"Kainic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
| Descriptor ID |
D007608
|
| MeSH Number(s) |
D03.383.773.400
|
| Concept/Terms |
Kainic Acid- Kainic Acid
- Acid, Kainic
- Digenic Acid
- Acid, Digenic
|
Below are MeSH descriptors whose meaning is more general than "Kainic Acid".
Below are MeSH descriptors whose meaning is more specific than "Kainic Acid".
This graph shows the total number of publications written about "Kainic Acid" by people in this website by year, and whether "Kainic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 4 | 5 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 2 | 3 |
| 2016 | 0 | 3 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kainic Acid" by people in Profiles.
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Panlilio JM, Jones IT, Salanga MC, Aluru N, Hahn ME. Developmental Exposure to Domoic Acid Disrupts Startle Response Behavior and Circuitry in Zebrafish. Toxicol Sci. 2021 08 03; 182(2):310-326.
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Mohandass A, Surenkhuu B, Covington K, Baskaran P, Lehmann T, Thyagarajan B. Kainic Acid Activates TRPV1 via a Phospholipase C/PIP2-Dependent Mechanism in Vitro. ACS Chem Neurosci. 2020 10 07; 11(19):2999-3007.
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Grattan LM, Boushey CJ, Liang Y, Lefebvre KA, Castellon LJ, Roberts KA, Toben AC, Morris JG. Repeated Dietary Exposure to Low Levels of Domoic Acid and Problems with Everyday Memory: Research to Public Health Outreach. Toxins (Basel). 2018 02 28; 10(3).
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Xiao L, Chang SY, Xiong ZG, Selveraj P, Peng Loh Y. Absence of Carboxypeptidase E/Neurotrophic Factor-?1 in Knock-Out Mice Leads to Dysfunction of BDNF-TRKB Signaling in Hippocampus. J Mol Neurosci. 2017 May; 62(1):79-87.
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Grattan LM, Boushey C, Tracy K, Trainer VL, Roberts SM, Schluterman N, Morris JG. The association between razor clam consumption and memory in the CoASTAL cohort. Harmful Algae. 2016 07; 57(Pt B):20-25.
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Boushey CJ, Delp EJ, Ahmad Z, Wang Y, Roberts SM, Grattan LM. Dietary assessment of domoic acid exposure: What can be learned from traditional methods and new applications for a technology assisted device. Harmful Algae. 2016 07; 57(Pt B):51-55.
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Tracy K, Boushey CJ, Roberts SM, Morris JG, Grattan LM. Communities advancing the studies of Tribal nations across their lifespan: Design, methods, and baseline of the CoASTAL cohort. Harmful Algae. 2016 07; 57(Pt B):9-19.
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Anastassov I, Ripps H, Chappell RL. Cytoprotection by endogenous zinc in the vertebrate retina. J Neurochem. 2014 Apr; 129(2):249-55.
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Abushik PA, Sibarov DA, Eaton MJ, Skatchkov SN, Antonov SM. Kainate-induced calcium overload of cortical neurons in vitro: Dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain. Cell Calcium. 2013 Aug; 54(2):95-104.
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Iniouchine MY, Sibarov DA, Vol'nova AB. Comparative analysis of changes in membrane currents in neurons and astrocytes in rat hippocampal slices after stimulation of glutamatergic transmission. Dokl Biol Sci. 2013 Mar; 449:65-7.