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Tracy Womble

TitleAssistant Professor
Faculty RankAssistant Professor
InstitutionFlorida A&M University
DepartmentCoPPS, IPH Pharmaceutical Sciences
Address1415 S Martin Luther King Jr Blvd
L1-146 East Wing
Tallahassee FL 32307
Phone8505612466
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    Tracy A. Womble received a B.S. in Biology from Florida A&M University and later returned to complete his Ph.D in Pharmacology/Toxicology. His dissertation was in the area of stroke induced neurodegerative pathways. His dissertation was titeled, "The Involvement of the Lysosomal Proteases Cathepsin B and Cathepsin D during TNF-a Induced Apoptosis. He later completed his postdoctoral work at the University of South Florida, Department of Neurosurgery in the Center for Aging and Brain Repair. There he studied the use of human umbilical cord blood as a neuroprotective agent following middle cerebral artery occlusion. After completion of the postdoctoral training, Dr. Womble returned to Florida A&M University as a research associate supervising the proteomics and imaging facilities within the FAMU RCMI funded Biotechnology Core to provide and train researchers in the use of data acquisition and analysis of fluorescent and photogenic samples, digital imaging and document production for publication. Dr. Womble also serves as the RTRN and eagle-i liason for the FAMU RCMI. In addition, Dr. Womble also teaches central nervous system drug portion of PDA within the FAMU College of Pharmacy and Pharmaceutical Sciences. The potential therapeutic benefits from human umbilical cord blood (HUCB) cells for the treatment of neurodegenerative diseases are becoming increasingly recognized. The transplantation of HUCB cells into animal stroke models has resulted in neuroprotection, but to date the mechanism of action has been elusive. Dr. Womble is utilizing proteomic approaches to identify a profile of proteins that will provide a better understanding of this elusive endogenous neuroprotective mechanism.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ferguson DT, Taka E, Tilghman SL, Womble T, Redmond BV, Gedeon S, Flores-Rozas H, Reed SL, Soliman KFA, Kanga KJW, Darling-Reed SF. The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells. Int J Mol Sci. 2024 Jan 11; 25(2). PMID: 38255999.
      Citations: 1     Fields:    Translation:HumansAnimals
    2. Messeha SS, Noel S, Zarmouh NO, Womble T, Latinwo LM, Soliman KFA. Involvement of AKT/PI3K Pathway in Sanguinarine's Induced Apoptosis and Cell Cycle Arrest in Triple-negative Breast Cancer Cells. Cancer Genomics Proteomics. 2023 Jul-Aug; 20(4):323-342. PMID: 37400144.
      Citations: 1     Fields:    Translation:HumansCells
    3. Darling-Reed SF, Nkrumah-Elie Y, Ferguson DT, Flores-Rozas H, Mendonca P, Messeha S, Hudson A, Badisa RB, Tilghman SL, Womble T, Day A, Jett M, Hammamieh R, Soliman KFA. Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks. Biomolecules. 2021 09 06; 11(9). PMID: 34572526.
      Citations: 3     Fields:    Translation:HumansCells
    4. Womble TA, Green S, Shahaduzzaman M, Grieco J, Sanberg PR, Pennypacker KR, Willing AE. Monocytes are essential for the neuroprotective effect of human cord blood cells following middle cerebral artery occlusion in rat. Mol Cell Neurosci. 2014 Mar; 59:76-84. PMID: 24472845.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    5. Golden JE, Shahaduzzaman M, Wabnitz A, Green S, Womble TA, Sanberg PR, Pennypacker KR, Willing AE. Human umbilical cord blood cells alter blood and spleen cell populations after stroke. Transl Stroke Res. 2012 Dec; 3(4):491-9. PMID: 23335948.
      Citations: 8     Fields:    
    6. Jiang L, Womble T, Saporta S, Chen N, Sanberg CD, Sanberg PR, Willing AE. Human umbilical cord blood cells decrease microglial survival in vitro. Stem Cells Dev. 2010 Feb; 19(2):221-8. PMID: 19788371.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    7. Ajmo CT, Collier LA, Leonardo CC, Hall AA, Green SM, Womble TA, Cuevas J, Willing AE, Pennypacker KR. Blockade of adrenoreceptors inhibits the splenic response to stroke. Exp Neurol. 2009 Jul; 218(1):47-55. PMID: 19371742.
      Citations: 84     Fields:    Translation:HumansAnimals
    8. Lee DC, Mason CW, Goodman CB, Holder MS, Kirksey OW, Womble TA, Severs WB, Palm DE. Hydrogen peroxide induces lysosomal protease alterations in PC12 cells. Neurochem Res. 2007 Sep; 32(9):1499-510. PMID: 17440810.
      Citations: 5     Fields:    Translation:AnimalsCells
    9. Lee DC, Womble TA, Mason CW, Jackson IM, Lamango NS, Severs WB, Palm DE. 6-Hydroxydopamine induces cystatin C-mediated cysteine protease suppression and cathepsin D activation. Neurochem Int. 2007 Mar; 50(4):607-18. PMID: 17241700.
      Citations: 2     Fields:    Translation:AnimalsCells
    10. Lee DC, Close FT, Goodman CB, Jackson IM, Wight-Mason C, Wells LM, Womble TA, Palm DE. Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure. Neurotoxicology. 2006 Mar; 27(2):260-76. PMID: 16414118.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
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