"Aldosterone Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
Descriptor ID |
D019405
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MeSH Number(s) |
D08.244.453.484.500 D08.244.453.915.050 D08.811.682.690.708.170.425.500 D08.811.682.690.708.170.915.050 D12.776.422.220.453.484.500 D12.776.422.220.453.915.050
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Concept/Terms |
Cytochrome P-450 CYP11B2- Cytochrome P-450 CYP11B2
- Cytochrome P 450 CYP11B2
- Aldosterone Synthase
- Aldosterone Synthase Cytochrome P-450
- Aldosynthase
- Cytochrome P450Aldo
- P450c11AS
- Cytochrome P450 11B2
- Cytochrome P-450c11AS
- Cytochrome P 450c11AS
- CYP11B2
- Steroid 18-Hydroxylase
- Steroid 18 Hydroxylase
- CYP 11B2
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Below are MeSH descriptors whose meaning is more general than "Aldosterone Synthase".
Below are MeSH descriptors whose meaning is more specific than "Aldosterone Synthase".
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