Vaccines, Inactivated

"Vaccines, Inactivated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.

Descriptor ID	D015164
MeSH Number(s)	D20.215.894.830
Concept/Terms	Vaccines, Inactivated Vaccines, Inactivated Inactivated Vaccines Killed Vaccines Vaccines, Killed

Below are MeSH descriptors whose meaning is more general than "Vaccines, Inactivated".

Chemicals and Drugs [D]
Complex Mixtures [D20]
Biological Products [D20.215]
Vaccines [D20.215.894]
Vaccines, Inactivated [D20.215.894.830]

Below are MeSH descriptors whose meaning is related to "Vaccines, Inactivated".

Below are MeSH descriptors whose meaning is more specific than "Vaccines, Inactivated".

Vaccines, Inactivated
Poliovirus Vaccine, Inactivated

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Vaccines, Inactivated" by people in this website by year, and whether "Vaccines, Inactivated" was a major or minor topic of these publications.

Bar chart showing 13 publications over 8 distinct years, with a maximum of 4 publications in 2010

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2002	1	1
2010	4	4
2011	1	1
2013	1	1
2015	1	1
2016	1	1
2017	3	3
2018	1	1

Below are the most recent publications written about "Vaccines, Inactivated" by people in Profiles.

Tuchynskaya K, Vorovitch M, Kruglov Y, Mostipanova G, Kholodilov I, Ivanova A, Kuchina V, Rogova A, Karganova G. Mono-WNV and combined WNV/TBEV inactivated vaccine efficacy against a wide range of WNV and TBEV strains. Front Immunol. 2025; 16:1715371.

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Tsai WY, Pierson TC, Wrammert J, Dejnirattisai W, Jumnainsong A, Mongkolsapaya J, Screaton G, Crowe JE, Wang WK. Mature dengue virus particles inactivated by a non-ionic detergent retain quaternary neutralizing epitopes and induce potent neutralizing antibodies. Front Immunol. 2025; 16:1626823.

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Diaz C, Lin L, Martinez LJ, Eckels KH, Campos M, Jarman RG, De La Barrera R, Lepine E, Toussaint JF, Febo I, Innis BL, Thomas SJ, Schmidt AC. Phase I Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults from Puerto Rico. Am J Trop Med Hyg. 2018 05; 98(5):1435-1443.

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Caballero Van Dyke MC, Wormley FL. A Call to Arms: Quest for a Cryptococcal Vaccine. Trends Microbiol. 2018 05; 26(5):436-446.

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Menegay JL, Xu X, Sunil TS, Okulicz JF. Live versus attenuated influenza vaccine uptake and post-vaccination influenza-like illness outcomes in HIV-infected US Air Force members. J Clin Virol. 2017 10; 95:72-75.

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Hurtgen BJ, Hung CY. Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection. Methods Mol Biol. 2017; 1625:45-64.

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Cimica V, Boigard H, Bhatia B, Fallon JT, Alimova A, Gottlieb P, Galarza JM. Novel Respiratory Syncytial Virus-Like Particle Vaccine Composed of the Postfusion and Prefusion Conformations of the F Glycoprotein. Clin Vaccine Immunol. 2016 06; 23(6):451-9.

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Zhai B, Wozniak KL, Masso-Silva J, Upadhyay S, Hole C, Rivera A, Wormley FL, Lin X. Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants. mBio. 2015 Oct 06; 6(5):e01433-15.

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Chu CS, Boyer JD, Jawad A, McDonald K, Rogers WT, Luning Prak ET, Sullivan KE. Immunologic consequences of chemotherapy for ovarian cancer: impaired responses to the influenza vaccine. Vaccine. 2013 Nov 04; 31(46):5435-42.

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Hoft DF, Babusis E, Worku S, Spencer CT, Lottenbach K, Truscott SM, Abate G, Sakala IG, Edwards KM, Creech CB, Gerber MA, Bernstein DI, Newman F, Graham I, Anderson EL, Belshe RB. Live and inactivated influenza vaccines induce similar humoral responses, but only live vaccines induce diverse T-cell responses in young children. J Infect Dis. 2011 Sep 15; 204(6):845-53.

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