"Second Messenger Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
Descriptor ID |
D015290
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MeSH Number(s) |
G02.111.820.800 G04.835.800
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Concept/Terms |
Second Messenger Systems- Second Messenger Systems
- Second Messenger System
- System, Second Messenger
- Systems, Second Messenger
- Intracellular Second Messengers
- Intracellular Second Messenger
- Messengers, Intracellular Second
- Second Messenger, Intracellular
- Second Messengers, Intracellular
Second Messengers- Second Messengers
- Messenger, Second
- Messengers, Second
- Second Messenger
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Below are MeSH descriptors whose meaning is more general than "Second Messenger Systems".
Below are MeSH descriptors whose meaning is more specific than "Second Messenger Systems".
This graph shows the total number of publications written about "Second Messenger Systems" by people in this website by year, and whether "Second Messenger Systems" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Second Messenger Systems" by people in Profiles.
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Storer Samaniego C, Suh JH, Chattopadhyay A, Olivares K, Guy N, Sivils JC, Dey P, Yumoto F, Fletterick RJ, Strom AM, Gustafsson J?, Webb P, Cox MB. The FKBP52 Cochaperone Acts in Synergy with ?-Catenin to Potentiate Androgen Receptor Signaling. PLoS One. 2015; 10(7):e0134015.
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Ayala JC, Wang H, Silva AJ, Benitez JA. Repression by H-NS of genes required for the biosynthesis of the Vibrio cholerae biofilm matrix is modulated by the second messenger cyclic diguanylic acid. Mol Microbiol. 2015 Aug; 97(4):630-45.
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Foster DA, Salloum D, Menon D, Frias MA. Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR). J Biol Chem. 2014 Aug 15; 289(33):22583-22588.
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Moreno-Smith M, Lee SJ, Lu C, Nagaraja AS, He G, Rupaimoole R, Han HD, Jennings NB, Roh JW, Nishimura M, Kang Y, Allen JK, Armaiz GN, Matsuo K, Shahzad MM, Bottsford-Miller J, Langley RR, Cole SW, Lutgendorf SK, Siddik ZH, Sood AK. Biologic effects of dopamine on tumor vasculature in ovarian carcinoma. Neoplasia. 2013 May; 15(5):502-10.
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Horton JS, Yamamoto SY, Bryant-Greenwood GD. Relaxin modulates proinflammatory cytokine secretion from human decidual macrophages. Biol Reprod. 2011 Oct; 85(4):788-97.
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Ping Z, Liu W, Kang Z, Cai J, Wang Q, Cheng N, Wang S, Wang S, Zhang JH, Sun X. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme. Brain Res. 2010 Jul 09; 1343:178-85.
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Santiago JM, Rosas O, Torrado AI, Gonz?lez MM, Kalyan-Masih PO, Miranda JD. Molecular, anatomical, physiological, and behavioral studies of rats treated with buprenorphine after spinal cord injury. J Neurotrauma. 2009 Oct; 26(10):1783-93.
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Amidi F, Beall M, Ross MG. Cyclic adenosine monophosphate regulation of aquaporin gene expression in human amnion epithelia. Reprod Sci. 2007 Apr; 14(3):234-40.
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Santamaria F, Wils S, De Schutter E, Augustine GJ. Anomalous diffusion in Purkinje cell dendrites caused by spines. Neuron. 2006 Nov 22; 52(4):635-48.
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Ganafa AA, Walton M, Eatman D, Abukhalaf IK, Bayorh MA. Amlodipine attenuates oxidative stress-induced hypertension. Am J Hypertens. 2004 Sep; 17(9):743-8.