Complement C3-C5 Convertases
"Complement C3-C5 Convertases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue.
| Descriptor ID |
D050577
|
| MeSH Number(s) |
D12.776.124.486.274.045.387
|
| Concept/Terms |
Complement C3-C5 Convertases- Complement C3-C5 Convertases
- C3-C5 Convertases, Complement
- Complement C3 C5 Convertases
- Convertases, Complement C3-C5
- C3-C5 Convertase
- C3 C5 Convertase
- Convertase, C3-C5
Complement C3 Convertases- Complement C3 Convertases
- C3 Convertases, Complement
- Convertases, Complement C3
- Complement 3 Convertase
- Convertase, Complement 3
- C3 Convertase
- Convertase, C3
- C3 Activator
- Activator, C3
- C 3 Convertase
- Convertase, C 3
Complement C5 Convertases- Complement C5 Convertases
- C5 Convertases, Complement
- Convertases, Complement C5
- C5 Convertase
- C5 Cleaving Enzyme
- Complement 5 Convertase
|
Below are MeSH descriptors whose meaning is more general than "Complement C3-C5 Convertases".
Below are MeSH descriptors whose meaning is more specific than "Complement C3-C5 Convertases".
This graph shows the total number of publications written about "Complement C3-C5 Convertases" by people in this website by year, and whether "Complement C3-C5 Convertases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement C3-C5 Convertases" by people in Profiles.
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Hew BE, Pangburn MK, Vogel CW, Fritzinger DC. Identification of intermolecular bonds between human factor B and Cobra Venom Factor important for C3 convertase stability. Toxicon. 2020 Sep; 184:68-77.
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Hew BE, Wehrhahn D, Fritzinger DC, Vogel CW. Hybrid proteins of Cobra Venom Factor and cobra C3: tools to identify functionally important regions in Cobra Venom Factor. Toxicon. 2012 Sep 15; 60(4):632-47.
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Fritzinger DC, Hew BE, Thorne M, Pangburn MK, Janssen BJ, Gros P, Vogel CW. Functional characterization of human C3/cobra venom factor hybrid proteins for therapeutic complement depletion. Dev Comp Immunol. 2009; 33(1):105-16.
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Kock MA, Hew BE, Bammert H, Fritzinger DC, Vogel CW. Structure and function of recombinant cobra venom factor. J Biol Chem. 2004 Jul 16; 279(29):30836-43.