Cardiotonic Agents

"Cardiotonic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

Descriptor ID	D002316
MeSH Number(s)	D27.505.954.411.222 D27.720.799.080
Concept/Terms	Cardiotonic Agents Cardiotonic Agents Cardiac Stimulants Inotropic Agents, Positive Cardiac Cardiotonic Drugs Cardiotonics Myocardial Stimulants Cardioprotective Agents

Below are MeSH descriptors whose meaning is more general than "Cardiotonic Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Cardiovascular Agents [D27.505.954.411]
Cardiotonic Agents [D27.505.954.411.222]
Specialty Uses of Chemicals [D27.720]
Protective Agents [D27.720.799]
Cardiotonic Agents [D27.720.799.080]

Below are MeSH descriptors whose meaning is more specific than "Cardiotonic Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cardiotonic Agents" by people in this website by year, and whether "Cardiotonic Agents" was a major or minor topic of these publications.

Bar chart showing 33 publications over 22 distinct years, with a maximum of 5 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	1	0	1
2002	1	0	1
2003	0	1	1
2004	1	0	1
2005	0	2	2
2007	1	0	1
2008	1	0	1
2009	1	0	1
2010	2	0	2
2011	1	0	1
2013	2	3	5
2014	1	2	3
2015	2	0	2
2016	1	0	1
2017	2	0	2
2018	1	0	1
2019	1	0	1
2020	1	0	1
2021	1	0	1
2022	0	2	2
2025	1	0	1

Below are the most recent publications written about "Cardiotonic Agents" by people in Profiles.

McNamara PJ, Chock VY, Rahde-Bischoff A, Gabrio J, Johnson KJ, Harmon HM, Montoya-Williams D, Colaizy TT, Katheria AC, Ines F, Sorrells K, Battersby C, Levy PT, Rysavy MA, Bhombal S, Laughon MM, Carper B, Hintz SR, Das A, Bell EF. Evaluating the efficacy and safety of milrinone for prevention of post-patent ductus arteriosus closure syndrome (the MIDAS trial) in extremely preterm infants: a multicentre, double-masked, randomised, placebo-controlled trial. BMJ Open. 2025 Aug 26; 15(8):e105018.

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Dagan M, Lankaputhra M, Yeung T, Tee SL, Bader I, Easton K, Linton A, McLean C, Taylor A, Bergin P, Kaye DM, Leet A, Hare JL, Patel HC. Incidence and Predictors of Eosinophilic Myocardial Hypersensitivity in Patients Receiving Home Dobutamine. J Cardiovasc Pharmacol. 2022 10 01; 80(4):623-628.

View in: PubMed
Yeung T, Dagan M, Lankaputhra M, Cieslik L, Warner V, Leet A, Hare JL, Bergin P, Taylor AJ, Kaye DM, Patel HC. Levosimendan and Continuous Outpatient Support With Inotropes in Patients With Advanced Heart Failure: A Single-Centre Descriptive Study. J Cardiovasc Pharmacol. 2022 04 01; 79(4):583-592.

View in: PubMed
Thakur V, Alcoreza N, Delgado M, Joddar B, Chattopadhyay M. Cardioprotective Effect of Glycyrrhizin on Myocardial Remodeling in Diabetic Rats. Biomolecules. 2021 04 13; 11(4).

View in: PubMed
Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats. Life Sci. 2020 Sep 01; 256:117855.

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Sato R, Ariyoshi N, Hasegawa D, Crossey E, Hamahata N, Ishihara T, Nasu M, Devendra G. Effects of Inotropes on the Mortality in Patients With Septic Shock. J Intensive Care Med. 2021 Feb; 36(2):211-219.

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Khuchua Z, Glukhov AI, Strauss AW, Javadov S. Elucidating the Beneficial Role of PPAR Agonists in Cardiac Diseases. Int J Mol Sci. 2018 Nov 04; 19(11).

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Javadov S, Jang S, Parodi-Rull?n R, Khuchua Z, Kuznetsov AV. Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection? Cell Mol Life Sci. 2017 08; 74(15):2795-2813.

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Efird JT, Kiser AC, Crane PB, Landrine H, Kindell LC, Nelson MA, Jindal C, Sarpong DF, Griffin WF, Ferguson TB, Chitwood WR, Davies SW, Kypson AP, Gudimella P, Anderson EJ. Perioperative Inotrope Therapy and Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery: Evidence of a Racial Disparity. Pharmacotherapy. 2017 03; 37(3):297-304.

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Lipshultz SE, Anderson LM, Miller TL, Gerschenson M, Stevenson KE, Neuberg DS, Franco VI, LiButti DE, Silverman LB, Vrooman LM, Sallan SE. Impaired mitochondrial function is abrogated by dexrazoxane in doxorubicin-treated childhood acute lymphoblastic leukemia survivors. Cancer. 2016 Mar 15; 122(6):946-53.

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