"DNA Polymerase beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA repair enzyme that catalyzes DNA synthesis during base excision DNA repair. EC 2.7.7.7.
| Descriptor ID |
D019951
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.112
|
| Concept/Terms |
DNA Polymerase beta- DNA Polymerase beta
- Polymerase beta, DNA
- DNA Polymerase IV
- IV, DNA Polymerase
- Polymerase IV, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase beta".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase beta".
This graph shows the total number of publications written about "DNA Polymerase beta" by people in this website by year, and whether "DNA Polymerase beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase beta" by people in Profiles.
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Darling-Reed SF, Nkrumah-Elie Y, Ferguson DT, Flores-Rozas H, Mendonca P, Messeha S, Hudson A, Badisa RB, Tilghman SL, Womble T, Day A, Jett M, Hammamieh R, Soliman KFA. Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks. Biomolecules. 2021 09 06; 11(9).
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Li W, Luo Y, Zhang F, Signore AP, Gobbel GT, Simon RP, Chen J. Ischemic preconditioning in the rat brain enhances the repair of endogenous oxidative DNA damage by activating the base-excision repair pathway. J Cereb Blood Flow Metab. 2006 Feb; 26(2):181-98.
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Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Res. 2003 Sep 15; 63(18):5799-807.
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Cabelof DC, Yanamadala S, Raffoul JJ, Guo Z, Soofi A, Heydari AR. Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. DNA Repair (Amst). 2003 Mar 01; 2(3):295-307.
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Cabelof DC, Raffoul JJ, Yanamadala S, Guo Z, Heydari AR. Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo. Carcinogenesis. 2002 Sep; 23(9):1419-25.
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Cabelof DC, Raffoul JJ, Yanamadala S, Ganir C, Guo Z, Heydari AR. Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice. Mutat Res. 2002 Mar 20; 500(1-2):135-45.
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Intano GW, McMahan CA, Walter RB, McCarrey JR, Walter CA. Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity. Nucleic Acids Res. 2001 Mar 15; 29(6):1366-72.
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Pahlavani MA, Vargas DM, Guo Z, Richardson A. Normal immune function in young and old DNA polymerase-beta deficient mice. Immunol Lett. 2000 Apr 03; 72(1):17-21.