Thioctic Acid

"Thioctic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Descriptor ID	D008063
MeSH Number(s)	D02.241.803 D02.886.778.827 D08.211.906 D10.251.941
Concept/Terms	Thioctic Acid Thioctic Acid alpha-Lipoic Acid Acid, alpha-Lipoic alpha Lipoic Acid Lipoic Acid Azulipont Azulipont biomo-lipon biomo-lipon biomo lipon biomolipon alpha-Liponsaure von ct alpha-Liponsaure von ct alpha Liponsaure von ct alphaLiponsaure von ct espa-lipon espa-lipon espa lipon espalipon Pleomix-Alpha N Pleomix-Alpha N Pleomix Alpha N PleomixAlpha N alpha-Liponaure Heumann alpha-Liponaure Heumann alpha Liponaure Heumann alphaLiponaure Heumann Neurium Neurium Pleomix-Alpha Pleomix-Alpha Pleomix Alpha PleomixAlpha Juthiac Juthiac Alphaflam Alphaflam duralipon duralipon MTW-Alphaliponsaure MTW-Alphaliponsaure MTW Alphaliponsaure MTWAlphaliponsaure Fenint Fenint Liponsaure-ratiopharm Liponsaure-ratiopharm Liponsaure ratiopharm Liponsaureratiopharm alpha-Vibolex alpha-Vibolex alpha Vibolex alphaVibolex Alpha-Liponsaure Sofotec Alpha-Liponsaure Sofotec Alpha Liponsaure Sofotec AlphaLiponsaure Sofotec Alpha-Lipon Stada Alpha-Lipon Stada Alpha Lipon Stada AlphaLipon Stada Tromlipon Tromlipon Verla-Lipon Verla-Lipon Verla Lipon VerlaLipon Thioctacide T Thioctacide T Thioctacid Thioctacid Alpha-Lipogamma Alpha-Lipogamma Alpha Lipogamma AlphaLipogamma Thiogamma oral Thiogamma Injekt Thiogamma Injekt Injekt, Thiogamma Alpha-Lippon AL Alpha-Lippon AL Alpha Lippon AL AlphaLippon AL

Below are MeSH descriptors whose meaning is more general than "Thioctic Acid".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Thioctic Acid [D02.241.803]
Sulfur Compounds [D02.886]
Thiophenes [D02.886.778]
Thioctic Acid [D02.886.778.827]
Enzymes and Coenzymes [D08]
Coenzymes [D08.211]
Thioctic Acid [D08.211.906]
Lipids [D10]
Fatty Acids [D10.251]
Thioctic Acid [D10.251.941]

Below are MeSH descriptors whose meaning is related to "Thioctic Acid".

Below are MeSH descriptors whose meaning is more specific than "Thioctic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thioctic Acid" by people in this website by year, and whether "Thioctic Acid" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2007 and 2016 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	1	1	2
2008	1	0	1
2009	1	0	1
2015	0	1	1
2016	2	0	2
2017	0	1	1
2018	2	0	2
2021	1	0	1
2025	1	0	1

Below are the most recent publications written about "Thioctic Acid" by people in Profiles.

Pal S, Salzman EE, Ramirez D, Chen H, Perez CA, Dale K, Ghosh SK, Lin L, Messersmith PB. Versatile Solid-State Medical Superglue Precursors of a-Lipoic Acid. J Am Chem Soc. 2025 Apr 23; 147(16):13377-13384.

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Wasti S, Sah N, Lee CN, Jha R, Mishra B. Dietary supplementation of alpha-lipoic acid mitigates the negative effects of heat stress in broilers. PLoS One. 2021; 16(7):e0254936.

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Black DM, Robles G, Lopez P, Bach SBH, Alvarez M, Whetten RL. Liquid Chromatography Separation and Mass Spectrometry Detection of Silver-Lipoate Ag29(LA)12 Nanoclusters: Evidence of Isomerism in the Solution Phase. Anal Chem. 2018 02 06; 90(3):2010-2017.

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Zhou K, Enkhjargal B, Xie Z, Sun C, Wu L, Malaguit J, Chen S, Tang J, Zhang J, Zhang JH. Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat. Stroke. 2018 01; 49(1):175-183.

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Mishra B, Ripperdan R, Ortiz L, Luderer U. Very low doses of heavy oxygen ion radiation induce premature ovarian failure. Reproduction. 2017 Aug; 154(2):123-133.

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Mishra B, Ortiz L, Luderer U. Charged iron particles, components of space radiation, destroy ovarian follicles. Hum Reprod. 2016 08; 31(8):1816-26.

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Salvi A, Bankhele P, Jamil J, Chitnis MK, Njie-Mbye YF, Ohia SE, Opere CA. Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits. J Ocul Pharmacol Ther. 2016 Jul-Aug; 32(6):371-5.

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Salvi A, Bankhele P, Jamil JM, Kulkarni-Chitnis M, Njie-Mbye YF, Ohia SE, Opere CA. Pharmacological Actions of Hydrogen Sulfide Donors on Sympathetic Neurotransmission in the Bovine Anterior Uvea, In Vitro. Neurochem Res. 2016 May; 41(5):1020-8.

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Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009 Feb; 43(2):156-64.

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Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med. 2009 Feb; 13(2):320-33.

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