PROFILES - Connect with RTRN Researchers

Tammi Taylor
Title Assistant Professor of Molecular Genetics
Faculty Rank Tenure Track
Degree PhD
Institution Jackson State University
Department Biology
Clusters Cancer
Cardiovascular and Related Diseases
Genes and Environmental Health/Toxicology
Infectious and Immunological Diseases
Neurological Disorders and Mental Health
Obesity and Metabolic Syndromes
Address
1400 JR Lynch Street
PO Box 18540
City Jackson
State MS
Postal Code 39217
Telephone 6019790394
Fax 601-203-5139
Email
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Awards and Honors icon

1999 Tougaloo College UNCF Tenneco Scholarship
2000 Tougaloo College UNCF- Bessise Irene Scholarship
2001 University of North TexasHealth Science Center Ronald E. McNair Post Baccularate Scholar
2003 Jackson State University Bridges to Doctorate Pre-doctoral Fellow
2004 Jackson State University FASEB Minority Trainee Travel Award
2005 Indiana University FASEB Minority Trainee Travel Award
2007 Indiana University Edwin T Harper Graduate Student Scholar
2008 Indiana University Edwin T Harper Scholar Award
2010 Emory University Fellowship in Research and Science Teaching Postdoctoral Fellow
2012 Emory University Alexorod Travel Award
2017 Jackson State university ABRCMS Judge Travel Award
2017 Jackson State University RCMI Pilot Grant

Narrative icon

  It is my goal to collaborate with individuals in the Biology department at Jackson State University and to establish my research laboratory to investigate the roles of multiple signaling pathways on enhancing endogenous repair using the barrel cortex stroke rodent model. More specifically our goal is to use a mouse model indifferent genetically modified mice models. I have the experience, dedication, and enthusiasm to make significant contributions to this project due to my background and training in the field of neurology and only have spent almost 3 years working with the stroke mice model while at Emory University as a FIRST postdoctoral fellow. During my graduate research studies, I sought to discover the role of Toll Like Receptors on Mouse embryonic stem cells and understand their function. More specifically my study focused on role of Toll Like Receptor 2 on proliferation, survival, NF-Kß translocation, and cytokine mRNA expression in LIF-maintained mouse embryonic stem cells. I discovered that Toll Like Receptor 2 mediates the latter and this data was published in 2010 in Stem Cells and Development.Not only have I obtained valuable research experience in graduate school I also gained research experience in undergraduate. I gained hematology/immunology experience in Dr. Fast laboratory at Brown University studying the effects on UV radiation on human blood that is transplanted into a hemophilia mouse model while at Tougaloo College. After graduating Tougaloo I attended JSU for my Masters and I gained Microbiology experience in Dr. Kaplan studying the STAT4 signaling pathway and Dr. Dent’s laboratory studying the effects of BLIMP1 on B cell activity during the summers at Indiana University.
In each case I have made significant contributions to the studies to the studies conducted on efforts to better understand human conditions and disease using signaling mechanisms models involved in development of stem cells. With nearly fourteen years of research experience I have gained a plethora of knowledge about many different scientific disciplines as well as many different techniques and ways to solve problems. I am a highly motivated, inquisitive, fast learning individual who works well independently as well as collaboratively. I am very excited to continue to work in the field of neurology and anesthesiology and look forward to expanding my knowledge and skill set in completing the goals of the proposed projects.

Mentorship icon

 
Availability Date:
Wednesday, July 20, 2016

I'm a new Principal Investigator at Jackson State University. As a mentee, I would like help discovering the correct path to success at a historically black institution. There are a lot more hurdles to overcome compared to working at an R1 institution and I would like a mentor who can share pointers and offer advice on how to get funding for laboratory, balance my teaching load and also get published.

I am available to mentor as:
I can help train students pursuing a career in the sciences and medical field. I have mentored graduate students working on Masters and PhD's and would love to help mold the next future scientists and engineers in my laboratory at JSU

Contact Information for Mentoring:
tammi.m.taylor@jsums.edu

Preferred Methods of Mentoring:
Email

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Mentoring Mentor

Publications icon

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1. Wei ZZ, Zhang JY, Taylor TM, Gu X, Zhao Y, Wei L. Neuroprotective and regenerative roles of intranasal Wnt-3a administration after focal ischemic stroke in mice. J Cereb Blood Flow Metab. 2018 Mar; 38(3):404-421.
2. Wei ZZ, Yu SP, Lee JH, Chen D, Taylor TM, Deveau TC, Yu AC, Wei L. Regulatory role of the JNK-STAT1/3 signaling in neuronal differentiation of cultured mouse embryonic stem cells. Cell Mol Neurobiol. 2014 Aug; 34(6):881-93.
3. Wei N, Yu SP, Gu X, Taylor TM, Song D, Liu XF, Wei L. Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice. Cell Transplant. 2013; 22(6):977-91.
4. Zeng X, Yu SP, Taylor T, Ogle M, Wei L. Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosis. Stem Cell Res. 2012 May; 8(3):357-67.
5. Hu X, Wei L, Taylor TM, Wei J, Zhou X, Wang JA, Yu SP. Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation. Am J Physiol Cell Physiol. 2011 Aug; 301(2):C362-72.
6. Ou X, Chae HD, Wang RH, Shelley WC, Cooper S, Taylor T, Kim YJ, Deng CX, Yoder MC, Broxmeyer HE. SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse. Blood. 2011 Jan 13; 117(2):440-50.
7. Taylor T, Kim YJ, Ou X, Derbigny W, Broxmeyer HE. Toll-like receptor 2 mediates proliferation, survival, NF-kappaB translocation, and cytokine mRNA expression in LIF-maintained mouse embryonic stem cells. Stem Cells Dev. 2010 Sep; 19(9):1333-41.

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Embryonic Stem Cells
Leukemia Inhibitory Factor
Toll-Like Receptor 2
NF-kappa B
Cytokines
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