK, Mittal MK, Chaudhuri G. Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells. Mol Cancer. 2010 Mar 04; 9:50.
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Shung CY, Sunter G. Regulation of Tomato golden mosaic virus AL2 and AL3 gene expression by a conserved upstream open reading frame. Virology. 2009 Jan 20; 383(2):310-8.