Anti-Inflammatory Agents, Non-Steroidal

"Anti-Inflammatory Agents, Non-Steroidal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Descriptor ID	D000894
MeSH Number(s)	D27.505.696.663.850.014.040.500 D27.505.954.158.030 D27.505.954.329.030
Concept/Terms	Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Antiinflammatory Agents, Non Steroidal NSAIDs Non-Steroidal Anti-Inflammatory Agents Non Steroidal Anti Inflammatory Agents Nonsteroidal Anti-Inflammatory Agents Nonsteroidal Anti Inflammatory Agents Anti Inflammatory Agents, Nonsteroidal Antiinflammatory Agents, Nonsteroidal Nonsteroidal Antiinflammatory Agents Analgesics, Anti-Inflammatory Analgesics, Anti-Inflammatory Anti-Inflammatory Analgesics Aspirin-Like Agents Aspirin-Like Agents Aspirin Like Agents

Below are MeSH descriptors whose meaning is more general than "Anti-Inflammatory Agents, Non-Steroidal".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Peripheral Nervous System Agents [D27.505.696.663]
Sensory System Agents [D27.505.696.663.850]
Analgesics [D27.505.696.663.850.014]
Analgesics, Non-Narcotic [D27.505.696.663.850.014.040]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.696.663.850.014.040.500]
Therapeutic Uses [D27.505.954]
Anti-Inflammatory Agents [D27.505.954.158]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.158.030]
Antirheumatic Agents [D27.505.954.329]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.329.030]

Below are MeSH descriptors whose meaning is related to "Anti-Inflammatory Agents, Non-Steroidal".

Below are MeSH descriptors whose meaning is more specific than "Anti-Inflammatory Agents, Non-Steroidal".

Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in this website by year, and whether "Anti-Inflammatory Agents, Non-Steroidal" was a major or minor topic of these publications.

Bar chart showing 126 publications over 28 distinct years, with a maximum of 12 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	1	3
1997	1	0	1
1999	0	1	1
2000	2	0	2
2002	4	3	7
2003	7	4	11
2004	3	5	8
2005	6	6	12
2006	3	1	4
2007	3	3	6
2008	4	3	7
2009	1	3	4
2010	5	0	5
2011	4	1	5
2012	3	3	6
2013	3	3	6
2014	0	1	1
2015	5	3	8
2016	5	6	11
2017	3	1	4
2018	2	1	3
2019	2	0	2
2020	2	0	2
2021	0	1	1
2022	1	1	2
2023	0	1	1
2024	0	1	1
2025	0	2	2

Below are the most recent publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in Profiles.

Hurwitz LM, O'Brien KM, Townsend MK, Reid BM, Fridley BL, Fan W, Schabath MB, Bodelon C, Chan AT, Fortner RT, H?kansson N, Harris HR, Lacey JV, Liao LM, Merritt MA, Patel AV, Poynter JN, Robien K, Sandler DP, Wentzensen N, Wolk A, Zheng W, Tworoger SS, Trabert B. Longer-term aspirin use and subsequent ovarian cancer risk in the Ovarian Cancer Cohort Consortium. Int J Epidemiol. 2026 Feb 18; 55(2).

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Patel N, Desai A, Vyas B, Shah P, Shubhada M, Milind U, Pathak K, Chougule MB. Integration of Synchronizing?In Silico,?In Vitro, and?In Vivo?Strategies for the Development of Antipsoriatic Apremilast-loaded Nanostructured Lipid Carrier Embedded in Hydrogel. AAPS PharmSciTech. 2025 Apr 25; 26(5):115.

View in: PubMed
Rault L, Raidoo S. Therapeutic Options for Unscheduled Bleeding on Hormonal Contraception. Obstet Gynecol Clin North Am. 2025 Jun; 52(2):331-346.

View in: PubMed
Asare E, Emmanuel S, Du T, Xie H, Liang D, Gao S. Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac. Molecules. 2024 Dec 12; 29(24).

View in: PubMed
Longo S, Altobelli E, Castellini C, Vernia F, Valvano M, Magistroni M, Mancusi A, Viscido A, Ashktorab H, Latella G. Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies. Int J Colorectal Dis. 2022 Mar; 37(3):521-529.

View in: PubMed
Kolawole OR, Kashfi K. NSAIDs and Cancer Resolution: New Paradigms beyond Cyclooxygenase. Int J Mol Sci. 2022 Jan 27; 23(3).

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Xu X, Ritz B, Coleman AL, Liew Z, Deapen D, Lee E, Bernstein L, Pinder R, Marshall SF, Heck JE. Non-steroidal Anti-inflammatory Drug Use and Risk of Age-Related Macular Degeneration in the California Teachers Study. Drugs Aging. 2021 09; 38(9):817-828.

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Stefanelli G, Viscido A, Valvano M, Vernia F, Frieri G, Ashktorab H, Latella G. Is mesalazine treatment effective in the prevention of diverticulitis? A review. Eur Rev Med Pharmacol Sci. 2020 08; 24(15):8164-8176.

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Chuang TD, Rehan A, Khorram O. Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells. Fertil Steril. 2020 06; 113(6):1308-1318.

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Gambardella A, Licata G, De Rosa A, Agozzino M, Giorgio CM, Alfano R, Argenziano G. Burning mouth syndrome associated with tumor necrosis factor (TNF)-a inhibitor. Int J Dermatol. 2020 Mar; 59(3):e70-e71.

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