Directed Molecular Evolution
"Directed Molecular Evolution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of generating structural changes with methods of selection. They are also used to examine proposed mechanisms of evolution under in vitro selection conditions.
| Descriptor ID |
D019020
|
| MeSH Number(s) |
E05.393.420.175
|
| Concept/Terms |
Directed Molecular Evolution- Directed Molecular Evolution
- Directed Molecular Evolutions
- Evolution, Directed Molecular
- Evolutions, Directed Molecular
- Molecular Evolutions, Directed
- Molecular Evolution, Directed
- Evolution, Molecular, Directed
In Vitro Molecular Evolution- In Vitro Molecular Evolution
- Laboratory Molecular Evolution
- Evolution, Laboratory Molecular
- Evolutions, Laboratory Molecular
- Laboratory Molecular Evolutions
- Molecular Evolution, Laboratory
- Molecular Evolutions, Laboratory
|
Below are MeSH descriptors whose meaning is more general than "Directed Molecular Evolution".
Below are MeSH descriptors whose meaning is more specific than "Directed Molecular Evolution".
This graph shows the total number of publications written about "Directed Molecular Evolution" by people in this website by year, and whether "Directed Molecular Evolution" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Directed Molecular Evolution" by people in Profiles.
-
Li J, Davis I, Griffith WP, Liu A. Formation of Monofluorinated Radical Cofactor in Galactose Oxidase through Copper-Mediated C-F Bond Scission. J Am Chem Soc. 2020 11 04; 142(44):18753-18757.
-
Brisendine JM, Koder RL. Fast, cheap and out of control--Insights into thermodynamic and informatic constraints on natural protein sequences from de novo protein design. Biochim Biophys Acta. 2016 May; 1857(5):485-492.
-
Hoi H, Howe ES, Ding Y, Zhang W, Baird MA, Sell BR, Allen JR, Davidson MW, Campbell RE. An engineered monomeric Zoanthus sp. yellow fluorescent protein. Chem Biol. 2013 Oct 24; 20(10):1296-304.
-
Cantor JR, Yoo TH, Dixit A, Iverson BL, Forsthuber TG, Georgiou G. Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1272-7.
-
Mukhopadhyay R, Zhou Y, Rosen BP. Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase. J Biol Chem. 2003 Jul 04; 278(27):24476-80.