Tacrolimus Binding Proteins

"Tacrolimus Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of immunophilin proteins that bind to the immunosuppressive drugs TACROLIMUS (also known as FK506) and SIROLIMUS. EC 5.2.1.-

Descriptor ID	D022021
MeSH Number(s)	D08.811.399.325.500.400.700 D12.776.543.750.705.400.700 D12.776.827.275.700
Concept/Terms	Tacrolimus Binding Proteins Tacrolimus Binding Proteins FK506 Binding Protein FK506-Binding Protein Protein, FK506-Binding FKBP Rotamase Rotamase, FKBP FK506 Binding Proteins FK-506-Binding Protein FK 506 Binding Protein Protein, FK-506-Binding FKBP Rapamycin Binding Proteins Rapamycin Binding Proteins Binding Proteins, Rapamycin Rapamycin-Binding Proteins Proteins, Rapamycin-Binding

Below are MeSH descriptors whose meaning is more general than "Tacrolimus Binding Proteins".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Isomerases [D08.811.399]
cis-trans-Isomerases [D08.811.399.325]
Peptidylprolyl Isomerase [D08.811.399.325.500]
Immunophilins [D08.811.399.325.500.400]
Tacrolimus Binding Proteins [D08.811.399.325.500.400.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Immunophilins [D12.776.543.750.705.400]
Tacrolimus Binding Proteins [D12.776.543.750.705.400.700]
Receptors, Drug [D12.776.827]
Immunophilins [D12.776.827.275]
Tacrolimus Binding Proteins [D12.776.827.275.700]

Below are MeSH descriptors whose meaning is related to "Tacrolimus Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Tacrolimus Binding Proteins".

Tacrolimus Binding Proteins
Tacrolimus Binding Protein 1A

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tacrolimus Binding Proteins" by people in this website by year, and whether "Tacrolimus Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 33 publications over 14 distinct years, with a maximum of 7 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	2	0	2
2007	2	0	2
2009	0	1	1
2010	2	1	3
2011	7	0	7
2012	1	0	1
2013	1	0	1
2014	3	2	5
2015	3	1	4
2016	1	1	2
2017	2	0	2
2019	1	0	1
2020	0	1	1
2023	1	0	1

Below are the most recent publications written about "Tacrolimus Binding Proteins" by people in Profiles.

Ortiz NR, Guy N, Garcia YA, Sivils JC, Galigniana MD, Cox MB. Functions of the Hsp90-Binding FKBP Immunophilins. Subcell Biochem. 2023; 101:41-80.

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Chaurasiya S, Widmann S, Botero C, Lin CY, Gustafsson J?, Strom AM. Estrogen receptor ? exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity. PLoS One. 2020; 15(5):e0226057.

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Harris DC, Garcia YA, Samaniego CS, Rowlett VW, Ortiz NR, Payan AN, Maehigashi T, Cox MB. Functional Comparison of Human and Zebra Fish FKBP52 Confirms the Importance of the Proline-Rich Loop for Regulation of Steroid Hormone Receptor Activity. Int J Mol Sci. 2019 Oct 28; 20(21).

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Criado-Marrero M, Morales Silva RJ, Velazquez B, Hern?ndez A, Colon M, Cruz E, Soler-Cede?o O, Porter JT. Dynamic expression of FKBP5 in the medial prefrontal cortex regulates resiliency to conditioned fear. Learn Mem. 2017 04; 24(4):145-152.

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Joshi JB, Patel D, Morton DJ, Sharma P, Zou J, Hewa Bostanthirige D, Gorantla Y, Nagappan P, Komaragiri SK, Sivils JC, Xie H, Palaniappan R, Wang G, Cox MB, Chaudhary J. Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52. Mol Oncol. 2017 04; 11(4):337-357.

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Komaragiri SK, Bostanthirige DH, Morton DJ, Patel D, Joshi J, Upadhyay S, Chaudhary J. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells. Biochem Biophys Res Commun. 2016 09 09; 478(1):60-66.

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Maiar? M, Tochiki KK, Cox MB, Annan LV, Bell CG, Feng X, Hausch F, G?ranton SM. The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling. Sci Transl Med. 2016 Feb 10; 8(325):325ra19.

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Storer Samaniego C, Suh JH, Chattopadhyay A, Olivares K, Guy N, Sivils JC, Dey P, Yumoto F, Fletterick RJ, Strom AM, Gustafsson J?, Webb P, Cox MB. The FKBP52 Cochaperone Acts in Synergy with ?-Catenin to Potentiate Androgen Receptor Signaling. PLoS One. 2015; 10(7):e0134015.

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Shrestha S, Sun Y, Lufkin T, Kraus P, Or Y, Garcia YA, Guy N, Ramos P, Cox MB, Tay F, Lin VC. Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity. Int J Biol Sci. 2015; 11(4):434-47.

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Guy NC, Garcia YA, Sivils JC, Galigniana MD, Cox MB. Functions of the Hsp90-binding FKBP immunophilins. Subcell Biochem. 2015; 78:35-68.

View in: PubMed

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