Below are the most recent publications written about "Ligands" by people in Profiles.
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Wang M, Du G, Yongo-Luwawa C, Lu A, Kinrade B, Munro K, Klose KE, Lubell WD, Davies P, Guo S. Peptide-based ligand antagonists block a Vibrio cholerae adhesin. FEBS Lett. 2026 Mar; 600(5):631-643.
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Liu M, Wan S, Guo S, Liu J, Li W, Wang L, Li F, Zhang J, Liu X, Liu D, Yao X, Gao J, Ruan K, He W. Fragment-Based Discovery of a Small-Molecule RhoGDI2 Ligand, HR3119, that Inhibits Cancer Cell Migration. ACS Chem Biol. 2025 11 21; 20(11):2584-2592.
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Patra S, Namballa HK, Gudipally AR, Xie L, Xie L, Harding WW. Discovery of a selective a2C-AR scaffold from a molecular hybridization approach. Bioorg Med Chem. 2025 Dec 15; 131:118424.
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Maniaci B, Mealka M, Bobkov AA, Stec B, Huxford T, Love JJ. Incorporating Metal-Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers. Biochemistry. 2025 08 05; 64(15):3237-3247.
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Okpattah D, Karki A, Pillarsetty NVK, Harding WW. Synthesis and evaluation of aporphinoid 5-HT7AR ligands as inhibitors of PC3 prostate cancer cell growth. Bioorg Med Chem Lett. 2025 Dec 01; 128:130328.
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Iniguez E, Rodriguez F, Husseneder C, Foil L, Maldonado RA. Ligand-lytic peptides for specific targeting of Leishmania major and Trypanosoma cruzi parasites. Front Cell Infect Microbiol. 2025; 15:1595333.
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Kiaei N, Malik A, Idahosa SO, Lee KK, Endo-Umeda K, Makishima M, Kawamura A, Higuchi S. Python-derived 16a-Hydroxylated Bile Acid, Pythocholic Acid is a ligand for TGR5, not farnesoid X receptors and vitamin D receptors. Biochem Biophys Res Commun. 2025 03 05; 751:151453.
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Delaitre C, Boisbrun M, Acherar S, Dias A, Kleinclauss A, Achard M, Colin M, Nguyen TM, Humbert N, Chmeis K, Martinez KL, Gilles N, Robin P, Lecat S, Dupuis F. Synthesis and Pharmacological Characterization of Fluorescent Ligands Targeting the Angiotensin II Receptors Derived from Agonists, ?-Arrestin-Biased Agonists, and Antagonists. J Med Chem. 2024 Nov 28; 67(22):20275-20297.
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Dorogan M, Namballa HK, Harding WW. Natural Product-Inspired Dopamine Receptor Ligands. J Med Chem. 2024 08 08; 67(15):12463-12484.
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Wang B, Kobeissy F, Golpich M, Cai G, Li X, Abedi R, Haskins W, Tan W, Benner SA, Wang KKW. Aptamer Technologies in Neuroscience, Neuro-Diagnostics and Neuro-Medicine Development. Molecules. 2024 Mar 02; 29(5).