"HIV Protease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.
| Descriptor ID |
D016333
|
| MeSH Number(s) |
D08.811.277.656.074.500.340 D08.811.277.656.300.048.340 D12.776.964.775.375.545.750
|
| Concept/Terms |
HIV Protease- HIV Protease
- Protease, HIV
- p16 pol gene product, HIV
- p16 protease, HIV
- HIV p16 protease
- HIV Proteinase
- HTLV-III Protease
- HTLV III Protease
- Protease, HTLV-III
|
Below are MeSH descriptors whose meaning is more general than "HIV Protease".
Below are MeSH descriptors whose meaning is more specific than "HIV Protease".
This graph shows the total number of publications written about "HIV Protease" by people in this website by year, and whether "HIV Protease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "HIV Protease" by people in Profiles.
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Sep?lveda-Torres LDC, Rishishwar L, Rogers ML, R?os-Olivares E, Boukli N, Jordan IK, Cubano LA. A decade of viral mutations and associated drug resistance in a population of HIV-1+ Puerto Ricans: 2002-2011. PLoS One. 2017; 12(5):e0177452.
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Castro E, Martinez ZS, Seong CS, Cabrera-Espinoza A, Ruiz M, Hernandez Garcia A, Valdez F, Llano M, Echegoyen L. Characterization of New Cationic N,N-Dimethyl[70]fulleropyrrolidinium Iodide Derivatives as Potent HIV-1 Maturation Inhibitors. J Med Chem. 2016 12 22; 59(24):10963-10973.
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Ahmed L, Rasulev B, Turabekova M, Leszczynska D, Leszczynski J. Receptor- and ligand-based study of fullerene analogues: comprehensive computational approach including quantum-chemical, QSAR and molecular docking simulations. Org Biomol Chem. 2013 Sep 21; 11(35):5798-808.
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Toropov AA, Toropova AP, Benfenati E, Leszczynska D, Leszczynski J. SMILES-based optimal descriptors: QSAR analysis of fullerene-based HIV-1 PR inhibitors by means of balance of correlations. J Comput Chem. 2010 Jan 30; 31(2):381-92.
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Toropov AA, Toropova AP, Benfenati E, Leszczynska D, Leszczynski J. InChI-based optimal descriptors: QSAR analysis of fullerene[C60]-based HIV-1 PR inhibitors by correlation balance. Eur J Med Chem. 2010 Apr; 45(4):1387-94.
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Ebalunode JO, Ouyang Z, Liang J, Zheng W. Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques. J Chem Inf Model. 2008 Apr; 48(4):889-901.
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Tirado G, Jove G, Reyes E, Sepulveda G, Yamamura Y, Singh DP, Kumar A. Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART. Virology. 2005 Apr 10; 334(2):299-305.
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Dash C, Sastry M, Rao M. Illustration of HIV-1 protease folding through a molten-globule-like intermediate using an experimental model that implicates alpha-crystallin and calcium ions. Biochemistry. 2005 Mar 15; 44(10):3725-34.
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Tirado G, Jove G, Kumar R, Noel RJ, Reyes E, Sepulveda G, Yamamura Y, Kumar A. Differential virus evolution in blood and genital tract of HIV-infected females: evidence for the involvement of drug and non-drug resistance-associated mutations. Virology. 2004 Jul 01; 324(2):577-86.
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Tirado G, Jove G, Kumar R, Noel RJ, Reyes E, Sepulveda G, Yamamura Y, Kumar A. Compartmentalization of drug resistance-associated mutations in a treatment-naive HIV-infected female. AIDS Res Hum Retroviruses. 2004 Jun; 20(6):684-6.