"Pyruvate Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.
| Descriptor ID |
D011770
|
| MeSH Number(s) |
D08.811.913.696.620.695
|
| Concept/Terms |
Pyruvate Kinase L- Pyruvate Kinase L
- L-Type Pyruvate Kinase
- L Type Pyruvate Kinase
- Pyruvate Kinase, L-Type
|
Below are MeSH descriptors whose meaning is more general than "Pyruvate Kinase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Kinase".
This graph shows the total number of publications written about "Pyruvate Kinase" by people in this website by year, and whether "Pyruvate Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2018 | 1 | 2 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Pyruvate Kinase" by people in Profiles.
-
Lee KCY, Williams AL, Wang L, Xie G, Jia W, Fujimoto A, Gerschenson M, Shohet RV. PKM2 regulates metabolic flux and oxidative stress in the murine heart. Physiol Rep. 2024 Sep; 12(17):e70040.
-
Fu J, Xiong Z, Huang C, Li J, Yang W, Han Y, Paiboonrungruan C, Major MB, Chen KN, Kang X, Chen X. Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus. J Biol Chem. 2019 01 04; 294(1):327-340.
-
Williams AL, Khadka V, Tang M, Avelar A, Schunke KJ, Menor M, Shohet RV. HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction. Physiol Genomics. 2018 07 01; 50(7):479-494.
-
Peng F, Widmann S, W?nsche A, Duan K, Donovan KA, Dobson RCJ, Lenski RE, Cooper TF. Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria. Mol Biol Evol. 2018 01 01; 35(1):202-210.
-
Rivera-Rivera L, Perez-Laspiur J, Col?n K, Mel?ndez LM. Inhibition of interferon response by cystatin B: implication in HIV replication of macrophage reservoirs. J Neurovirol. 2012 Feb; 18(1):20-9.
-
Zhang X, Yang F, Shim JY, Kirk KL, Anderson DE, Chen X. Identification of arsenic-binding proteins in human breast cancer cells. Cancer Lett. 2007 Sep 18; 255(1):95-106.
-
Das S, Saha AK, Remaley AT, Glew RH, Dowling JN, Kajiyoshi M, Gottlieb M. Hydrolysis of phosphoproteins and inositol phosphates by cell surface phosphatase of Leishmania donovani. Mol Biochem Parasitol. 1986 Aug; 20(2):143-53.