Oncogene Protein pp60(v-src)
"Oncogene Protein pp60(v-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.
| Descriptor ID |
D015688
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| MeSH Number(s) |
D08.811.913.696.620.682.725.800.472 D12.776.624.664.520.750.760 D12.776.964.700.750.760 D12.776.964.775.750.760
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| Concept/Terms |
Oncogene Protein pp60(v-src)- Oncogene Protein pp60(v-src)
- Oncogene Protein pp60(src)
- Oncogene Protein src
- Protein src, Oncogene
- src, Oncogene Protein
- p60(v-src)
- Phosphoprotein pp60(v-src)
- pp60 v-src
- pp60 v src
- v-src, pp60
- Rous Sarcoma Virus-Transforming Protein pp60(v-src)
- src Oncogene Product pp60
- src Oncogene Protein pp60
- v-src Protein
- v src Protein
- v-src Protein pp60
- Protein pp60, v-src
- pp60, v-src Protein
- v src Protein pp60
- Avian Sarcoma Virus-Transforming Protein
- Avian Sarcoma Virus Transforming Protein
- pp60(v-src)
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Below are MeSH descriptors whose meaning is more general than "Oncogene Protein pp60(v-src)".
Below are MeSH descriptors whose meaning is more specific than "Oncogene Protein pp60(v-src)".
This graph shows the total number of publications written about "Oncogene Protein pp60(v-src)" by people in this website by year, and whether "Oncogene Protein pp60(v-src)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oncogene Protein pp60(v-src)" by people in Profiles.
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Schmid AB, Lagleder S, Gr?wert MA, R?hl A, Hagn F, Wandinger SK, Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J. The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. EMBO J. 2012 Mar 21; 31(6):1506-17.
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Lin R, Martyn KD, Guyette CV, Lau AF, Warn-Cramer BJ. v-Src tyrosine phosphorylation of connexin43: regulation of gap junction communication and effects on cell transformation. Cell Commun Adhes. 2006 Jul-Aug; 13(4):199-216.
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Turkson J, Zhang S, Mora LB, Burns A, Sebti S, Jove R. A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells. J Biol Chem. 2005 Sep 23; 280(38):32979-88.
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Chen X, Hui L, Foster DA, Drain CM. Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells. Biochemistry. 2004 Aug 31; 43(34):10918-29.
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Warn-Cramer BJ, Lin R, Martyn K, Guyette CV, Lau AF. Maintaining connexin43 gap junctional communication in v-Src cells does not alter growth properties associated with the transformed phenotype. Cell Commun Adhes. 2003 Jul-Dec; 10(4-6):299-303.
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Zhong M, Shen Y, Zheng Y, Joseph T, Jackson D, Foster DA. Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun. 2003 Mar 14; 302(3):615-9.
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Cottrell GT, Lin R, Warn-Cramer BJ, Lau AF, Burt JM. Mechanism of v-Src- and mitogen-activated protein kinase-induced reduction of gap junction communication. Am J Physiol Cell Physiol. 2003 Feb; 284(2):C511-20.
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Shen Y, Zheng Y, Foster DA. Phospholipase D2 stimulates cell protrusion in v-Src-transformed cells. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):201-6.
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Loo LW, Kanemitsu MY, Lau AF. In vivo association of pp60v-src and the gap-junction protein connexin 43 in v-src-transformed fibroblasts. Mol Carcinog. 1999 Jul; 25(3):187-95.
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Kanemitsu MY, Loo LW, Simon S, Lau AF, Eckhart W. Tyrosine phosphorylation of connexin 43 by v-Src is mediated by SH2 and SH3 domain interactions. J Biol Chem. 1997 Sep 05; 272(36):22824-31.