"Uncoupling Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.
| Descriptor ID |
D014475
|
| MeSH Number(s) |
D27.505.519.389.936
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Uncoupling Agents".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Agents".
This graph shows the total number of publications written about "Uncoupling Agents" by people in this website by year, and whether "Uncoupling Agents" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Uncoupling Agents" by people in Profiles.
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Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56.
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C?novas D, Mukhopadhyay R, Rosen BP, de Lorenzo V. Arsenate transport and reduction in the hyper-tolerant fungus Aspergillus sp. P37. Environ Microbiol. 2003 Nov; 5(11):1087-93.
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DasGupta SF, Rapoport SI, Gerschenson M, Murphy E, Fiskum G, Russell SJ, Chandrasekaran K. ATP synthesis is coupled to rat liver mitochondrial RNA synthesis. Mol Cell Biochem. 2001 May; 221(1-2):3-10.