"Histone Demethylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyse the removal of methyl groups from LYSINE or ARGININE residues found on HISTONES. Many histone demethylases generally function through an oxidoreductive mechanism.
| Descriptor ID |
D056466
|
| MeSH Number(s) |
D08.811.682.662.582.475
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Histone Demethylases".
Below are MeSH descriptors whose meaning is more specific than "Histone Demethylases".
This graph shows the total number of publications written about "Histone Demethylases" by people in this website by year, and whether "Histone Demethylases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
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Below are the most recent publications written about "Histone Demethylases" by people in Profiles.
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Sengupta A, Upadhyay G, Sen S, Saleque S. Reciprocal regulation of alternative lineages by Rgs18 and its transcriptional repressor Gfi1b. J Cell Sci. 2016 Jan 01; 129(1):145-54.
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McCarrey JR. EPIGENETICS. The epigenome--a family affair. Science. 2015 Nov 06; 350(6261):634-5.
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Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH. Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development. Hum Mol Genet. 2015 Aug 01; 24(15):4443-53.
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Upadhyay G, Chowdhury AH, Vaidyanathan B, Kim D, Saleque S. Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8071-6.
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Tsurumi A, Dutta P, Dutta P, Shang R, Yan SJ, Sheng R, Li WX. Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling. Sci Rep. 2013 Oct 08; 3:2894.
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Fu H, Maunakea AK, Martin MM, Huang L, Zhang Y, Ryan M, Kim R, Lin CM, Zhao K, Aladjem MI. Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle. PLoS Genet. 2013 Jun; 9(6):e1003542.
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Chowdhury AH, Ramroop JR, Upadhyay G, Sengupta A, Andrzejczyk A, Saleque S. Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST. PLoS One. 2013; 8(1):e53666.
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Saleque S, Kim J, Rooke HM, Orkin SH. Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell. 2007 Aug 17; 27(4):562-72.