Phosphoprotein Phosphatases

"Phosphoprotein Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)

Descriptor ID	D010749
MeSH Number(s)	D08.811.277.352.650.625
Concept/Terms	Phosphoprotein Phosphatases Phosphoprotein Phosphatases Phosphatases, Phosphoprotein Serine-Threonine Phosphatase Phosphatase, Serine-Threonine Serine Threonine Phosphatase Protein Phosphatases Phosphatases, Protein Protein-Serine-Threonine Phosphatase Phosphatase, Protein-Serine-Threonine Protein Serine Threonine Phosphatase Phosphoprotein Phosphatase Phosphatase, Phosphoprotein Phosphoprotein Phosphohydrolase Phosphohydrolase, Phosphoprotein Ecto-Phosphoprotein Phosphatase Ecto-Phosphoprotein Phosphatase Ecto Phosphoprotein Phosphatase Phosphatase, Ecto-Phosphoprotein Nuclear Protein Phosphatase Nuclear Protein Phosphatase Phosphatase, Nuclear Protein Protein Phosphatase, Nuclear Phosphohistone Phosphatase Phosphohistone Phosphatase Phosphatase, Phosphohistone Protein-Threonine Phosphatase Protein-Threonine Phosphatase Phosphatase, Protein-Threonine Protein Threonine Phosphatase Threonine Phosphatase Phosphatase, Threonine Phosphoseryl-Protein Phosphatase Phosphoseryl-Protein Phosphatase Phosphatase, Phosphoseryl-Protein Phosphoseryl Protein Phosphatase Protein Phosphatase C Protein Phosphatase C Phosphatase C, Protein Protein Phosphatase C-I Protein Phosphatase C-I Phosphatase C-I, Protein Protein Phosphatase C I Protein Phosphatase C-II Protein Phosphatase C-II Phosphatase C-II, Protein Protein Phosphatase C II Protein Phosphatase H-II Protein Phosphatase H-II Phosphatase H-II, Protein Protein Phosphatase H II Casein Phosphatase Casein Phosphatase Phosphatase, Casein Phosphoprotein Phosphatase-2C Phosphoprotein Phosphatase-2C Phosphatase-2C, Phosphoprotein Phosphoprotein Phosphatase 2C

Below are MeSH descriptors whose meaning is more general than "Phosphoprotein Phosphatases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Monoester Hydrolases [D08.811.277.352.650]
Phosphoprotein Phosphatases [D08.811.277.352.650.625]

Below are MeSH descriptors whose meaning is related to "Phosphoprotein Phosphatases".

Below are MeSH descriptors whose meaning is more specific than "Phosphoprotein Phosphatases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Phosphoprotein Phosphatases" by people in this website by year, and whether "Phosphoprotein Phosphatases" was a major or minor topic of these publications.

Bar chart showing 34 publications over 18 distinct years, with a maximum of 5 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2000	0	1	1
2001	1	0	1
2002	4	0	4
2003	2	1	3
2004	0	1	1
2005	3	2	5
2006	2	0	2
2007	1	0	1
2008	2	0	2
2009	0	2	2
2010	2	1	3
2013	2	0	2
2019	2	0	2
2021	0	1	1
2022	1	0	1
2023	1	0	1
2026	1	0	1

Below are the most recent publications written about "Phosphoprotein Phosphatases" by people in Profiles.

Liu K, He J, Wu Y, Zhao C, Yan S, Xiong F, Liu X, Yao X, Fu C. The AAA-ATPase Yta4 inhibits the interaction between Ppa2 and Atg43 to promote Atg43 phosphorylation and mitophagy. J Biol Chem. 2026 Apr; 302(4):111326.

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Nguyen H, Kettenbach AN. Substrate and phosphorylation site selection by phosphoprotein phosphatases. Trends Biochem Sci. 2023 08; 48(8):713-725.

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Alphonse S, Djemil I, Piserchio A, Ghose R. Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb. Proc Natl Acad Sci U S A. 2022 06 28; 119(26):e2201800119.

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Xu L, Ali M, Duan W, Yuan X, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z, Liu D, Liu X, Yao X. Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation. Cell Rep. 2021 07 13; 36(2):109343.

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Sullivan DR, Morrison FG, Wolf EJ, Logue MW, Fortier CB, Salat DH, Fonda JR, Stone A, Schichman S, Milberg W, McGlinchey R, Miller MW. The PPM1F gene moderates the association between PTSD and cortical thickness. J Affect Disord. 2019 12 01; 259:201-209.

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Tripathi A, Singha UK, Paromov V, Hill S, Pratap S, Rose K, Chaudhuri M. The Cross Talk between TbTim50 and PIP39, Two Aspartate-Based Protein Phosphatases, Maintains Cellular Homeostasis in Trypanosoma brucei. mSphere. 2019 08 07; 4(4).

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Akbari MR, Lepage P, Rosen B, McLaughlin J, Risch H, Minden M, Narod SA. PPM1D mutations in circulating white blood cells and the risk for ovarian cancer. J Natl Cancer Inst. 2014 Jan; 106(1):djt323.

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Temel DB, Dutta K, Alphonse S, Nourikyan J, Grangeasse C, Ghose R. Regulatory interactions between a bacterial tyrosine kinase and its cognate phosphatase. J Biol Chem. 2013 May 24; 288(21):15212-28.

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Hou H, Wang F, Zhang W, Wang D, Li X, Bartlam M, Yao X, Rao Z. Structure-functional analyses of CRHSP-24 plasticity and dynamics in oxidative stress response. J Biol Chem. 2011 Mar 18; 286(11):9623-35.

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Ammosova T, Yedavalli VR, Niu X, Jerebtsova M, Van Eynde A, Beullens M, Bollen M, Jeang KT, Nekhai S. Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem. 2011 Feb 04; 286(5):3798-804.

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