Corticotropin-Releasing Hormone
"Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
| Descriptor ID |
D003346
|
| MeSH Number(s) |
D06.472.699.327.740.140 D12.644.400.400.740.140 D12.644.548.365.740.140 D12.776.631.650.405.740.140
|
| Concept/Terms |
Corticotropin-Releasing Hormone- Corticotropin-Releasing Hormone
- Corticotropin Releasing Hormone
- Corticoliberin
- Corticotropin-Releasing Factor
- Corticotropin Releasing Factor
- Corticotropin-Releasing Factor-41
- Corticotropin Releasing Factor 41
- CRF (ACTH)
- Corticotropin-Releasing Hormone-41
- Corticotropin Releasing Hormone 41
- CRF-41
- ACTH-Releasing Hormone
- ACTH Releasing Hormone
- ACTH-Releasing Factor
- ACTH Releasing Factor
|
Below are MeSH descriptors whose meaning is more general than "Corticotropin-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Corticotropin-Releasing Hormone" by people in this website by year, and whether "Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 1 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Corticotropin-Releasing Hormone" by people in Profiles.
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Pag?n-Busig? JE, L?pez-Carrasquillo J, Appleyard CB, Torres-Rever?n A. Beyond depression and anxiety; a systematic review about the role of corticotropin-releasing hormone antagonists in diseases of the pelvic and abdominal organs. PLoS One. 2022; 17(3):e0264909.
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Uribe KP, Correa VL, Pinales BE, Flores RJ, Cruz B, Shan Z, Bruijnzeel AW, Khan AM, O'Dell LE. Overexpression of corticotropin-releasing factor in the nucleus accumbens enhances the reinforcing effects of nicotine in intact?female versus male?and ovariectomized female rats. Neuropsychopharmacology. 2020 01; 45(2):394-403.
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Torres-Rever?n A, Rivera LL, Flores I, Appleyard CB. Environmental Manipulations as an Effective Alternative Treatment to Reduce Endometriosis Progression. Reprod Sci. 2018 09; 25(9):1336-1348.
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Balan I, Warnock KT, Puche A, Gondre-Lewis MC, Aurelian L. Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity. Brain Behav Immun. 2018 03; 69:139-153.
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Gondr?-Lewis MC, Warnock KT, Wang H, June HL, Bell KA, Rabe H, Tiruveedhula VV, Cook J, L?ddens H, Aurelian L, June HL. Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABA(A) mechanism. Stress. 2016; 19(2):235-47.
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Boyson CO, Holly EN, Shimamoto A, Albrechet-Souza L, Weiner LA, DeBold JF, Miczek KA. Social stress and CRF-dopamine interactions in the VTA: role in long-term escalation of cocaine self-administration. J Neurosci. 2014 May 07; 34(19):6659-67.
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Mellman TA. A laboratory model intervention that prevents a stress effect on sleep. Sleep. 2013 Apr 01; 36(4):455-6.
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Watts AG, Khan AM. Identifying links in the chain: the dynamic coupling of catecholamines, peptide synthesis, and peptide release in hypothalamic neuroendocrine neurons. Adv Pharmacol. 2013; 68:421-44.
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Cuevas M, Flores I, Thompson KJ, Ramos-Ortolaza DL, Torres-Reveron A, Appleyard CB. Stress exacerbates endometriosis manifestations and inflammatory parameters in an animal model. Reprod Sci. 2012 Aug; 19(8):851-62.
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Lutfy K, Aimiuwu O, Mangubat M, Shin CS, Nerio N, Gomez R, Liu Y, Friedman TC. Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors. J Neurochem. 2012 Mar; 120(6):1108-16.